Department of Pathology,
Tisch Cancer Institute,
Department of Pathology, Tisch Cancer Institute
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Tumor response to radiotherapy regulated by endothelial cell apoptosis.
Science (New York, N.Y.) May, 2003 | Pubmed ID: 12750523
Lack of p53 nuclear immunostaining is not indicative of absence of TP53 gene mutations in colorectal adenocarcinomas.
Applied immunohistochemistry & molecular morphology : AIMM / official publication of the Society for Applied Immunohistochemistry Jun, 2003 | Pubmed ID: 12777996
Array-based comparative genomic hybridization for genome-wide screening of DNA copy number in bladder tumors.
Cancer research Jun, 2003 | Pubmed ID: 12782593
Oncogenes in melanoma.
Oncogene May, 2003 | Pubmed ID: 12789285
A multigenic program mediating breast cancer metastasis to bone.
Cancer cell Jun, 2003 | Pubmed ID: 12842083
Altered expression of p27 and Skp2 proteins in prostate cancer of African-American patients.
Clinical cancer research : an official journal of the American Association for Cancer Research Jul, 2003 | Pubmed ID: 12855638
Gene discovery in bladder cancer progression using cDNA microarrays.
The American journal of pathology Aug, 2003 | Pubmed ID: 12875971
Classification and subtype prediction of adult soft tissue sarcoma by functional genomics.
The American journal of pathology Aug, 2003 | Pubmed ID: 12875988
Tumor suppressor role for myopodin in bladder cancer: loss of nuclear expression of myopodin is cell-cycle dependent and predicts clinical outcome.
Oncogene Aug, 2003 | Pubmed ID: 12917631
Adrenocortical adenoma and carcinoma: histopathological and molecular comparative analysis.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc Aug, 2003 | Pubmed ID: 12920217
Pharmacologic inactivation of kinase suppressor of ras-1 abrogates Ras-mediated pancreatic cancer.
Nature medicine Oct, 2003 | Pubmed ID: 12960962
Tumor promotion by Mdm2 splice variants unable to bind p53.
Cancer research Sep, 2003 | Pubmed ID: 14522887
p73alpha regulation by Chk1 in response to DNA damage.
Molecular and cellular biology Nov, 2003 | Pubmed ID: 14585975
Mutations of the PML tumor suppressor gene in acute promyelocytic leukemia.
Blood Mar, 2004 | Pubmed ID: 14630830
Genetic signatures of differentiation induced by 1alpha,25-dihydroxyvitamin D3 in human colon cancer cells.
Cancer research Nov, 2003 | Pubmed ID: 14633706
Comparison of gene expression profiles in laser-microdissected, nonembedded, and OCT-embedded tumor samples by oligonucleotide microarray analysis.
Clinical chemistry Dec, 2003 | Pubmed ID: 14633888
p73 Expression in human normal and tumor tissues: loss of p73alpha expression is associated with tumor progression in bladder cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research Nov, 2003 | Pubmed ID: 14654547
Pten dose dictates cancer progression in the prostate.
PLoS biology Dec, 2003 | Pubmed ID: 14691534
MDM2 and prognosis.
Molecular cancer research : MCR Jan, 2004 | Pubmed ID: 14757840
Loss of the tumor suppressor PML in human cancers of multiple histologic origins.
Journal of the National Cancer Institute Feb, 2004 | Pubmed ID: 14970276
Histone deacetylase inhibitors: assays to assess effectiveness in vitro and in vivo.
Methods in enzymology , 2004 | Pubmed ID: 14975307
p53 and RB: simple interesting correlates or tumor markers of critical predictive nature?
Journal of clinical oncology : official journal of the American Society of Clinical Oncology Mar, 2004 | Pubmed ID: 14981108
Application of new in situ hybridization probes for Ku70 and Ku80 in tissue microarrays of paraffin-embedded malignant melanomas: correlation with immunohistochemical analysis.
Human pathology Feb, 2004 | Pubmed ID: 14991539
Decreased retinoid X receptor-alpha protein expression in basal cells occurs in the early stage of human prostate cancer development.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology Mar, 2004 | Pubmed ID: 15006913
Inhibition of orthotopic human bladder tumor growth by lentiviral gene transfer of endostatin.
Clinical cancer research : an official journal of the American Association for Cancer Research Mar, 2004 | Pubmed ID: 15014038
Survival signalling by Akt and eIF4E in oncogenesis and cancer therapy.
Nature Mar, 2004 | Pubmed ID: 15029198
The translation factor eIF-4E promotes tumor formation and cooperates with c-Myc in lymphomagenesis.
Nature medicine May, 2004 | Pubmed ID: 15098029
Altered expression and new mutations in DNA mismatch repair genes MLH1 and MSH2 in melanoma brain metastases.
