Twan Lammers

Effect of physicochemical modification on the biodistribution and tumor accumulation of HPMA copolymers.

Synthesis and characterization of HE-24.8: a polymeric contrast agent for magnetic resonance angiography.

Effect of intratumoral injection on the biodistribution and the therapeutic potential of HPMA copolymer-based drug delivery systems.

Effect of radiotherapy and hyperthermia on the tumor accumulation of HPMA copolymer-based drug delivery systems.

Specific targeting of tumor angiogenesis by RGD-conjugated ultrasmall superparamagnetic iron oxide particles using a clinical 1.5-T magnetic resonance scanner.

Role of PP2Calpha in cell growth, in radio- and chemosensitivity, and in tumorigenicity.

Role of type 2C protein phosphatases in growth regulation and in cellular stress signaling.

Superparamagnetic iron oxide nanoparticles encapsulated in biodegradable thermosensitive polymeric micelles: toward a targeted nanomedicine suitable for image-guided drug delivery.

Simultaneous delivery of doxorubicin and gemcitabine to tumors in vivo using prototypic polymeric drug carriers.

Improving the efficacy of combined modality anticancer therapy using HPMA copolymer-based nanomedicine formulations.

HPMA copolymers: 30 years of advances.

Core-crosslinked polymeric micelles with controlled release of covalently entrapped doxorubicin.

Nanotheranostics and image-guided drug delivery: current concepts and future directions.

Gene silencing activity of siRNA polyplexes based on thiolated N,N,N-trimethylated chitosan.

Gene silencing activity of siRNA polyplexes based on biodegradable polymers.

HPMA-based polymer therapeutics improve the efficacy of surgery, of radiotherapy and of chemotherapy combinations.

Removable nanocoatings for siRNA polyplexes.

Nanobody-shell functionalized thermosensitive core-crosslinked polymeric micelles for active drug targeting.

SiRNA delivery with functionalized carbon nanotubes.

Interaction of liposomes with proteins measured by surface plasmon resonance correlates with their in vivo circulation time.

Photochemical internalization (PCI)-mediated enhancement of gene silencing efficiency of polymethacrylates and N,N,N-trimethylated chitosan (TMC) based siRNA polyplexes.

Theranostic nanomedicine.

FMN-coated fluorescent iron oxide nanoparticles for RCP-mediated targeting and labeling of metabolically active cancer and endothelial cells.

Physicochemical and biological aspects of macrophage-mediated drug targeting in anti-microbial therapy.

Iron oxide nanoparticle-containing microbubble composites as contrast agents for MR and ultrasound dual-modality imaging.

Reprint of "Nanobody--shell functionalized thermosensitive core-crosslinked polymeric micelles for active drug targeting".

Virtual elastic sphere processing enables reproducible quantification of vessel stenosis at CT and MR angiography.

MRI evaluation of the antitumor activity of paramagnetic liposomes loaded with prednisolone phosphate.

Macromolecular nanotheranostics for multimodal anticancer therapy.

Overcoming cellular multidrug resistance using classical nanomedicine formulations.

Liposomes as carriers for colchicine-derived prodrugs: vascular disrupting nanomedicines with tailorable drug release kinetics.

Polyplexes based on cationic polymers with strong nucleic acid binding properties.

Drug targeting to tumors: principles, pitfalls and (pre-) clinical progress.

Comparison of polymeric siRNA nanocarriers in a murine LPS-activated macrophage cell line: gene silencing, toxicity and off-target gene expression.

Nanomedicine formulations for combination therapies.

A polymeric colchicinoid prodrug with reduced toxicity and improved efficacy for vascular disruption in cancer therapy.

Double-edged role of the CXCL12/CXCR4 axis in experimental myocardial infarction.

Theranostic cRGD-BioShuttle Constructs Containing Temozolomide- and Cy7 For NIR-Imaging and Therapy.

Theranostic systems and strategies for monitoring nanomedicine-mediated drug targeting.

Drug targeting systems for inflammatory disease: one for all, all for one.

Fluorescent magnetoliposomes as a platform technology for functional and molecular MR and optical imaging.

Nanomedicine on the move: from monotherapeutic regimens to combination therapies.

Ultrasound microbubbles for molecular diagnosis, therapy, and theranostics.

MRI-assessed therapeutic effects of locally administered PLGA nanoparticles loaded with anti-inflammatory siRNA in a murine arthritis model.

Image-guided, targeted and triggered drug delivery to tumors using polymer-based microbubbles.

Drug delivery research in Europe.

