Li Chen

Transcription factor Gbx2 acts cell-nonautonomously to regulate the formation of lineage-restriction boundaries of the thalamus.

The mouse homeobox gene Gbx2 is required for the development of cholinergic interneurons in the striatum.

Gbx2 regulates thalamocortical axon guidance by modifying the LIM and Robo codes.

Modulation of Host Osseointegration during Bone Regeneration by Controlling Exogenous Stem Cells Differentiation Using a Material Approach.

Computer-Automated Static, Dynamic and Cellular Bone Histomorphometry.

Histological Criteria that Distinguish Human and Mouse Bone Formed Within a Mouse Skeletal Repair Defect.

Ultraviolet B irradiation up-regulates MM1 and induces photoageing of the epidermis.

Biological effects of electron beam to target turning X-ray (EBTTX) on two freesia () cultivars.

Evaluation of fistula rates in three cleft palate techniques without relaxing incisions.

Efficacy-specific herbal group detection from traditional Chinese medicine prescriptions via hierarchical attentive neural network model.

MARCH5 restores endothelial cell function against ischaemic/hypoxia injury via Akt/eNOS pathway.

Rationale and design of the OPTIMAL-REPERFUSION trial: A prospective randomized multi-center clinical trial comparing different fibrinolysis-transfer percutaneous coronary intervention strategies in acute ST-segment elevation myocardial infarction.

COMMD1 upregulation is involved in copper efflux from ischemic hearts.

Layer-specific strain echocardiography may reflect regional myocardial impairment in patients with hypertrophic cardiomyopathy.

Effect of Sutellarin on Neurogenesis in Neonatal Hypoxia-Ischemia Rat Model: Potential Mechanisms of Action.

Effects of Abdominal Binders on Postoperative Pain and Functional Recovery: A Systematic Review and Meta-Analysis.

Regional anesthetics versus analgesia for stopping the persistent postsurgical pain: A meta-analysis.

Application of Nalbuphine in Trigeminal Ganglion Pulse Radiofrequency Surgery in Patients with Postherpetic Neuralgia.

Efficacy and Safety of Mulberry Twig Alkaloids Tablet for the Treatment of Type 2 Diabetes: A Multicenter, Randomized, Double-Blind, Double-Dummy, and Parallel Controlled Clinical Trial.

Cardiomyocyte-Specific COMMD1 Deletion Suppresses Ischemia-Induced Myocardial Apoptosis.

Activating transcription factor 4 regulates angiogenesis under lipid overload via methionine adenosyltransferase 2A-mediated endothelial epigenetic alteration.

Turn-on fluorescent probe for lipid droplet specific imaging of fatty liver and atherosclerosis.

The efficacy of ultrasound-guided stellate ganglion block in alleviating postoperative pain and ventricular arrhythmias and its application prospects.

A retrospective pilot study of preoperative mobilization program for older adults with hip fracture.

Recent progress in targeted delivery vectors based on biomimetic nanoparticles.

Selective suppression of M1 macrophages is involved in zinc inhibition of liver fibrosis in mice.

Self-assembled nano-Ag/Au@Au film composite SERS substrates show high uniformity and high enhancement factor for creatinine detection.

Sodium Lactate Accelerates M2 Macrophage Polarization and Improves Cardiac Function after Myocardial Infarction in Mice.

Reference values of respiratory impedance with impulse oscillometry in healthy Chinese adults.

A dual-channel language decoding from brain activity with progressive transfer training.

Panax notoginseng saponin attenuates the hypoxic-ischaemic injury in neonatal rats by regulating the expression of neurotrophin factors.

Automatic machine learning based on native T1 mapping can identify myocardial fibrosis in patients with hypertrophic cardiomyopathy.

A neural decoding algorithm that generates language from visual activity evoked by natural images.

Clinically Oriented Target Contour Evaluation Using Geometric and Dosimetric Indices Based on Simple Geometric Transformations.

A sandwich SERS detection system based on optical convergence and synergistic enhancement effects.