Anticancer research Mar-Apr, 2004 | Pubmed ID: 15161053
High-resolution characterization of the pancreatic adenocarcinoma genome.
Proceedings of the National Academy of Sciences of the United States of America Jun, 2004 | Pubmed ID: 15199222
Hyperphosphorylation of pRb: a mechanism for RB tumour suppressor pathway inactivation in bladder cancer.
The Journal of pathology Jul, 2004 | Pubmed ID: 15221935
Analysis of adenomatous polyposis coli gene expression, APC locus-microsatellite instability and APC promoter methylation in the progression of melanocytic tumours.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc Dec, 2004 | Pubmed ID: 15257316
Comparison of DNA ploidy status and DNA ploidy-related parameters in malignant melanoma tissue microarrays and full sections.
Human pathology Jul, 2004 | Pubmed ID: 15257554
Caenorhabditis elegans ABL-1 antagonizes p53-mediated germline apoptosis after ionizing irradiation.
Nature genetics Aug, 2004 | Pubmed ID: 15273685
Preclinical validation of anti-TMEFF2-auristatin E-conjugated antibodies in the treatment of prostate cancer.
Molecular cancer therapeutics Aug, 2004 | Pubmed ID: 15299075
Rb inactivation promotes genomic instability by uncoupling cell cycle progression from mitotic control.
Nature Aug, 2004 | Pubmed ID: 15306814
Cytokeratin positivity in paraffin-embedded malignant melanomas: comparative study of KL1, A4 and Lu5 antibodies.
Anticancer research Sep-Oct, 2004 | Pubmed ID: 15510611
Genetic and immunophenotype analyses of TP53 in bladder cancer: TP53 alterations are associated with tumor progression.
Diagnostic molecular pathology : the American journal of surgical pathology, part B Dec, 2004 | Pubmed ID: 15538112
Glutathione S-transferase P1 Ile105Val polymorphism, cigarette smoking and prostate cancer.
Cancer detection and prevention , 2004 | Pubmed ID: 15542263
Racial disparity of epidermal growth factor receptor expression in prostate cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology Dec, 2004 | Pubmed ID: 15570072
Role of Dok-1 and Dok-2 in leukemia suppression.
The Journal of experimental medicine Dec, 2004 | Pubmed ID: 15611295
Application of in situ hybridization probes for MLH-1 and MSH-2 in tissue microarrays of paraffin-embedded malignant melanomas: correlation with immunohistochemistry and tumor stage.
Human pathology Dec, 2004 | Pubmed ID: 15619215
Molecular profiling of tumor progression in head and neck cancer.
Archives of otolaryngology--head & neck surgery Jan, 2005 | Pubmed ID: 15655179
Role of the proto-oncogene Pokemon in cellular transformation and ARF repression.
Nature Jan, 2005 | Pubmed ID: 15662416
Safety and biologic activity of intravenous BCL-2 antisense oligonucleotide (G3139) and taxane chemotherapy in patients with advanced cancer.
Applied immunohistochemistry & molecular morphology : AIMM / official publication of the Society for Applied Immunohistochemistry Mar, 2005 | Pubmed ID: 15722787
Celecoxib inhibits prostate cancer growth: evidence of a cyclooxygenase-2-independent mechanism.
Clinical cancer research : an official journal of the American Association for Cancer Research Mar, 2005 | Pubmed ID: 15756026
p73beta-Mediated apoptosis requires p57kip2 induction and IEX-1 inhibition.
Cancer research Mar, 2005 | Pubmed ID: 15781630
Drg1 expression in 131 colorectal liver metastases: correlation with clinical variables and patient outcomes.
Clinical cancer research : an official journal of the American Association for Cancer Research May, 2005 | Pubmed ID: 15867226
A phase I clinical trial of the sequential combination of irinotecan followed by flavopiridol.
Clinical cancer research : an official journal of the American Association for Cancer Research May, 2005 | Pubmed ID: 15897584
A microRNA polycistron as a potential human oncogene.
Nature Jun, 2005 | Pubmed ID: 15944707
Genetic analysis of Pten and Tsc2 functional interactions in the mouse reveals asymmetrical haploinsufficiency in tumor suppression.
Genes & development Aug, 2005 | Pubmed ID: 16027168
Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis.
Nature Aug, 2005 | Pubmed ID: 16079851
Cytokeratin expression correlates with aneuploidy in cytological specimens of melanoma metastases.
Anticancer research Jul-Aug, 2005 | Pubmed ID: 16080528
Expression of p63 in diffuse large B-cell lymphoma.
