UCIBIO,
Life Sciences Department,
Faculty of Sciences and Technology,
CEDOC,
NOVA Medical School,
UCIBIO, Life Sciences Department, Faculty of Sciences and Technology,
CEDOC, NOVA Medical School,
Associate Laboratory i4HB - Institute for Health and Bioeconomy,
NOVA School of Science and Technology,
UCIBIO - Applied Molecular Biosciences Unit,
Department of Life Sciences,
CDG & Allies - Professionals and Patient Associations International Network (CDG & Allies - PPAIN),
Associate Laboratory i4HB - Institute for Health and Bioeconomy, NOVA School of Science and Technology,
UCIBIO - Applied Molecular Biosciences Unit, Department of Life Sciences, NOVA School of Science and Technology,
CDG & Allies - Professionals and Patient Associations International Network (CDG & Allies - PPAIN), Department of Life Sciences, NOVA School of Science and Technology
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Identification and physical organization of the gene cluster involved in the biosynthesis of Burkholderia cepacia complex exopolysaccharide.
Biochemical and biophysical research communications Dec, 2003 | Pubmed ID: 14637140
Studies on the involvement of the exopolysaccharide produced by cystic fibrosis-associated isolates of the Burkholderia cepacia complex in biofilm formation and in persistence of respiratory infections.
Journal of clinical microbiology Jul, 2004 | Pubmed ID: 15243059
Functional and topological analysis of the Burkholderia cenocepacia priming glucosyltransferase BceB, involved in the biosynthesis of the cepacian exopolysaccharide.
Journal of bacteriology Jul, 2005 | Pubmed ID: 15995219
Surface alpha 2-3- and alpha 2-6-sialylation of human monocytes and derived dendritic cells and its influence on endocytosis.
Glycoconjugate journal Apr, 2008 | Pubmed ID: 18080182
Efficacy of bacille Calmette-Guérin immunotherapy predicted by expression of antigen-presenting molecules and chemokines.
Urology Oct, 2009 | Pubmed ID: 19428084
Effect of sialic acid loss on dendritic cell maturation.
Immunology Sep, 2009 | Pubmed ID: 19740323
ST3Gal.I sialyltransferase relevance in bladder cancer tissues and cell lines.
BMC cancer Oct, 2009 | Pubmed ID: 19811634
Human dendritic cells contain cell surface sialyltransferase activity.
Immunology letters Jun, 2010 | Pubmed ID: 20206207
Effects of bevacizumab on autocrine VEGF stimulation in bladder cancer cell lines.
Urologia internationalis , 2011 | Pubmed ID: 21212629
Sialyl Lewisx-dependent binding of human monocyte-derived dendritic cells to selectins.
Biochemical and biophysical research communications Jun, 2011 | Pubmed ID: 21596017
Screening of congenital cytomegalovirus infection by real-time PCR in urine pools.
European journal of pediatrics Jan, 2012 | Pubmed ID: 21614511
The role of sugars in dendritic cell trafficking.
Annals of biomedical engineering Apr, 2012 | Pubmed ID: 22045510
IL-4 and TNF-α polymorphisms are associated with risk of multiple superficial tumors or carcinoma in situ development.
Urologia internationalis , 2011 | Pubmed ID: 22104567
The phagocytic capacity and immunological potency of human dendritic cells is improved by α2,6-sialic acid deficiency.
Immunology Mar, 2013 | Pubmed ID: 23113614
Diagnostic value of endobronchial and endoscopic ultrasound-guided fine needle aspiration for accessible lung cancer lesions after non-diagnostic conventional techniques: a prospective study.
BMC cancer Mar, 2013 | Pubmed ID: 23510132
Overexpression of tumour-associated carbohydrate antigen sialyl-Tn in advanced bladder tumours.
Molecular oncology Jun, 2013 | Pubmed ID: 23567325
Biological characterization of the antiproliferative potential of Co(II) and Sn(IV) coordination compounds in human cancer cell lines: a comparative proteomic approach.
Drug metabolism and drug interactions , 2013 | Pubmed ID: 23800656
Intravital microscopy technique to study parasite dynamics in the labyrinth layer of the mouse placenta.
Parasitology international Feb, 2014 | Pubmed ID: 23845789
Cytokeratin 19, carcinoembryonic antigen, and epithelial cell adhesion molecule detect lung cancer lymph node metastasis in endobronchial ultrasound-guided transbronchial aspiration samples.
