Melissa McKane

Early myocardial function affects endocardial cushion development in zebrafish.

A mammalian actin substitution in yeast actin (H372R) causes a suppressible mitochondria/vacuole phenotype.

Effect of the substitution of muscle actin-specific subdomain 1 and 2 residues in yeast actin on actin function.

Control of the ability of profilin to bind and facilitate nucleotide exchange from G-actin.

Role of intermonomer ionic bridges in the stabilization of the actin filament.

A potential yeast actin allosteric conduit dependent on hydrophobic core residues val-76 and trp-79.

Allele-specific effects of thoracic aortic aneurysm and dissection alpha-smooth muscle actin mutations on actin function.

Mutant profilin suppresses mutant actin-dependent mitochondrial phenotype in Saccharomyces cerevisiae.

The W-loop of alpha-cardiac actin is critical for heart function and endocardial cushion morphogenesis in zebrafish.

Thoracic aortic aneurysm (TAAD)-causing mutation in actin affects formin regulation of polymerization.

Actin depolymerization under force is governed by lysine 113:glutamic acid 195-mediated catch-slip bonds.

Functional analysis of a de novo ACTB mutation in a patient with atypical Baraitser-Winter syndrome.

Importance of a Lys113-Glu195 intermonomer ionic bond in F-actin stabilization and regulation by yeast formins Bni1p and Bnr1p.