Applied immunohistochemistry & molecular morphology : AIMM / official publication of the Society for Applied Immunohistochemistry Sep, 2005 | Pubmed ID: 16082248
Evasion of the p53 tumour surveillance network by tumour-derived MYC mutants.
Nature Aug, 2005 | Pubmed ID: 16094360
Gene expression profiling in single cells within tissue.
Nature methods Sep, 2005 | Pubmed ID: 16118636
A novel multiplexing, polymerase chain reaction-based assay for the analysis of chromosome 18q status in colorectal cancer.
The Journal of molecular diagnostics : JMD Oct, 2005 | Pubmed ID: 16237217
Tobacco smoking, GSTP1 polymorphism, and bladder carcinoma.
Cancer Dec, 2005 | Pubmed ID: 16240451
Relationship of nm23 expression to proliferation and prognosis in malignant melanomas of the oral cavity.
In vivo (Athens, Greece) Nov-Dec, 2005 | Pubmed ID: 16277028
Proposal of a new grading system for malignant fibrous histiocytomas.
Anticancer research Nov-Dec, 2005 | Pubmed ID: 16309231
A novel logistic model based on clinicopathological features predicts microsatellite instability in colorectal carcinomas.
Diagnostic molecular pathology : the American journal of surgical pathology, part B Dec, 2005 | Pubmed ID: 16319691
[Molecular protocol for HER2/neu analysis in breast carcinoma].
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico Dec, 2005 | Pubmed ID: 16373062
Differential exoprotease activities confer tumor-specific serum peptidome patterns.
The Journal of clinical investigation Jan, 2006 | Pubmed ID: 16395409
Profiling bladder cancer using targeted antibody arrays.
The American journal of pathology Jan, 2006 | Pubmed ID: 16400012
Amplification of CDK4 and MDM2 in malignant melanoma.
Genes, chromosomes & cancer May, 2006 | Pubmed ID: 16419059
Defining molecular profiles of poor outcome in patients with invasive bladder cancer using oligonucleotide microarrays.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology Feb, 2006 | Pubmed ID: 16432078
Loss of Ku70/Ku80 expression occurs more frequently in hereditary than in sporadic colorectal tumors. Tissue microarray study.
Human pathology Apr, 2006 | Pubmed ID: 16564919
Identification of a tumour suppressor network opposing nuclear Akt function.
Nature May, 2006 | Pubmed ID: 16680151
Autocrine PDGFR signaling promotes mammary cancer metastasis.
The Journal of clinical investigation Jun, 2006 | Pubmed ID: 16741576
Identification and validation of oncogenes in liver cancer using an integrative oncogenomic approach.
Cell Jun, 2006 | Pubmed ID: 16814713
Comparative oncogenomics identifies NEDD9 as a melanoma metastasis gene.
Cell Jun, 2006 | Pubmed ID: 16814714
Altered expression of DNA double-strand repair genes Ku70 and Ku80 in carcinomas of the oral cavity.
Anticancer research May-Jun, 2006 | Pubmed ID: 16827151
Analysis of DNA mismatch repair gene expression and mutations in thyroid tumours.
Anticancer research May-Jun, 2006 | Pubmed ID: 16827152
Determinants of sensitivity and resistance to rapamycin-chemotherapy drug combinations in vivo.
Cancer research Aug, 2006 | Pubmed ID: 16885364
PML inhibits HIF-1alpha translation and neoangiogenesis through repression of mTOR.
Nature Aug, 2006 | Pubmed ID: 16915281
Evaluation of Ki67, p53 and angiogenesis in patients enrolled in a randomized study of neoadjuvant chemotherapy with or without cystectomy: a Southwest Oncology Group Study.
Oncology reports Oct, 2006 | Pubmed ID: 16969498
Alterations of the retinoblastoma and p16 pathway correlate with promoter methylation in malignant fibrous histiocytomas.
Anticancer research Sep-Oct, 2006 | Pubmed ID: 17094467
Mad2 overexpression promotes aneuploidy and tumorigenesis in mice.
Cancer cell Jan, 2007 | Pubmed ID: 17189715
Technology insight: will systems pathology replace the pathologist?
Nature clinical practice. Urology Jan, 2007 | Pubmed ID: 17211424
NEDD4-1 is a proto-oncogenic ubiquitin ligase for PTEN.
Cell Jan, 2007 | Pubmed ID: 17218260
Ubiquitination regulates PTEN nuclear import and tumor suppression.
Cell Jan, 2007 | Pubmed ID: 17218261
Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas.
Nature Feb, 2007 | Pubmed ID: 17251933
Hyperactivation of Ha-ras oncogene, but not Ink4a/Arf deficiency, triggers bladder tumorigenesis.
