Arnold Caplan

The STRO-1+ marrow cell population is multipotential.

Treatment of osteochondral defects with autologous bone marrow in a hyaluronan-based delivery vehicle.

In vivo remodeling.

In vivo remodeling: breakout session summary.

Immunochemical and mechanical characterization of cartilage subtypes in rabbit.

Bioreactors mediate the effectiveness of tissue engineering scaffolds.

Repair of osteochondral defect with tissue-engineered two-phase composite material of injectable calcium phosphate and hyaluronan sponge.

Age-related changes in the proteoglycans of human skin. Specific cleavage of decorin to yield a major catabolic fragment in adult skin.

Embryonic development and the principles of tissue engineering.

Production of a monoclonal antibody, DF-5, that identifies cells at the epithelial-mesenchymal interface in normal human skin. APN/CD13 is an epithelial-mesenchymal marker in skin.

Cytokines and glucocorticoids differentially regulate APN/CD13 and DPPIV/CD26 enzyme activities in cultured human dermal fibroblasts.

Fibroblast heterogeneity: more than skin deep.

Cellular interactions and bone healing responses to a novel porous tricalcium phosphate bone graft material.

Targeted delivery of progenitor cells for cartilage repair.

A new human somatic stem cell from placental cord blood with intrinsic pluripotent differentiation potential.

Generation of pluripotent stem cells and their differentiation to the chondrocytic phenotype.

Adult stem cell driven genesis of human-shaped articular condyle.

Sustained Wnt protein expression in chondral constructs from mesenchymal stem cells.

Osteochondral defect repair by demineralized cortical bone matrix.

FGF-2 enhances the mitotic and chondrogenic potentials of human adult bone marrow-derived mesenchymal stem cells.

Controlled release of hyaluronan oligomers from biodegradable polymeric microparticle carriers.

Tissue engineering of autologous cartilage grafts in three-dimensional in vitro macroaggregate culture system.

Repair of osteochondral defects with hyaluronan- and polyester-based scaffolds.

Effect of transforming growth factor beta 2 on marrow-infused foam poly(propylene fumarate) tissue-engineered constructs for the repair of critical-size cranial defects in rabbits.

Review: mesenchymal stem cells: cell-based reconstructive therapy in orthopedics.

A simple method for stem cell labeling with fluorine 18.

Hyaluronan-based polymer scaffold modulates the expression of inflammatory and degradative factors in mesenchymal stem cells: Involvement of Cd44 and Cd54.

Mesenchymal stem cells as trophic mediators.

A rapid seeding technique for the assembly of large cell/scaffold composite constructs.

Toxic effects of gentamicin on marrow-derived human mesenchymal stem cells.

Isolation of human marrow-derived mesenchymal stem cells.

Isolation of rat marrow-derived mesenchymal stem cells.

Clonal characterization of fibroblasts in the superficial layer of the adult human dermis.

Human mesenchymal stem cells signals regulate neural stem cell fate.

Cartilage tissue engineering for laryngotracheal reconstruction: comparison of chondrocytes from three anatomic locations in the rabbit.

Isolation and characterization of a population of immature dental pulp stem cells expressing OCT-4 and other embryonic stem cell markers.

Injectable biodegradable hydrogel composites for rabbit marrow mesenchymal stem cell and growth factor delivery for cartilage tissue engineering.

Adult mesenchymal stem cells for tissue engineering versus regenerative medicine.

A self-assembled fibroblast-endothelial cell co-culture system that supports in vitro vasculogenesis by both human umbilical vein endothelial cells and human dermal microvascular endothelial cells.

Human dermal fibroblast subpopulations; differential interactions with vascular endothelial cells in coculture: nonsoluble factors in the extracellular matrix influence interactions.

Effect of dual growth factor delivery on chondrogenic differentiation of rabbit marrow mesenchymal stem cells encapsulated in injectable hydrogel composites.

In search of the in vivo identity of mesenchymal stem cells.

Effects of initial seeding density and fluid perfusion rate on formation of tissue-engineered bone.

Dexamethasone inhibition of confluence-induced apoptosis in human mesenchymal stem cells.

All MSCs are pericytes?

MSC frequency correlates with blood vessel density in equine adipose tissue.

In vitro dexamethasone pretreatment enhances bone formation of human mesenchymal stem cells in vivo.

Effect of swelling ratio of injectable hydrogel composites on chondrogenic differentiation of encapsulated rabbit marrow mesenchymal stem cells in vitro.

Human bone marrow-derived mesenchymal stem cells induce Th2-polarized immune response and promote endogenous repair in animal models of multiple sclerosis.

Influence of adult mesenchymal stem cells on in vitro vascular formation.

New era of cell-based orthopedic therapies.

A point mutation in KINDLIN3 ablates activation of three integrin subfamilies in humans.

Fibroblasts-a diverse population at the center of it all.

Chondrogenesis of adult stem cells from adipose tissue and bone marrow: induction by growth factors and cartilage-derived matrix.

Optimizing mesenchymal stem cell-based therapeutics.

Fibroblast growth factor-2 enhances proliferation and delays loss of chondrogenic potential in human adult bone-marrow-derived mesenchymal stem cells.

Mechanisms involved in the therapeutic properties of mesenchymal stem cells.

Low oxygen tension during incubation periods of chondrocyte expansion is sufficient to enhance postexpansion chondrogenesis.

In vitro generation of mechanically functional cartilage grafts based on adult human stem cells and 3D-woven poly(epsilon-caprolactone) scaffolds.

The potential of mesenchymal stem cells for neural repair.

What's in a name?

Adult mesenchymal stem cells: an innovative therapeutic for lung diseases.

