Margaret L. Gardel

CD98hc (SLC3A2) participates in fibronectin matrix assembly by mediating integrin signaling.

High resolution traction force microscopy based on experimental and computational advances.

Biophysics. Clutch dynamics.

Traction stress in focal adhesions correlates biphasically with actin retrograde flow speed.

Chapter 19: Mechanical response of cytoskeletal networks.

Mechanical integration of actin and adhesion dynamics in cell migration.

Mechanics of the F-actin cytoskeleton.

Identification and characterization of a small molecule inhibitor of formin-mediated actin assembly.

Optimization of traction force microscopy for micron-sized focal adhesions.

Transient frictional slip between integrin and the ECM in focal adhesions under myosin II tension.

Regulation of cell motile behavior by crosstalk between cadherin- and integrin-mediated adhesions.

Conserved F-actin dynamics and force transmission at cell adhesions.

A zyxin-mediated mechanism for actin stress fiber maintenance and repair.

Dynamic and structural signatures of lamellar actomyosin force generation.

Cell-ECM traction force modulates endogenous tension at cell-cell contacts.

Shear thickening of F-actin networks crosslinked with non-muscle myosin IIB.

Reconstitution of contractile actomyosin bundles.

Spatiotemporal constraints on the force-dependent growth of focal adhesions.

Tension is required but not sufficient for focal adhesion maturation without a stress fiber template.