The Journal of clinical investigation Feb, 2007 | Pubmed ID: 17256055
Relation between human papillomavirus positivity and p16 expression in head and neck carcinomas--a tissue microarray study.
Anticancer research Jan-Feb, 2007 | Pubmed ID: 17352245
Role of the chromobox protein CBX7 in lymphomagenesis.
Proceedings of the National Academy of Sciences of the United States of America Mar, 2007 | Pubmed ID: 17374722
Molecular alterations associated with bladder cancer progression.
Seminars in oncology Apr, 2007 | Pubmed ID: 17382791
The AKT-mTOR pathway plays a critical role in the development of leiomyosarcomas.
Nature medicine Jun, 2007 | Pubmed ID: 17496901
A polymorphism in HDM2 (SNP309) associates with early onset in superficial tumors, TP53 mutations, and poor outcome in invasive bladder cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research Jun, 2007 | Pubmed ID: 17545525
Prognostic significance of p27Kip1 expression in bladder cancer.
BJU international Aug, 2007 | Pubmed ID: 17555476
Improved prediction of prostate cancer recurrence through systems pathology.
The Journal of clinical investigation Jul, 2007 | Pubmed ID: 17557117
Tissue-specific and reversible RNA interference in transgenic mice.
Nature genetics Jul, 2007 | Pubmed ID: 17572676
Highly efficient gene delivery for bladder cancers by intravesically administered replication-competent retroviral vectors.
Clinical cancer research : an official journal of the American Association for Cancer Research Aug, 2007 | Pubmed ID: 17671137
Identification of S664 TSC2 phosphorylation as a marker for extracellular signal-regulated kinase mediated mTOR activation in tuberous sclerosis and human cancer.
Cancer research Aug, 2007 | Pubmed ID: 17671177
Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia.
Nature medicine Oct, 2007 | Pubmed ID: 17873882
Declining p53 function in the aging process: a possible mechanism for the increased tumor incidence in older populations.
Proceedings of the National Academy of Sciences of the United States of America Oct, 2007 | Pubmed ID: 17921246
Somatic cell type specific gene transfer reveals a tumor-promoting function for p21(Waf1/Cip1).
The EMBO journal Nov, 2007 | Pubmed ID: 17948060
Derivation of sarcomas from mesenchymal stem cells via inactivation of the Wnt pathway.
The Journal of clinical investigation Nov, 2007 | Pubmed ID: 17948129
Identification of PHLPP1 as a tumor suppressor reveals the role of feedback activation in PTEN-mutant prostate cancer progression.
Cancer cell Aug, 2011 | Pubmed ID: 21840483
Genomic and proteomic profiles reveal the association of gelsolin to TP53 status and bladder cancer progression.
The American journal of pathology Nov, 2007 | Pubmed ID: 17982131
Bax and Bak do not exhibit functional redundancy in mediating radiation-induced endothelial apoptosis in the intestinal mucosa.
International journal of radiation oncology, biology, physics Mar, 2008 | Pubmed ID: 18191336
A context dependent role for Wnt signaling in tumorigenesis and stem cells.
Cell cycle (Georgetown, Tex.) Mar, 2008 | Pubmed ID: 18239459
TREK-1 is a novel molecular target in prostate cancer.
Cancer research Feb, 2008 | Pubmed ID: 18281496
A developmental model of sarcomagenesis defines a differentiation-based classification for liposarcomas.
The American journal of pathology Apr, 2008 | Pubmed ID: 18310505
Gli activity correlates with tumor grade in platelet-derived growth factor-induced gliomas.
Cancer research Apr, 2008 | Pubmed ID: 18381430
DLC1 is a chromosome 8p tumor suppressor whose loss promotes hepatocellular carcinoma.
Genes & development Jun, 2008 | Pubmed ID: 18519636
Chk2 suppresses the oncogenic potential of DNA replication-associated DNA damage.
Molecular cell Jul, 2008 | Pubmed ID: 18614044
Aberrant Rheb-mediated mTORC1 activation and Pten haploinsufficiency are cooperative oncogenic events.
Genes & development Aug, 2008 | Pubmed ID: 18708577
Systems pathology approach for the prediction of prostate cancer progression after radical prostatectomy.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology Aug, 2008 | Pubmed ID: 18711180
Targeting AKT/mTOR and ERK MAPK signaling inhibits hormone-refractory prostate cancer in a preclinical mouse model.
The Journal of clinical investigation Sep, 2008 | Pubmed ID: 18725989
Molecular alterations associated with bladder cancer initiation and progression.
Scandinavian journal of urology and nephrology. Supplementum Sep, 2008 | Pubmed ID: 18815930
Associations between variants of the 8q24 chromosome and nine smoking-related cancer sites.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology Nov, 2008 | Pubmed ID: 18990762
Alveolar rhabdomyosarcoma: is the cell of origin a mesenchymal stem cell?