High-performance surface-enhanced Raman spectroscopy chip integrated with a micro-optical system for the rapid detection of creatinine in serum.

ERRATUM: Effect of Scutellarin on Neurogenesis in Neonatal Hypoxia-Ischemia Rat Model: Potential Mechanisms of Action.

Lymph-Node-Targeted Cholesterolized TLR7 Agonist Liposomes Provoke a Safe and Durable Antitumor Response.

Pulse oximetry waveform: A non-invasive physiological predictor for the return of spontaneous circulation in cardiac arrest patients ---- A multicenter, prospective observational study.

Scutellarin ameliorates neonatal hypoxic-ischemic encephalopathy associated with GAP43-dependent signaling pathway.

Rationale and design of a multi-center, prospective randomized controlled trial on the effects of sacubitril-valsartan versus enalapril on left ventricular remodeling in ST-elevation myocardial infarction: The PERI-STEMI study.

Effect of renal impairment on the pharmacokinetics and safety of dorzagliatin, a novel dual-acting glucokinase activator.

Multicycling of Epoxy Thermoset Through a Two-Step Strategy of Alcoholysis and Hydrolysis using a Self-Separating Catalysis System.

Cost-Effectiveness Analysis of Gefitinib Plus Chemotherapy versus Gefitinib Alone for Advanced Non-Small-Cell Lung Cancer with EGFR Mutations in China.

Neurological complications and infection mechanism of SARS-COV-2.

Short-read and long-read RNA sequencing of mouse hematopoietic stem cells at bulk and single-cell levels.

Causal Association of Coffee Consumption and Total, Knee, Hip and Self-Reported Osteoarthritis: A Mendelian Randomization Study.

Single-cell RNA sequencing reveals B cell-related molecular biomarkers for Alzheimer's disease.

Curcumin and Its Analogs as Potential Epigenetic Modulators: Prevention of Diabetes and Its Complications.

Inactivated SARS-CoV-2 induces acute respiratory distress syndrome in human ACE2-transgenic mice.

ERRATUM: Effect of Scutellarin on Neurogenesis in Neonatal Hypoxia-Ischemia Rat Model: Potential Mechanisms of Action.

A CNN-transformer hybrid approach for decoding visual neural activity into text.

Synthesis of Silacyclohexanones from Divinylsilanes and Allylamines by a Rh-Catalyzed Cyclization.

Integrated single-cell RNA sequencing analysis reveals distinct cellular and transcriptional modules associated with survival in lung cancer.

Application of Decision Tree Intelligent Algorithm in Data Analysis of Physical Health Test.

Effect of a preoperative mobilization program on perioperative complications and function recovery in older adults with femoral neck fracture.

Electrochemical Ring-Opening Dicarboxylation of Strained Carbon-Carbon Single Bonds with CO: Facile Synthesis of Diacids and Derivatization into Polyesters.

Intranasal COVID-19 vaccines: From bench to bed.

Recyclable, malleable and intrinsically flame-retardant epoxy resin with catalytic transesterification.

The prospective multiple-centre randomized controlled clinical study of high-dose amoxicillin-proton pump inhibitor dual therapy for infection in Sichuan areas.

Regulatory Mechanism of MicroRNA-9 / Long Non-Coding RNA XIST Expression on Mouse Macrophage RAW264.7 Apoptosis Induced by Oxidized Low Density Lipoprotein.

Eye disorders associated with newer antiepileptic drugs: A real-world disproportionality analysis of FDA adverse event reporting system.

Histones released by NETosis enhance the infectivity of SARS-CoV-2 by bridging the spike protein subunit 2 and sialic acid on host cells.

Glucocorticoids rapidly promote YAP phosphorylation via the cAMP-PKA pathway to repress mouse cardiomyocyte proliferative potential.

Diagnostic accuracy of CT-derived and angiogram-derived fractional flow reserve.

SARS-CoV-2 Omicron variant: Immune escape and vaccine development.

Drug resistance prediction and resistance genes identification in Mycobacterium tuberculosis based on a hierarchical attentive neural network utilizing genome-wide variants.