Chondrogenesis and mineralization during in vitro culture of human mesenchymal stem cells on three-dimensional woven scaffolds.

Human mesenchymal stem cells suppress chronic airway inflammation in the murine ovalbumin asthma model.

Topical delivery of mesenchymal stem cells and their function in wounds.

Age-related differences in human skin proteoglycans.

Defining human mesenchymal stem cell efficacy in vivo.

Mesenchymal stem cells: mechanisms of inflammation.

2010 lifetime achievement award of Tissue Engineering and Regenerative Medicine International Society--north America: Arnold I. Caplan, Ph.D.

Biological evaluation of a new C-xylopyranoside derivative (C-Xyloside) and its role in glycosaminoglycan biosynthesis.

PDGF in bone formation and regeneration: new insights into a novel mechanism involving MSCs.

The MSC: an injury drugstore.

Nondestructive evaluation of hydrogel mechanical properties using ultrasound.

Polybrene inhibits human mesenchymal stem cell proliferation during lentiviral transduction.

The creation of an in vitro adipose tissue that contains a vascular-adipocyte complex.

Stem cells in dental pulp of deciduous teeth.

Development of a peptide-targeted, myocardial ischemia-homing, mesenchymal stem cell.

Proteoglycans of uterine fibroids and keloid scars: similarity in their proteoglycan composition.

Imaging stem cell differentiation for cell-based tissue repair.

Hepatocyte growth factor mediates mesenchymal stem cell–induced recovery in multiple sclerosis models.

Quantitative microscopy in murine models of lung inflammation.

Scaling-up of dental pulp stem cells isolated from multiple niches.

The inhibition by interleukin 1 of MSC chondrogenesis and the development of biomechanical properties in biomimetic 3D woven PCL scaffolds.

Cell transplantation as an initiator of endogenous stem cell-based tissue repair.

Micrometer scale guidance of mesenchymal stem cells to form structurally oriented cartilage extracellular matrix.

The effect of extended first passage culture on the proliferation and differentiation of human marrow-derived mesenchymal stem cells.

Efficient lentiviral transduction of human mesenchymal stem cells that preserves proliferation and differentiation capabilities.

Adult mesenchymal stem cells and the NO pathways.

Growth, differentiation capacity, and function of mesenchymal stem cells expanded in serum-free medium developed via combinatorial screening.

The effects of crosslinking of scaffolds engineered from cartilage ECM on the chondrogenic differentiation of MSCs.

MSCs: Delivery Routes and Engraftment, Cell-Targeting Strategies, and Immune Modulation.

Mesenchymal stem cells in tissue repair.

Serial transplantation and long-term engraftment of intra-arterially delivered clonally derived mesenchymal stem cells to injured bone marrow.

Mesenchymal stem cells: environmentally responsive therapeutics for regenerative medicine.

Validating continuous digital light processing (cDLP) additive manufacturing accuracy and tissue engineering utility of a dye-initiator package.

Progressive approval: a proposal for a new regulatory pathway for regenerative medicine.

Chondrogenic differentiation of mesenchymal stem cells: challenges and unfulfilled expectations.

The role of CXCL12 and CCL7 chemokines in immune regulation, embryonic development, and tissue regeneration.

Identification of a subpopulation of marrow MSC-derived medullary adipocytes that express osteoclast-regulating molecules: marrow adipocytes express osteoclast mediators.

Cancer stem cells: targeting the roots of cancer, seeds of metastasis, and sources of therapy resistance.

Adult mesenchymal stem cells and women's health.

Regenerative treatments to enhance orthopedic surgical outcome.

Platelet-Derived Growth Factor BB Enhances Osteogenesis of Adipose-Derived But Not Bone Marrow-Derived Mesenchymal Stromal/Stem Cells.

Body Management: Mesenchymal Stem Cells Control the Internal Regenerator.

Mesenchymal Stem Cells: The Past, the Present, the Future.

The MSC curtain that stops the immune system.

Mesenchymal stem cells regulate melanoma cancer cells extravasation to bone and liver at their perivascular niche.

Adult Mesenchymal Stem Cells: When, Where, and How.

Mesenchymal stem cell therapy in a rat model of birth-trauma injury: functional improvements and biodistribution.

Proteoglycans in Leiomyoma and Normal Myometrium: Abundance, Steroid Hormone Control, and Implications for Pathophysiology.

MSCs: The Sentinel and Safe-Guards of Injury.

Antimicrobial Properties of Mesenchymal Stem Cells: Therapeutic Potential for Cystic Fibrosis Infection, and Treatment.

Development of a Functional Biomarker for Use in Cell-Based Therapy Studies in Seropositive Rheumatoid Arthritis.

Mesenchymal Stem Cells in Lipogems, a Reverse Story: from Clinical Practice to Basic Science.

The 3Rs of Cell Therapy.

Growth Factor Dose Tuning for Bone Progenitor Cell Proliferation and Differentiation on Resorbable Poly(propylene fumarate) Scaffolds.

The 3Rs of Cell Therapy.

New MSC: MSCs as pericytes are Sentinels and gatekeepers.

Mesenchymal Stem Cells: Time to Change the Name!

Not Missing the Future: A Call to Action for Investigating the Role of Regenerative Medicine Therapies in Pediatric/Adolescent Sports Injuries.

Transcriptome-Wide Analyses of Human Neonatal Articular Cartilage and Human Mesenchymal Stem Cell-Derived Cartilage Provide a New Molecular Target for Evaluating Engineered Cartilage.

Non-destructive/non-invasive imaging evaluation of cellular differentiation progression during in vitro MSC-derived chondrogenesis.