Clinical lung cancer Nov, 2013 | Pubmed ID: 23886796
FASL polymorphism is associated with response to bacillus Calmette-Guérin immunotherapy in bladder cancer.
Urologic oncology Jan, 2014 | Pubmed ID: 23948181
Synthesis and evaluation of N-acylamino acids derivatives of triazenes. Activation by tyrosinase in human melanoma cell lines.
European journal of medicinal chemistry , 2013 | Pubmed ID: 24125877
Dendritic cells: a spot on sialic Acid.
Frontiers in immunology Dec, 2013 | Pubmed ID: 24409183
Sialyl Tn-expressing bladder cancer cells induce a tolerogenic phenotype in innate and adaptive immune cells.
Molecular oncology May, 2014 | Pubmed ID: 24656965
Sialyl-tn in cancer: (how) did we miss the target?
Biomolecules Oct, 2012 | Pubmed ID: 24970145
Meeting report on EMBO workshop: glycobiology and glycochemistry, applications to human health and disease.
Glycobiology Sep, 2014 | Pubmed ID: 25028393
Protein disulfide isomerases: Impact of thapsigargin treatment on their expression in melanoma cell lines.
International journal of biological macromolecules Aug, 2015 | Pubmed ID: 25912252
Characterization of antiproliferative potential and biological targets of a copper compound containing 4'-phenyl terpyridine.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry Sep, 2015 | Pubmed ID: 26077814
Immature myeloid cells and tolerogenic cytokine profile in lung adenocarcinoma metastatic lymph nodes assessed by endobronchial ultrasound.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine Jan, 2016 | Pubmed ID: 26264617
Challenges in Antibody Development against Tn and Sialyl-Tn Antigens.
Biomolecules Aug, 2015 | Pubmed ID: 26270678
Sialic acid removal from dendritic cells improves antigen cross-presentation and boosts anti-tumor immune responses.
Oncotarget Jul, 2016 | Pubmed ID: 27203391
Immunological aspects of congenital disorders of glycosylation (CDG): a review.
Journal of inherited metabolic disease Nov, 2016 | Pubmed ID: 27393411
Using dendritic cells to evaluate how Burkholderia cenocepacia clonal isolates from a chronically infected cystic fibrosis patient subvert immune functions.
Medical microbiology and immunology Dec, 2016 | Pubmed ID: 27987042
Expression of sialyl-Tn sugar antigen in bladder cancer cells affects response to (BCG) and to oxidative damage.
Oncotarget Aug, 2017 | Pubmed ID: 28903359
Blood Supply to the Integument of the Abdomen of the Rat: A Surgical Perspective.
Plastic and reconstructive surgery. Global open Sep, 2017 | Pubmed ID: 29062636
Reconstruction of a long defect of the ulnar artery and nerve with an arterialized neurovenous free flap in a teenager: A case report and literature review.
Microsurgery Feb, 2018 | Pubmed ID: 29094390
Halilectin-3, a Lectin from the Marine Sponge Haliclona caerulea, Induces Apoptosis and Autophagy in Human Breast Cancer MCF7 Cells Through Caspase-9 Pathway and LC3-II Protein Expression.
Anti-cancer agents in medicinal chemistry , 2018 | Pubmed ID: 29141557
Inhibition of fucosylation in human invasive ductal carcinoma reduces E-selectin ligand expression, cell proliferation, and ERK1/2 and p38 MAPK activation.
Molecular oncology 05, 2018 | Pubmed ID: 29215790
Antitumor Efficacy of Human Monocyte-Derived Dendritic Cells: Comparing Effects of two Monocyte Isolation Methods.
Biological procedures online , 2018 | Pubmed ID: 29434528
Oxidative damage and response to Bacillus Calmette-Guérin in bladder cancer cells expressing sialyltransferase ST3GAL1.
BMC cancer 02, 2018 | Pubmed ID: 29454317
Staining of E-selectin ligands on paraffin-embedded sections of tumor tissue.
BMC cancer 05, 2018 | Pubmed ID: 29716546
Ligation of the CD44 Glycoform HCELL on Culture-Expanded Human Monocyte-Derived Dendritic Cells Programs Transendothelial Migration.
Journal of immunology (Baltimore, Md. : 1950) 08, 2018 | Pubmed ID: 29941663
BD-2 and BD-3 increase skin flap survival in a model of ischemia and Pseudomonas aeruginosa infection.