Anaplastic Lymphoma Kinase Tyrosine Kinase Inhibitor-Associated Cardiotoxicity: A Recent Five-Year Pharmacovigilance Study.

Co-Delivery of Dexamethasone and Captopril by α8 Integrin Antibodies Modified Liposome-PLGA Nanoparticle Hybrids for Targeted Anti-Inflammatory/Anti-Fibrosis Therapy of Glomerulonephritis.

Causal Association Between Tea Consumption and Kidney Function: A Mendelian Randomization Study.

Diagnostic performance of coronary computed tomography angiography-derived fractional flow reverse in lesion-specific ischemia patients with different Gensini score levels.

Dorzagliatin add-on therapy to metformin in patients with type 2 diabetes: a randomized, double-blind, placebo-controlled phase 3 trial.

Dorzagliatin in drug-naïve patients with type 2 diabetes: a randomized, double-blind, placebo-controlled phase 3 trial.

Generation of a live attenuated influenza A vaccine by proteolysis targeting.

The prognostic value of machine learning techniques versus cox regression model for head and neck cancer.

Retrieving entrapped guidewire using rotablation technique: case series and literature review.

Nanomaterial-Based Drug Delivery System Targeting Lymph Nodes.

Evidence-based nursing in the operating room of obstetrics and gynecology departments alleviates patients' adverse moods and improves their quality of life.

The age-specific pathological changes of β-amyloid plaques in the cortex and hippocampus of APP/PS1 transgenic AD mice.

P75 neurotrophin receptor as a therapeutic target for drug development to treat neurological diseases.

The vertebrate- and testis- specific transmembrane protein C11ORF94 plays a critical role in sperm-oocyte membrane binding.

A self-assembled trimeric protein vaccine induces protective immunity against Omicron variant.

Fluoroquinolone-associated suspected tendonitis and tendon rupture: A pharmacovigilance analysis from 2016 to 2021 based on the FAERS database.

Short dual antiplatelet therapy in patients with high bleeding risk undergoing percutaneous coronary intervention: a systematic review and meta-analysis.

Core-Shell Structured Porous Calcium Phosphate Bioceramic Spheres for Enhanced Bone Regeneration.

The increased inter-brain neural synchronization in prefrontal cortex between simulated patient and acupuncturist during acupuncture stimulation: Evidence from functional near-infrared spectroscopy hyperscanning.

Clinical application of oscillometry in respiratory diseases: an impulse oscillometry registry.

Adaptable Phosphate Networks towards Robust, Reprocessable, Weldable, and Alertable-Yet-Extinguishable Epoxy Vitrimer.

PPTPS: Building privacy-preserving auditable service with traceable timeliness for public cloud storage.

SARS-CoV-2 variants, immune escape, COVID-19 vaccine, and therapeutic strategies.

A flexible surface-enhanced Raman Spectroscopy chip integrated with microlens.

JMJD3 Is Required for Acute Pancreatitis and Pancreatitis-Associated Lung Injury.

CD44 promotes angiogenesis in myocardial infarction through regulating plasma exosome uptake and further enhancing FGFR2 signaling transduction.

Hypoxia-mimicking scaffolds with controlled release of DMOG and PTHrP to promote cartilage regeneration via the HIF-1α/YAP signaling pathway.

Post-marketing safety of immunomodulatory drugs in multiple myeloma: A pharmacovigilance investigation based on the FDA adverse event reporting system.

Implications of sleep disorders for periodontitis.

Cellular features of localized microenvironments in human meniscal degeneration: a single-cell transcriptomic study.

Tripterin liposome relieves severe acute respiratory syndrome as a potent COVID-19 treatment.

Association between different GLP-1 receptor agonists and gastrointestinal adverse reactions: A real-world disproportionality study based on FDA adverse event reporting system database.

DLP fabrication of customized porous bioceramics with osteoinduction ability for remote isolation bone regeneration.

SCGN deficiency is a risk factor for autism spectrum disorder.