Glucocorticoid-loaded core-cross-linked polymeric micelles with tailorable release kinetics for targeted therapy of rheumatoid arthritis.

BioShuttle Mobility in Living Cells Studied with High-Resolution FCS & CLSM Methodologies.

Personalized nanomedicine.

Screening of budesonide nanoformulations for treatment of inflammatory bowel disease in an inflamed 3D cell-culture model.

Riboflavin carrier protein-targeted fluorescent USPIO for the assessment of vascular metabolism in tumors.

Peptide-functionalized gold nanorods increase liver injury in hepatitis.

Combined treatment with recombinant tissue plasminogen activator and dexamethasone phosphate-containing liposomes improves neurological outcome and restricts lesion progression after embolic stroke in rats.

Noninvasive optical imaging of nanomedicine biodistribution.

Intrinsically active nanobody-modified polymeric micelles for tumor-targeted combination therapy.

Non-invasive imaging for studying anti-angiogenic therapy effects.

Elastin-based molecular MRI of liver fibrosis.

Smart drug delivery systems: back to the future vs. clinical reality.

Recent progress in nanomedicine: therapeutic, diagnostic and theranostic applications.

Nondestructive monitoring of tissue-engineered constructs.

Rhodamine-loaded intercellular adhesion molecule-1-targeted microbubbles for dual-modality imaging under controlled shear stresses.

Multidrug resistance: Physiological principles and nanomedical solutions.

In Vivo Nanotoxicity Testing using the Zebrafish Embryo Assay.

Micro-CT imaging of tumor angiogenesis: quantitative measures describing micromorphology and vascularization.

Recent advances in molecular, multimodal and theranostic ultrasound imaging.

Nanomedicines for inflammatory arthritis: head-to-head comparison of glucocorticoid-containing polymers, micelles, and liposomes.

Passive versus active tumor targeting using RGD- and NGR-modified polymeric nanomedicines.

PEG-pHPMAm-based polymeric micelles loaded with doxorubicin-prodrugs in combination antitumor therapy with oncolytic vaccinia viruses.

CCL2-dependent infiltrating macrophages promote angiogenesis in progressive liver fibrosis.

Iron Oxide-labeled Collagen Scaffolds for Non-invasive MR Imaging in Tissue Engineering.

Liposomal encapsulation of dexamethasone modulates cytotoxicity, inflammatory cytokine response, and migratory properties of primary human macrophages.

Characterizing EPR-mediated passive drug targeting using contrast-enhanced functional ultrasound imaging.

Absolute MR thermometry using nanocarriers.

The Theranostic Path to Personalized Nanomedicine.

Liposomal corticosteroids for the treatment of inflammatory disorders and cancer.

Absorption reconstruction improves biodistribution assessment of fluorescent nanoprobes using hybrid fluorescence-mediated tomography.

FMN-coated fluorescent USPIO for cell labeling and non-invasive MR imaging in tissue engineering.

Decationized polyplexes as stable and safe carrier systems for improved biodistribution in systemic gene therapy.

Nanoparticles for imaging: top or flop?

Decationized polyplexes for gene delivery.

Fluorescent cell-traceable dexamethasone-loaded liposomes for the treatment of inflammatory liver diseases.

USPIO-labeled textile materials for non-invasive MR imaging of tissue-engineered vascular grafts.

Liposomal delivery of dexamethasone attenuates prostate cancer bone metastatic tumor growth In Vivo.

Water-soluble dopamine-based polymers for photoacoustic imaging.

Theranostic USPIO-Loaded Microbubbles for Mediating and Monitoring Blood-Brain Barrier Permeation.

Enhanced in vitro and in vivo cellular imaging with green tea coated water-soluble iron oxide nanocrystals.

Fluorescently labeled microbubbles for facilitating translational molecular ultrasound studies.

Complete Regression of Xenograft Tumors upon Targeted Delivery of Paclitaxel via Π-Π Stacking Stabilized Polymeric Micelles.

Noninvasive Molecular Ultrasound Monitoring of Vessel Healing After Intravascular Surgical Procedures in a Preclinical Setup.

Flexible and modular MPI simulation framework and its use in modelling a μMPI.

A FIELD CANCELATION SIGNAL EXTRACTION METHOD FOR MAGNETIC PARTICLE IMAGING.

Core-Crosslinked Polymeric Micelles: Principles, Preparation, Biomedical Applications and Clinical Translation.

Fluorophore labeling of core-crosslinked polymeric micelles for multimodal in vivo and ex vivo optical imaging.

Applications of nanoparticles for diagnosis and therapy of cancer.