Scientific reports 05, 2019 | Pubmed ID: 31133641
Carcinoembryonic antigen is a sialyl Lewis x/a carrier and an E‑selectin ligand in non‑small cell lung cancer.
International journal of oncology Nov, 2019 | Pubmed ID: 31793656
MHC Class I Stability is Modulated by Cell Surface Sialylation in Human Dendritic Cells.
Pharmaceutics Mar, 2020 | Pubmed ID: 32164343
[Asthma genetic factors].
Revista portuguesa de pneumologia , 2006 | Pubmed ID: 17301923
Cell-Specific Variation in E-Selectin Ligand Expression among Human Peripheral Blood Mononuclear Cells: Implications for Immunosurveillance and Pathobiology.
Journal of immunology (Baltimore, Md. : 1950) May, 2017 | Pubmed ID: 28330896
Gla-rich protein function as an anti-inflammatory agent in monocytes/macrophages: Implications for calcification-related chronic inflammatory diseases.
PloS one , 2017 | Pubmed ID: 28542410
Optimization of an Arterialized Venous Fasciocutaneous Flap in the Abdomen of the Rat.
Plastic and reconstructive surgery. Global open Aug, 2017 | Pubmed ID: 28894657
Public and patient involvement in needs assessment and social innovation: a people-centred approach to care and research for congenital disorders of glycosylation.
BMC health services research Sep, 2017 | Pubmed ID: 28950866
Structural characterization of two isolectins from the marine red alga Solieria filiformis (Kützing) P.W. Gabrielson and their anticancer effect on MCF-7 breast cancer cells.
International journal of biological macromolecules Feb, 2018 | Pubmed ID: 28970169
Antibacterial activity of a new lectin isolated from the marine sponge Chondrilla caribensis.
International journal of biological macromolecules Apr, 2018 | Pubmed ID: 29175164
E-Selectin Ligands in the Human Mononuclear Phagocyte System: Implications for Infection, Inflammation, and Immunotherapy.
Frontiers in immunology , 2017 | Pubmed ID: 29403469
Reconstruction of a 10-mm-long median nerve gap in an ischemic environment using autologous conduits with different patterns of blood supply: A comparative study in the rat.
PloS one , 2018 | Pubmed ID: 29659600
CDG Therapies: From Bench to Bedside.
International journal of molecular sciences Apr, 2018 | Pubmed ID: 29702557
A functional glycoproteomics approach identifies CD13 as a novel E-selectin ligand in breast cancer.
Biochimica et biophysica acta. General subjects Sep, 2018 | Pubmed ID: 29777742
Linking Glycation and Glycosylation With Inflammation and Mitochondrial Dysfunction in Parkinson's Disease.
Frontiers in neuroscience , 2018 | Pubmed ID: 29930494
Novel monoclonal antibody L2A5 specifically targeting sialyl-Tn and short glycans terminated by alpha-2-6 sialic acids.
Scientific reports Aug, 2018 | Pubmed ID: 30111774
Exploring sialyl-Tn expression in microfluidic-isolated circulating tumour cells: A novel biomarker and an analytical tool for precision oncology applications.
New biotechnology Mar, 2019 | Pubmed ID: 30273682
Patient and observer reported outcome measures to evaluate health-related quality of life in inherited metabolic diseases: a scoping review.
Orphanet journal of rare diseases Nov, 2018 | Pubmed ID: 30486833
CDG and immune response: From bedside to bench and back.
Journal of inherited metabolic disease Jan, 2020 | Pubmed ID: 31095764
Artificial Intelligence (AI) in Rare Diseases: Is the Future Brighter?
Genes Nov, 2019 | Pubmed ID: 31783696
Extended half-life target module for sustainable UniCAR T-cell treatment of STn-expressing cancers.
Journal of experimental & clinical cancer research : CR May, 2020 | Pubmed ID: 32370811
New Insights into Immunological Involvement in Congenital Disorders of Glycosylation (CDG) from a People-Centric Approach.
Journal of clinical medicine Jul, 2020 | Pubmed ID: 32635232
L1CAM as an E-selectin Ligand in Colon Cancer.
International journal of molecular sciences Nov, 2020 | Pubmed ID: 33167483
Assessment of the Safety and Therapeutic Benefits of Convalescent Plasma in COVID-19 Treatment: A Systematic Review and Meta-Analysis.
Frontiers in medicine , 2021 | Pubmed ID: 33889590
Artificial Intelligence in Epigenetic Studies: Shedding Light on Rare Diseases.