CARK3-mediated ADF4 regulates hypocotyl elongation and soil drought stress in Arabidopsis.

Predictive value of magnetic resonance imaging radiomics-based machine learning for disease progression in patients with high-grade glioma.

Micro-CT analysis of osteomyelitis of rabbit tibial for model establishment and biomaterials application in tissue engineering.

The role of mitochondria in the peri-implant microenvironment.

Optimized Design and Preparation of Ag Nanoparticle Multilayer SERS Substrates with Excellent Sensing Performance.

GelMA/κ-carrageenan double-network hydrogels with superior mechanics and biocompatibility.

Platinum drugs-related safety profile: The latest five-year analysis from FDA adverse event reporting system data.

Extracellular acidosis restricts one-carbon metabolism and preserves T cell stemness.

Cost-effectiveness of sintilimab plus chemotherapy versus chemotherapy alone as first-line treatment of locally advanced or metastatic oesophageal squamous cell carcinoma.

Proliferative exhausted CD8 T cells exacerbate long-lasting anti-tumor effects in human papillomavirus-positive head and neck squamous cell carcinoma.

Urine-derived mesenchymal stem cells-derived exosomes enhances survival and proliferation of aging retinal ganglion cells.

Trimeric protein vaccine based on Beta variant elicits robust immune response against BA.4/5-included SARS-CoV-2 Omicron variants.

Severe hematuria in a patient receiving bevacizumab and pembrolizumab for metastatic cervical cancer: a case report.

Methodological issues of the central mechanism of two classic acupuncture manipulations based on fNIRS: suggestions for a pilot study.

Heterologous vaccination with subunit protein vaccine induces a superior neutralizing capacity against BA.4/5-included SARS-CoV-2 variants than homologous vaccination of mRNA vaccine.

Characteristics and Trends in Clinical Trials of Cardiovascular Drugs in China from 2009 to 2021.

Neurotoxicity induced by taxane-derived drugs: analysis of the FAERS database 2017-2021.

The changing landscape of drug clinical trials on cardiometabolic diseases in China, 2009-2021.

Knockout of cyclase-associated protein CAP1 confers tolerance towards salt and osmotic stress in Arabidopsis.

Cationic crosslinked carbon dots-adjuvanted intranasal vaccine induces protective immunity against Omicron-included SARS-CoV-2 variants.

The fate and prospects of stem cell therapy in the treatment of hypoxic-ischemic encephalopathy.

The regulations on cortical activation and functional connectivity of the dorsolateral prefrontal cortex-primary somatosensory cortex elicited by acupuncture with reinforcing-reducing manipulation.

Pulsed Electromagnetic Fields Combined With Adipose-Derived Stem Cells Protect Ischemic Myocardium by Regulating miR-20a-5p/E2F1/p73 Signaling.

Cryo-EM structure of the Mon1-Ccz1-RMC1 complex reveals molecular basis of metazoan RAB7A activation.

Role of miR-182 in cardiovascular and cerebrovascular diseases.

Transcranial Doppler Ultrasonography detection on cerebrovascular flow for evaluating neonatal hypoxic-ischemic encephalopathy modeling.

Granzyme B + CD8 + T cells with terminal differentiated effector signature determine multiple sclerosis progression.

Identification of necroptosis-related long non-coding RNAs prognostic signature and the crucial lncRNA in bladder cancer.

6-month consequences of COVID-19 in patients discharged from hospital: a cohort study.

Current analysis of hypoxic-ischemic encephalopathy research issues and future treatment modalities.

Implications of MCU complex in metabolic diseases.

Aesthetic evaluation of nasolabial reconstruction using abbe flap in bilateral cleft lip patients with secondary deformities.

Medication overdose data analysis: a review of medication error reports in the FDA adverse event reporting system (FAERS).

Changes in Drug Clinical Trials of Thyroid Diseases in China, 2009-2022.

Advances in the study of acetaminophen-induced liver injury.

Comparison of Different Chronic Maintenance Antithrombotic Strategies in Patients with Coronary Artery Disease: A Systematic Review and Network Meta-Analysis.

