Institute for Regenerative Medicine at Scott & White Hospital,
Molecular and Cellular Medicine
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The Wnt signaling inhibitor dickkopf-1 is required for reentry into the cell cycle of human adult stem cells from bone marrow.
The Journal of biological chemistry Jul, 2003 | Pubmed ID: 12740383
One strategy for cell and gene therapy: harnessing the power of adult stem cells to repair tissues.
Proceedings of the National Academy of Sciences of the United States of America Sep, 2003 | Pubmed ID: 13679583
Internalized antigens must be removed to prepare hypoimmunogenic mesenchymal stem cells for cell and gene therapy.
Molecular therapy : the journal of the American Society of Gene Therapy May, 2004 | Pubmed ID: 15120336
An Alizarin red-based assay of mineralization by adherent cells in culture: comparison with cetylpyridinium chloride extraction.
Analytical biochemistry Jun, 2004 | Pubmed ID: 15136169
Dkk-1-derived synthetic peptides and lithium chloride for the control and recovery of adult stem cells from bone marrow.
The Journal of biological chemistry Jan, 2005 | Pubmed ID: 15504735
Non-hematopoietic bone marrow stem cells: molecular control of expansion and differentiation.
Experimental cell research Jun, 2005 | Pubmed ID: 15925588
How Wnt signaling affects bone repair by mesenchymal stem cells from the bone marrow.
Annals of the New York Academy of Sciences May, 2005 | Pubmed ID: 15965110
Adult bone marrow stem/progenitor cells (MSCs) are preconditioned by microenvironmental "niches" in culture: a two-stage hypothesis for regulation of MSC fate.
Science's STKE : signal transduction knowledge environment Jul, 2005 | Pubmed ID: 16046665
A crosstalk between myeloma cells and marrow stromal cells stimulates production of DKK1 and interleukin-6: a potential role in the development of lytic bone disease and tumor progression in multiple myeloma.
Stem cells (Dayton, Ohio) Apr, 2006 | Pubmed ID: 16293576
Enhanced engraftment of mesenchymal stem cells in a cutaneous wound model by culture in allogenic species-specific serum and administration in fibrin constructs.
Stem cells (Dayton, Ohio) Oct, 2006 | Pubmed ID: 16763199
The promise of canonical Wnt signaling modulators in enhancing bone repair.
Drug news & perspectives Oct, 2006 | Pubmed ID: 17160144
More progress defining the crosstalk between multiple myeloma and mesenchymal stem cells of the bone marrow.
Leukemia & lymphoma Oct, 2007 | Pubmed ID: 17917957
Leukemia inhibitory factor secretion is a predictor and indicator of early progenitor status in adult bone marrow stromal cells.
Tissue engineering. Part A Jan, 2009 | Pubmed ID: 18637760
The CD34-like protein PODXL and alpha6-integrin (CD49f) identify early progenitor MSCs with increased clonogenicity and migration to infarcted heart in mice.
Blood Jan, 2009 | Pubmed ID: 18818395
Pharmaceutical induction of ApoE secretion by multipotent mesenchymal stromal cells (MSCs).
BMC biotechnology , 2008 | Pubmed ID: 18823563
CD133 identifies a human bone marrow stem/progenitor cell sub-population with a repertoire of secreted factors that protect against stroke.
Molecular therapy : the journal of the American Society of Gene Therapy Nov, 2009 | Pubmed ID: 19690521
Pharmaceutical modulation of canonical Wnt signaling in multipotent stromal cells for improved osteoinductive therapy.
Proceedings of the National Academy of Sciences of the United States of America Mar, 2010 | Pubmed ID: 20150512
Pharmaceutical inhibition of glycogen synthetase kinase-3β reduces multiple myeloma-induced bone disease in a novel murine plasmacytoma xenograft model.
Blood Feb, 2011 | Pubmed ID: 21123822
Assays of osteogenic differentiation by cultured human mesenchymal stem cells.
Methods in molecular biology (Clifton, N.J.) , 2011 | Pubmed ID: 21431522
Potential of modulating Wnt signaling pathway toward the development of bone anabolic agent.
Current molecular pharmacology Jun, 2012 | Pubmed ID: 21787289
Human mesenchymal stem cell-derived matrices for enhanced osteoregeneration.
Science translational medicine May, 2012 | Pubmed ID: 22553253
Bone regeneration with osteogenically enhanced mesenchymal stem cells and their extracellular matrix proteins.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research Jan, 2015 | Pubmed ID: 25130615
MSCs derived from iPSCs with a modified protocol are tumor-tropic but have much less potential to promote tumors than bone marrow MSCs.
Proceedings of the National Academy of Sciences of the United States of America Jan, 2015 | Pubmed ID: 25548183