Takahide Nagase

Hyperoxia exaggerates bacterial dissemination and lethality in Pseudomonas aeruginosa pneumonia.

Airway hyperresponsiveness in transgenic mice overexpressing platelet activating factor receptor is mediated by an atropine-sensitive pathway.

A pivotal role of cytosolic phospholipase A(2) in bleomycin-induced pulmonary fibrosis.

Identification of multiple novel epididymis-specific beta-defensin isoforms in humans and mice.

Attenuation of antigen-induced airway hyperresponsiveness in CGRP-deficient mice.

Effects of obstructive sleep apnea on circulating ICAM-1, IL-8, and MCP-1.

Molecular mechanisms underlying human beta-defensin-2 gene expression in a human airway cell line (LC2/ad).

Platelet-activating factor receptor.

A potent inhibitor of cytosolic phospholipase A2, arachidonyl trifluoromethyl ketone, attenuates LPS-induced lung injury in mice.

New therapeutic key for cystic fibrosis: a role for lipoxins.

Platelet-activating factor receptor develops airway hyperresponsiveness independently of airway inflammation in a murine asthma model.

Voltage-gated sodium channel expressed in cultured human smooth muscle cells: involvement of SCN9A.

[Lipid mediators and pulmonary diseases].

[Recent progress in leukotriene research].

Acute and chronic effects of eicosapentaenoic acid on voltage-gated sodium channel expressed in cultured human bronchial smooth muscle cells.

Leukotriene D4 potentiates fibronectin-induced migration of human lung fibroblasts.

Absence of leukotriene B4 receptor 1 confers resistance to airway hyperresponsiveness and Th2-type immune responses.

Betaine improved restriction digestion.

[Respiratory disorders in the aged: in the present and future].

[How to activate clinical management of the aged patients using COPD guidelines?].

Beta-defensin overexpression induces progressive muscle degeneration in mice.

Adrenomedullin insufficiency increases allergen-induced airway hyperresponsiveness in mice.

The induction of H3K9 methylation by PIWIL4 at the p16Ink4a locus.

Prevention of postextubation laryngeal oedema.

A template for informed consent forms in medical examination and treatment: an intervention study.

Calcitonin gene-related peptide mediates acid-induced lung injury in mice.

[Clinical management of the aged patients with COPD].

Multiple renal cysts, urinary concentration defects, and pulmonary emphysematous changes in mice lacking TAZ.

Non-infectious bronchiolitis as an early pulmonary complication of hematopoietic stem cell transplantation.

Effect of dexamethasone on voltage-gated Na+ channel in cultured human bronchial smooth muscle cells.

Sequential and quantitative analysis of a murine model of elastase-induced emphysema.

Clarithromycin inhibits fibroblast migration.

[Chronic obstructive pulmonary disease (COPD)].

C-reactive protein modulates human lung fibroblast migration.

Thyroid transcription factor-1 inhibits transforming growth factor-beta-mediated epithelial-to-mesenchymal transition in lung adenocarcinoma cells.

Transcriptional coactivator with PDZ-binding motif is essential for normal alveolarization in mice.

Procaterol inhibits lung fibroblast migration.

Identification of G0S2 as a gene frequently methylated in squamous lung cancer by combination of in silico and experimental approaches.

Histamine stimulates human lung fibroblast migration.

Impact of DNA demethylation of the G0S2 gene on the transcription of G0S2 in squamous lung cancer cell lines with or without nuclear receptor agonists.

Amino acid residues critical for endoplasmic reticulum export and trafficking of platelet-activating factor receptor.

Tumor necrosis factor-alpha enhances both epithelial-mesenchymal transition and cell contraction induced in A549 human alveolar epithelial cells by transforming growth factor-beta1.

[Clinical and radiological features of tuberculous pneumonia in patients with emphysema].

Down-regulation of secreted lymphocyte antigen-6/urokinase-type plasminogen activator receptor-related peptide-1 (SLURP-1), an endogenous allosteric alpha7 nicotinic acetylcholine receptor modulator, in murine and human asthmatic conditions.

Treatment of PCR products with exonuclease I and heat-labile alkaline phosphatase improves the visibility of combined bisulfite restriction analysis.

[Case of sarcoidosis with squamous cell carcinoma which originated from solitary bronchial papilloma].

Simultaneous stimulation with TGF-β1 and TNF-α induces epithelial mesenchymal transition in bronchial epithelial cells.

Suppression of transforming growth factor β1 in lung alveolar epithelium-derived cells using adeno-associated virus type 2/5 vectors to carry short hairpin RNA.

Polymerase reaction without primers throughout for the reconstruction of full-length cDNA from products of rapid amplification of cDNA ends (RACE).

Genome structure-based screening identified epigenetically silenced microRNA associated with invasiveness in non-small-cell lung cancer.

Pulmonary features associated with being underweight in older men.