Safety profiles of methylphenidate, amphetamine, and atomoxetine: analysis of spontaneous reports submitted to the food and drug administration adverse event reporting system.

Transcranial Doppler Ultrasonography detection on cerebral infarction and blood vessels to evaluate hypoxic ischemic encephalopathy modeling.

Neighboring Molecular Engineering in Diels-Alder Chemistry Enabling Easily Recyclable Carbon Fiber Reinforced Composites.

A case of early-onset periodontitis with vitamin D deficiency: A case report and literature review.

AQP4 knockout promotes neurite outgrowth via upregulating GAP43 expression in infant rats with hypoxic-ischemic brain injury.

Routes and methods of neural stem cells injection in cerebral ischemia.

Corrigendum: Advances in the study of acetaminophen-induced liver injury.

PRMD: an integrated database for plant RNA modifications.

Dry eye disease among patients infected with the SARS-CoV-2 Omicron variant: a cross-sectional study.

MAGI2 ameliorates podocyte apoptosis of diabetic kidney disease through communication with TGF-β-Smad3/nephrin pathway.

Bivalirudin versus heparin in contemporary percutaneous coronary interventions for patients with acute coronary syndrome: a systematic review and meta-analysis.

The Association of Hypertension with Perfluoroalkyl and Polyfluoroalkyl Substances.

Multilayer analysis of dynamic network reconfiguration in pediatric posttraumatic stress disorder.

Safe utilization evaluation of two typical traditional Chinese medicinal materials in Cd-contaminated soil based on the analysis of Cd transfer and AHP model.

Comprehensive Insights that Targeting PIM for Cancer Therapy: Prospects and Obstacles.

Vof16-miR-185-5p-GAP43 network improves the outcomes following spinal cord injury via enhancing self-repair and promoting axonal growth.

Microarray analysis of lncRNAs and mRNAs in spinal cord contusion rats with iPSC-derived A2B5 oligodendrocyte precursor cells transplantation.

Diagnostic performance of angiography-derived fractional flow reserve and CT-derived fractional flow reserve: A systematic review and Bayesian network meta-analysis.

Unlocking hormesis and toxic effects induced by cadmium in Polygonatum cyrtonema Hua based on morphology, physiology and metabolomics.

Novel Digital SERS-Microfluidic Chip for Rapid and Accurate Quantification of Microorganisms.

Dynamic Shape Change of Liquid Crystal Polymer Based on An Order-Order Phase Transition.

Transplantation of human placental chorionic plate-derived mesenchymal stem cells for repair of neurological damage in neonatal hypoxic-ischemic encephalopathy.

Tetrahedral DNA loaded siCCR2 restrains M1 macrophage polarization to ameliorate pulmonary fibrosis in chemoradiation-induced murine model.

Validation of phenomenon and cross-sectional investigation of predictors for a post-COVID-19 surge of osteoporosis outpatients in China.

Targeting Senescent Alveolar Epithelial Cells Using Engineered Mesenchymal Stem Cell-Derived Extracellular Vesicles To Treat Pulmonary Fibrosis.

Predictive potentials of glycosylation-related genes in glioma prognosis and their correlation with immune infiltration.

To explore the potential mechanisms of cognitive impairment in children with MRI-negative pharmacoresistant epilepsy due to focal cortical dysplasia: A pilot study from gray matter structure view.

Association of Interleukin-17 Inhibitors With Hypertension in Patients With Autoimmune Diseases: A Systematic Review and Meta-analysis on Randomized Controlled Trials.

Percutaneous sealing of a left ventricular pseudoaneurysm evolving from intramyocardial dissecting haematoma.

Data mining and safety analysis of traditional immunosuppressive drugs: a pharmacovigilance investigation based on the FAERS database.

Nesprin-2 is a novel scaffold protein for telethonin and FHL-2 in the cardiomyocyte sarcomere.

Right Coronary Artery Occlusion Due to Foreign Body From Left Chest Traumatic Injury.