Cancer letters Jul, 2009 | Pubmed ID: 19008039
Comparison of models to predict clinical failure after radical prostatectomy.
Cancer Jan, 2009 | Pubmed ID: 19025977
p53 is localized to a sub-nucleolar compartment after proteasomal inhibition in an energy-dependent manner.
Journal of cell science Dec, 2008 | Pubmed ID: 19033390
Identification of PMF1 methylation in association with bladder cancer progression.
Clinical cancer research : an official journal of the American Association for Cancer Research Dec, 2008 | Pubmed ID: 19088041
Gamma-secretase inhibitors reverse glucocorticoid resistance in T cell acute lymphoblastic leukemia.
Nature medicine Jan, 2009 | Pubmed ID: 19098907
Differential requirement of mTOR in postmitotic tissues and tumorigenesis.
Science signaling , 2009 | Pubmed ID: 19176516
ETS rearrangements and prostate cancer initiation.
Nature Feb, 2009 | Pubmed ID: 19212347
Correlation of MR imaging and MR spectroscopic imaging findings with Ki-67, phospho-Akt, and androgen receptor expression in prostate cancer.
Radiology Mar, 2009 | Pubmed ID: 19244047
Inactivation of p53 and Pten promotes invasive bladder cancer.
Genes & development Mar, 2009 | Pubmed ID: 19261747
A systems pathology model for predicting overall survival in patients with refractory, advanced non-small-cell lung cancer treated with gefitinib.
European journal of cancer (Oxford, England : 1990) May, 2009 | Pubmed ID: 19272767
Aberrant ERG expression cooperates with loss of PTEN to promote cancer progression in the prostate.
Nature genetics May, 2009 | Pubmed ID: 19396168
Prediction of prostate cancer recurrence using magnetic resonance imaging and molecular profiles.
Clinical cancer research : an official journal of the American Association for Cancer Research Jun, 2009 | Pubmed ID: 19435838
Personalized prediction of tumor response and cancer progression on prostate needle biopsy.
The Journal of urology Jul, 2009 | Pubmed ID: 19450827
Cyfip1 is a putative invasion suppressor in epithelial cancers.
Cell Jun, 2009 | Pubmed ID: 19524508
Systems pathology: a paradigm shift in the practice of diagnostic and predictive pathology.
Cancer Jul, 2009 | Pubmed ID: 19544549
3-Phosphoinositide-dependent kinase 1 potentiates upstream lesions on the phosphatidylinositol 3-kinase pathway in breast carcinoma.
Cancer research Aug, 2009 | Pubmed ID: 19602588
Androgen receptor expression is associated with prostate cancer-specific survival in castrate patients with metastatic disease.
BJU international Feb, 2010 | Pubmed ID: 19624594
MFH classification: differentiating undifferentiated pleomorphic sarcoma in the 21st Century.
Expert review of anticancer therapy Aug, 2009 | Pubmed ID: 19671033
The N-Myc-DLL3 cascade is suppressed by the ubiquitin ligase Huwe1 to inhibit proliferation and promote neurogenesis in the developing brain.
Developmental cell Aug, 2009 | Pubmed ID: 19686682
Intravesical delivery of rapamycin suppresses tumorigenesis in a mouse model of progressive bladder cancer.
Cancer prevention research (Philadelphia, Pa.) Dec, 2009 | Pubmed ID: 19952358
Overexpression of phospho-eIF4E is associated with survival through AKT pathway in non-small cell lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research Jan, 2010 | Pubmed ID: 20008839
miR-19 is a key oncogenic component of mir-17-92.
Genes & development Dec, 2009 | Pubmed ID: 20008935
Single nucleotide polymorphisms of 8 inflammation-related genes and their associations with smoking-related cancers.
International journal of cancer. Journal international du cancer Nov, 2010 | Pubmed ID: 20112337
PHF6 mutations in T-cell acute lymphoblastic leukemia.
Nature genetics Apr, 2010 | Pubmed ID: 20228800
Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence.
Nature Mar, 2010 | Pubmed ID: 20237562
Galectin-3 expression is associated with bladder cancer progression and clinical outcome.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine Aug, 2010 | Pubmed ID: 20401558
Associations between NBS1 polymorphisms, haplotypes and smoking-related cancers.
Carcinogenesis Jul, 2010 | Pubmed ID: 20478923
Integrative genome comparison of primary and metastatic melanomas.
PloS one , 2010 | Pubmed ID: 20520718
Molecular pathways of urothelial development and bladder tumorigenesis.
Urologic oncology Jul-Aug, 2010 | Pubmed ID: 20610278
Impact of stromal sensitivity on radiation response of tumors implanted in SCID hosts revisited.