Frontiers in molecular biosciences , 2021 | Pubmed ID: 34026829
Development of Dl1.72, a Novel Anti-DLL1 Antibody with Anti-Tumor Efficacy against Estrogen Receptor-Positive Breast Cancer.
Cancers Aug, 2021 | Pubmed ID: 34439228
A computer-aided drug design approach to discover tumour suppressor p53 protein activators for colorectal cancer therapy.
Bioorganic & medicinal chemistry Jan, 2022 | Pubmed ID: 34861473
Editorial: Biomarkers in Genitourinary Cancers, Volume I.
Frontiers in oncology , 2022 | Pubmed ID: 35880166
Concerted Regulation of Glycosylation Factors Sustains Tissue Identity and Function.
Biomedicines Jul, 2022 | Pubmed ID: 36009354
Sialyl Lewis and Cytokeratin Crosstalk in Triple Negative Breast Cancer.
Cancers Jan, 2023 | Pubmed ID: 36765690
Computational Approaches Drive Developments in Immune-Oncology Therapies for PD-1/PD-L1 Immune Checkpoint Inhibitors.
International journal of molecular sciences Mar, 2023 | Pubmed ID: 36982981
Congenital disorders of glycosylation (CDG): state of the art in 2022.
Orphanet journal of rare diseases Oct, 2023 | Pubmed ID: 37858231
Diogo Casal1,4,
Diogo Pais1,
Inês Iria3,4,
Eduarda Mota-Silva5,
Maria-Angélica Almeida2,
Sara Alves6,
Cláudia Pen6,
Ana Farinho4,
Luís Mascarenhas-Lemos1,6,
José Ferreira-Silva6,
Mário Ferraz-Oliveira6,
Valentina Vassilenko5,
Paula A. Videira3,4,
João Gory O'Neill1,5
1Anatomy Department, NOVA Medical School, Universidade NOVA de Lisboa,
2Plastic and Reconstructive Surgery Department and Burn Unit, Centro Hospitalar de Lisboa Central - Hospital de São José,
3UCIBIO, Life Sciences Department, Faculty of Sciences and Technology, Universidade NOVA de Lisboa,
4CEDOC, NOVA Medical School, Universidade NOVA de Lisboa,
5Physics Department, Faculty of Sciences and Technology, LIBPhys,
6Pathology Department, Centro Hospitalar de Lisboa Central – Hospital de São José
Diogo Casal*,1,2,
Eduarda Mota-Silva*,3,
Inês Iria4,5,
Diogo Pais1,
Ana Farinho6,
Sara Alves7,
Cláudia Pen7,
Luís Mascarenhas-Lemos7,
José Ferreira-Silva7,
Mário Ferraz-Oliveira7,
Valentina Vassilenko3,
Paula A. Videira4,5,
João Goyri-O'Neill1
1Anatomy Department, NOVA Medical School,
2Plastic and Reconstructive Surgery Department and Burn Unit, Centro Hospitalar de Lisboa Central,
3Physics Department, Faculty of Sciences and Technology, LIBPhys,
4Glycoimmunology, CEDOC, NOVA Medical School,
5UCIBIO, Life Sciences Department, Faculty of Sciences and Technology, Universidade NOVA de Lisboa,
6Tissue Repair Unit, CEDOC, NOVA Medical School,
7Pathology Department, Centro Hospitalar de Lisboa Central
Vanessa C. C. Luz1,2,
Zélia Silva1,2,
Patrícia Sobral1,2,3,
Ankit Tanwar4,5,
Rachel L. Paterson6,
Paula A. Videira1,2,7
1Associate Laboratory i4HB - Institute for Health and Bioeconomy, NOVA School of Science and Technology, Universidade NOVA de Lisboa,
2UCIBIO - Applied Molecular Biosciences Unit, Department of Life Sciences, NOVA School of Science and Technology, Universidade NOVA de Lisboa,
3LAQV and REQUIMTE, Departamento de Química, Faculdade de Ciências e Tecnologia, Universidade NOVA de Lisboa,
4Department of Microbiology and Immunology, Albert Einstein College of Medicine,
5Department of Oncology, Albert Einstein College of Medicine,
6Stemmatters, Biotecnologia e Medicina Regenerativa SA, Parque de Ciência e Tecnologia Avepark, Zona Industrial da Gandra,
7CDG & Allies - Professionals and Patient Associations International Network (CDG & Allies - PPAIN), Department of Life Sciences, NOVA School of Science and Technology, Universidade NOVA de Lisboa