Cytosolic ABA Receptor Kinases phosphorylate the D6 PROTEIN KINASE leading to its stabilization which promotes Arabidopsis growth.

The diversity of inhibitory receptor co-expression patterns of exhausted CD8 T cells in oropharyngeal carcinoma.

A chimeric adenovirus-vectored vaccine based on Beta spike and Delta RBD confers a broad-spectrum neutralization against Omicron-included SARS-CoV-2 variants.

Comparison of safety of acetaminophen and ibuprofen in minors: based on the FAERS database.

Endocrine system-related adverse events associated with PD-1/PD-L1 inhibitors: data mining from the FDA adverse event reporting system.

Recent discovery and development of AXL inhibitors as antitumor agents.

Advances in neuronal reprogramming for neurodegenerative diseases: Strategies, controversies, and opportunities.

Awareness and associated factors of venous thromboembolism in breast cancer surgical patients: a cross-sectional study.

The association between halitosis and periodontitis: a systematic review and meta-analysis.

The role of periodontitis in the development of atherosclerotic cardiovascular disease in participants with the components of metabolic syndrome: a systematic review and meta-analysis.

Post-marketing risk analysis of bendamustine: a real-world approach based on the FAERS database.

Anxiety mediates association between sex and jaw function limitation in temporomandibular disorder patients from China.

Ultrahigh Heat/Fire-Resistant, Mechanically Robust, and Closed-Loop Chemical Recyclable Polycarbonate Enabled by Facile Bond Dissociation Energy Modulation.

Hydrogen Sulfide Promotes Postnatal Cardiomyocyte Proliferation by Upregulating SIRT1 Signaling Pathway.

A multicentre, randomised, double-blind, double-dummy, parallel-controlled, phase 3 clinical trial assessing the efficacy and safety of intravenous nemonoxacin malate vs. levofloxacin for community-acquired pneumonia in adult patients.

Development and therapeutic perspectives of CXCR4 antagonists for disease therapy.

Wnt/β-catenin signaling pathway in carcinogenesis and cancer therapy.

Comparison of Infection Risks Between Various Inhaled and Intranasal Corticosteroids: A Pharmacovigilance Analysis Based on the FAERS Database.

Towards Sustainable and Fire-Safe Thermosets Using Phosphorus-Containing Covalent Adaptable Networks.

Cardiorespiratory motion characteristics and their dosimetric impact on cardiac stereotactic body radiotherapy.

Anterior Cervical Discectomy and Fusion with Zero-Profile Anchored Spacer Versus Plate and Cage for 3-Level Contiguous Cervical Degenerative Disease: A Systematic Review and Meta-Analysis.

Quantifying dose uncertainties resulting from cardiorespiratory motion in intensity-modulated proton therapy for cardiac stereotactic body radiotherapy.

Association of complete blood count parameters with the risk of incident pulmonary heart disease in pneumoconiosis: a retrospective cohort study.

Relationship between cognitive function and sleep quality in middle-aged and older adults for minimizing disparities and achieving equity in health: Evidence from multiple nationwide cohorts.

Association between depressive duration and cognitive decline in middle-aged and older adults: Evidence from the Health and Retirement Study 2010-2018.

Characteristics of eye disorders induced by atypical antipsychotics: a real-world study from 2016 to 2022 based on Food and Drug Administration Adverse Event Reporting System.

Coronary Artery Embolism Secondary to Q Fever Endocarditis.

Safety analysis of quinolones use in minors-based on the FAERS database.

Safety analysis of fluoroquinolone drugs in elderly patients over 65 based on FAERS.

p75ECD-Fc reverses neonatal hypoxic-ischemic encephalopathy-induced neurological deficits and inhibits apoptosis associated with Nestin.

SARS-CoV-2 Delta and Omicron variants resist spike cleavage by human airway trypsin-like protease.

Comparison of the effects of contrast medium and low-molecular-weight dextran on coronary optical coherence tomographic imaging in relatively complex coronary lesions.

Single-cell RNA sequencing reveals peripheral immunological features in Parkinson's Disease.