Cancer research Oct, 2010 | Pubmed ID: 20924105
Association of nuclear localization of a long interspersed nuclear element-1 protein in breast tumors with poor prognostic outcomes.
Genes & cancer Feb, 2010 | Pubmed ID: 20948976
The TLX1 oncogene drives aneuploidy in T cell transformation.
Nature medicine Nov, 2010 | Pubmed ID: 20972433
Disruption of a Sirt1-dependent autophagy checkpoint in the prostate results in prostatic intraepithelial neoplasia lesion formation.
Cancer research Feb, 2011 | Pubmed ID: 21189328
Hydrophilic agarose macrobead cultures select for outgrowth of carcinoma cell populations that can restrict tumor growth.
Cancer research Feb, 2011 | Pubmed ID: 21266362
Three-dimensional culture of mouse renal carcinoma cells in agarose macrobeads selects for a subpopulation of cells with cancer stem cell or cancer progenitor properties.
Cancer research Feb, 2011 | Pubmed ID: 21266363
CpG ODN, Toll like receptor (TLR)-9 agonist, inhibits metastatic colon adenocarcinoma in a murine hepatic tumor model.
The Journal of surgical research May, 2012 | Pubmed ID: 21324492
Distinct expression profiles of p63 variants during urothelial development and bladder cancer progression.
The American journal of pathology Mar, 2011 | Pubmed ID: 21356385
Alternate PAX3 and PAX7 C-terminal isoforms in myogenic differentiation and sarcomagenesis.
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico Mar, 2011 | Pubmed ID: 21421465
KISS1 methylation and expression as tumor stratification biomarkers and clinical outcome prognosticators for bladder cancer patients.
The American journal of pathology Aug, 2011 | Pubmed ID: 21683672
A comparison of the outcomes of neoadjuvant and adjuvant chemotherapy for clinical T2-T4aN0-N2M0 bladder cancer.
Cancer Jan, 2012 | Pubmed ID: 21717438
A systems-based modelling approach using transurethral resection of the prostate (TURP) specimens yielded incremental prognostic significance to Gleason when predicting long-term outcome in men with localized prostate cancer.
BJU international Jan, 2012 | Pubmed ID: 21733075
Postoperative systems models more accurately predict risk of significant disease progression than standard risk groups and a 10-year postoperative nomogram: potential impact on the receipt of adjuvant therapy after surgery.
BJU international Jan, 2012 | Pubmed ID: 21771247
A Role for PML in Innate Immunity.
Genes & cancer Jan, 2011 | Pubmed ID: 21779477
Predictive value of microtubule associated proteins tau and stathmin in patients with nonmuscle invasive bladder cancer receiving adjuvant intravesical taxane therapy.
The Journal of urology Nov, 2011 | Pubmed ID: 21944130
Anatomical features of the urethra and urinary bladder catheterization in female mice and rats. An essential translational tool.
Acta cirúrgica brasileira / Sociedade Brasileira para Desenvolvimento Pesquisa em Cirurgia , 2011 | Pubmed ID: 22030824
Personalized approach to prostate cancer prognosis.
Archivos españoles de urología Oct, 2011 | Pubmed ID: 22052759
PPARγ agonists enhance ET-743-induced adipogenic differentiation in a transgenic mouse model of myxoid round cell liposarcoma.
The Journal of clinical investigation Mar, 2012 | Pubmed ID: 22293175
Mouse models of human bladder cancer as a tool for drug discovery.
Current protocols in pharmacology / editorial board, S.J. Enna (editor-in-chief) ... [et al.] Jun, 2010 | Pubmed ID: 22294368
PAX7-FKHR fusion gene inhibits myogenic differentiation via NF-kappaB upregulation.
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico Mar, 2012 | Pubmed ID: 22374423
miR-143, miR-222, and miR-452 are useful as tumor stratification and noninvasive diagnostic biomarkers for bladder cancer.
The American journal of pathology May, 2012 | Pubmed ID: 22426337
Perioperative polyphenon E, a green tea extract, does not affect the wound complication rate in mice after sham laparotomy yet has an inhibitory effect on wound healing.
Surgical innovation Dec, 2012 | Pubmed ID: 22431911
Translocation renal cell carcinomas in adults: a single-institution experience.
The American journal of surgical pathology May, 2012 | Pubmed ID: 22446944
A BAC-based transgenic mouse specifically expresses an inducible Cre in the urothelium.
PloS one , 2012 | Pubmed ID: 22496911
Preclinical analysis of the γ-secretase inhibitor PF-03084014 in combination with glucocorticoids in T-cell acute lymphoblastic leukemia.