Pulmonary venous invasion, determined by chest computed tomographic scan, as a potential early indicator of zygomycosis infection: a case series.

CpG island methylation of microRNAs is associated with tumor size and recurrence of non-small-cell lung cancer.

[Pathophysiology of peripheral airway obstruction underlying COPD].

[Respiratory diseases in the elderly].

[The effects of macrolides (EM900, clarithromycin and azithromycin) on IL-17-induced IL-8 production by airway epithelial cells].

Oncology information on the Internet.

The role of CCR7 in allergic airway inflammation induced by house dust mite exposure.

Suppressive effects of a pyrazole derivative of curcumin on airway inflammation and remodeling.

Dynamic change in respiratory resistance during inspiratory and expiratory phases of tidal breathing in patients with chronic obstructive pulmonary disease.

Characterization of human lung cancer-associated fibroblasts in three-dimensional in vitro co-culture model.

Tumor necrosis factor superfamily member LIGHT induces epithelial-mesenchymal transition in A549 human alveolar epithelial cells.

MxA transcripts with distinct first exons and modulation of gene expression levels by single-nucleotide polymorphisms in human bronchial epithelial cells.

Differential effects of a common splice site polymorphism on the generation of OAS1 variants in human bronchial epithelial cells.

An integrated expression profiling reveals target genes of TGF-β and TNF-α possibly mediated by microRNAs in lung cancer cells.

[Management of chronic obstructive pulmonary disease in the elderly].

FER overexpression is associated with poor postoperative prognosis and cancer-cell survival in non-small cell lung cancer.

Infectious mediastinal lymphadenopathy after repeated transbronchial needle aspiration.

[Respiratory failure].

Effect of secreted lymphocyte antigen-6/urokinase-type plasminogen activator receptor-related peptide-1 (SLURP-1) on airway epithelial cells.

Detection of novel paraja ring finger 2-fer tyrosine kinase mRNA chimeras is associated with poor postoperative prognosis in non-small cell lung cancer.

Successful Treatment of Mediastinal Unicentric Castleman's Disease Using Video-Assisted Thoracoscopic Surgery with Preoperative Embolization.

Histamine induces human lung fibroblast-mediated collagen gel contraction via histamine H1 receptor.

Selective inhibitors of a PAF biosynthetic enzyme lysophosphatidylcholine acyltransferase 2.

An integrative analysis of the tumorigenic role of TAZ in human non-small cell lung cancer.

Novel swine model of transfusion-related acute lung injury.

Alternative polyadenylation is associated with lower expression of PABPN1 and poor prognosis in non-small cell lung cancer.

Differential knockdown of TGF-β ligands in a three-dimensional co-culture tumor- stromal interaction model of lung cancer.

Factors affecting mortality following emergency admission for chronic obstructive pulmonary disease.

Clinical features of 280 hospitalized patients with lymphangioleiomyomatosis in Japan.

Lymphotoxin β Receptor Signaling Induces IL-8 Production in Human Bronchial Epithelial Cells.

Paradoxical association between body mass index and in-hospital mortality in elderly patients with chronic obstructive pulmonary disease in Japan.

Oncogenic TPM3-ALK activation requires dimerization through the coiled-coil structure of TPM3.

Ovary-dependent emphysema augmentation and osteopontin induction in adult female mice.

Comparison of in-hospital mortality in patients with COPD, asthma and asthma-COPD overlap exacerbations.

Role of α1 and α2 chains of type IV collagen in early fibrotic lesions of idiopathic interstitial pneumonias and migration of lung fibroblasts.

Pulmonary Metastasis of Combined Hepatocellular and Cholangiocarcinoma: A Unique Radiographic Presentation with Air-space Consolidation Masquerading as Pneumonia and Primary Pulmonary Adenocarcinoma.

Oncogenic activity of BIRC2 and BIRC3 mutants independent of nuclear factor-κB-activating potential.

Comparison of clinical characteristics and outcomes between aspiration pneumonia and community-acquired pneumonia in patients with chronic obstructive pulmonary disease.

Histone methylation-mediated silencing of miR-139 enhances invasion of non-small-cell lung cancer.

Hippo and TGF-β interplay in the lung field.

Interleukin-17A and Toll-Like Receptor 3 Ligand Poly(I:C) Synergistically Induced Neutrophil Chemoattractant Production by Bronchial Epithelial Cells.

The chimeric transcript RUNX1-GLRX5: a biomarker for good postoperative prognosis in Stage IA non-small-cell lung cancer.

Nonspecific elevation of serum Aspergillus galactomannan antigen levels in patients with rheumatoid arthritis.

Fibroblast VEGF-receptor 1 expression as molecular target in periodontitis.

A case of Meigs' syndrome with preceding pericardial effusion in advance of pleural effusion.

TIM-3 is not essential for development of airway inflammation induced by house dust mite antigens.