Molecular cancer therapeutics Jul, 2012 | Pubmed ID: 22504949
Targeting nonclassical oncogenes for therapy in T-ALL.
Cancer cell Apr, 2012 | Pubmed ID: 22516257
Suppression of acquired docetaxel resistance in prostate cancer through depletion of notch- and hedgehog-dependent tumor-initiating cells.
Cancer cell Sep, 2012 | Pubmed ID: 22975379
MAGE-A3 is highly expressed in a subset of colorectal cancer patients.
Cancer immunity , 2012 | Pubmed ID: 23390371
A common MicroRNA signature consisting of miR-133a, miR-139-3p, and miR-142-3p clusters bladder carcinoma in situ with normal umbrella cells.
The American journal of pathology Apr, 2013 | Pubmed ID: 23410519
Predicting high-risk disease using tissue biomarkers.
Current opinion in urology May, 2013 | Pubmed ID: 23478499
Compound In Vivo Inactivation of Pml and p53 Uncovers a Functional Interaction in Angiosarcoma Suppression.
Genes & cancer Sep, 2012 | Pubmed ID: 23486996
Loss of PML cooperates with mutant p53 to drive more aggressive cancers in a gender-dependent manner.
Cell cycle (Georgetown, Tex.) Jun, 2013 | Pubmed ID: 23656786
Dual Pten/Tp53 suppression promotes sarcoma progression by activating Notch signaling.
The American journal of pathology Jun, 2013 | Pubmed ID: 23708211
A co-clinical approach identifies mechanisms and potential therapies for androgen deprivation resistance in prostate cancer.
Nature genetics Jul, 2013 | Pubmed ID: 23727860
Zbtb7a suppresses prostate cancer through repression of a Sox9-dependent pathway for cellular senescence bypass and tumor invasion.
Nature genetics Jul, 2013 | Pubmed ID: 23727861
Direct reversal of glucocorticoid resistance by AKT inhibition in acute lymphoblastic leukemia.
Cancer cell Dec, 2013 | Pubmed ID: 24291004
RapidCaP, a Novel GEM Model for Metastatic Prostate Cancer Analysis and Therapy, Reveals Myc as a Driver of Pten-Mutant Metastasis.
Cancer discovery Mar, 2014 | Pubmed ID: 24444712
Genomic analysis in active surveillance: predicting high-risk disease using tissue biomarkers.
Current opinion in urology May, 2014 | Pubmed ID: 24625431
The miR-424(322)/503 cluster orchestrates remodeling of the epithelium in the involuting mammary gland.
Genes & development Apr, 2014 | Pubmed ID: 24636986
Defining the role of CD2 in disease progression and overall survival among patients with completely resected stage-II to -III cutaneous melanoma.
Journal of the American Academy of Dermatology Jun, 2014 | Pubmed ID: 24698703
FBXW7 mutations in melanoma and a new therapeutic paradigm.
Journal of the National Cancer Institute Jun, 2014 | Pubmed ID: 24838835
Characterization of desmoglein expression in the normal prostatic gland. Desmoglein 2 is an independent prognostic factor for aggressive prostate cancer.
PloS one , 2014 | Pubmed ID: 24896103
A NOTCH1-driven MYC enhancer promotes T cell development, transformation and acute lymphoblastic leukemia.
Nature medicine Oct, 2014 | Pubmed ID: 25194570
Bladder cancers arise from distinct urothelial sub-populations.
Nature cell biology Oct, 2014 | Pubmed ID: 25218638
The microRNA 424/503 cluster reduces CDC25A expression during cell cycle arrest imposed by transforming growth factor β in mammary epithelial cells.
Molecular and cellular biology Dec, 2014 | Pubmed ID: 25266660
Overcoming tumor heterogeneity in the molecular diagnosis of urological cancers.
Expert review of molecular diagnostics Nov, 2014 | Pubmed ID: 25327491
Biomarkers for bladder cancer management: present and future.
American journal of clinical and experimental urology , 2014 | Pubmed ID: 25374904
ΔNp63 expression is a protective factor of progression in clinical high grade T1 bladder cancer.
The Journal of urology Apr, 2015 | Pubmed ID: 25444981
Loss of Sirt1 promotes prostatic intraepithelial neoplasia, reduces mitophagy, and delays PARK2 translocation to mitochondria.
The American journal of pathology Jan, 2015 | Pubmed ID: 25529796
Limited miR-17-92 overexpression drives hematologic malignancies.
Leukemia research Mar, 2015 | Pubmed ID: 25597017
Massive parallel sequencing uncovers actionable FGFR2-PPHLN1 fusion and ARAF mutations in intrahepatic cholangiocarcinoma.
Nature communications , 2015 | Pubmed ID: 25608663
A genetic platform to model sarcomagenesis from primary adult mesenchymal stem cells.
Cancer discovery Apr, 2015 | Pubmed ID: 25614485
Suppression of CHK1 by ETS Family Members Promotes DNA Damage Response Bypass and Tumorigenesis.
Cancer discovery May, 2015 | Pubmed ID: 25653093
A targetable GATA2-IGF2 axis confers aggressiveness in lethal prostate cancer.
Cancer cell Feb, 2015 | Pubmed ID: 25670080
Methodological aspects of the molecular and histological study of prostate cancer: focus on PTEN.
Methods (San Diego, Calif.) May, 2015 | Pubmed ID: 25697760
MYC Drives Pten/Trp53-Deficient Proliferation and Metastasis due to IL6 Secretion and AKT Suppression via PHLPP2.
Cancer discovery Jun, 2015 | Pubmed ID: 25829425
PI3K/AKT pathway regulates E-cadherin and Desmoglein 2 in aggressive prostate cancer.
Cancer medicine Aug, 2015 | Pubmed ID: 26033689
Inhibition of the autocrine IL-6-JAK2-STAT3-calprotectin axis as targeted therapy for HR-/HER2+ breast cancers.
Genes & development Aug, 2015 | Pubmed ID: 26227964
Expression of the cancer testis antigen IGF2BP3 in colorectal cancers; IGF2BP3 holds promise as a specific immunotherapy target.
Oncoscience , 2015 | Pubmed ID: 26244168
Metabolic reprogramming induces resistance to anti-NOTCH1 therapies in T cell acute lymphoblastic leukemia.
Nature medicine Oct, 2015 | Pubmed ID: 26390244
H-RAS mutation is a key molecular feature of pediatric urothelial bladder cancer. A detailed report of three cases.
Journal of pediatric urology Apr, 2016 | Pubmed ID: 26522772
Immunopathologic Assessment of PTEN Expression.
Methods in molecular biology (Clifton, N.J.) , 2016 | Pubmed ID: 27033068
Enrichment of Cells with Cancer Stem Cell-Like Markers in Relapses of Chemoresistant Patients with Locally Advanced Head and Neck Squamous Cell Carcinoma.
Oncology , 2016 | Pubmed ID: 27077749
Urachal Carcinoma Shares Genomic Alterations with Colorectal Carcinoma and May Respond to Epidermal Growth Factor Inhibition.
European urology Nov, 2016 | Pubmed ID: 27178450
The metabolic co-regulator PGC1α suppresses prostate cancer metastasis.
Nature cell biology 06, 2016 | Pubmed ID: 27214280
Protein Profiling of Bladder Urothelial Cell Carcinoma.
PloS one , 2016 | Pubmed ID: 27626805
Ornithine Decarboxylase Is Sufficient for Prostate Tumorigenesis via Androgen Receptor Signaling.
The American journal of pathology Dec, 2016 | Pubmed ID: 27770613
The role of GATA2 in lethal prostate cancer aggressiveness.
Nature reviews. Urology Jan, 2017 | Pubmed ID: 27872477
Reappraising hyalinizing clear cell carcinoma: A population-based study with molecular confirmation.
Head & neck Mar, 2017 | Pubmed ID: 27898192
Implementation of a Precision Pathology Program Focused on Oncology-Based Prognostic and Predictive Outcomes.
Molecular diagnosis & therapy Apr, 2017 | Pubmed ID: 28000172
The nuclear transport receptor Importin-11 is a tumor suppressor that maintains PTEN protein.
The Journal of cell biology Mar, 2017 | Pubmed ID: 28193700
miR-424(322)/503 is a breast cancer tumor suppressor whose loss promotes resistance to chemotherapy.
Genes & development Mar, 2017 | Pubmed ID: 28404630
Targeting sarcoma tumor-initiating cells through differentiation therapy.
Stem cell research May, 2017 | Pubmed ID: 28433655
PTEN counteracts FBXL2 to promote IP3R3- and Ca(2+)-mediated apoptosis limiting tumour growth.
Nature Jun, 2017 | Pubmed ID: 28614300
mTORC1-dependent AMD1 regulation sustains polyamine metabolism in prostate cancer.
Nature Jul, 2017 | Pubmed ID: 28658205
Erratum: The metabolic co-regulator PGC1α suppresses prostate cancer metastasis.
Nature cell biology Jun, 2017 | Pubmed ID: 28659639
Myocardial Amyloid Quantification with Look-Locker Magnetic Resonance Sequence in Cardiac Amyloidosis. Diagnostic Accuracy in Clinical Practice and Histological Validation.
Journal of cardiac failure Aug, 2017 | Pubmed ID: 28801077