Fabio Cominelli

Intestinal ischemia and peripheral gangrene in a patient with chronic renal failure.

A possible role of IL-1ra 3'-untranslated region in modulation of protein production.

Effect of misoprostol on ibuprofen-induced renal dysfunction in patients with decompensated cirrhosis: results of a double-blind placebo-controlled parallel group study.

Down-regulation of intestinal lymphocyte activation and Th1 cytokine production by antibiotic therapy in a murine model of Crohn's disease.

Genetic dissection of the cellular pathways and signaling mechanisms in modeled tumor necrosis factor-induced Crohn's-like inflammatory bowel disease.

Emergence of perianal fistulizing disease in the SAMP1/YitFc mouse, a spontaneous model of chronic ileitis.

Mouse models for the study of Crohn's disease.

TNF-alpha neutralization ameliorates the severity of murine Crohn's-like ileitis by abrogation of intestinal epithelial cell apoptosis.

Identification of a quantitative trait locus for ileitis in a spontaneous mouse model of Crohn's disease: SAMP1/YitFc.

Expression, localization, and functional activity of TL1A, a novel Th1-polarizing cytokine in inflammatory bowel disease.

Future therapies for inflammatory bowel disease.

The Th1 immune pathway as a therapeutic target in Crohn's disease.

Effect of digestive health care services integration on resource use and outcomes in patients with digestive disorders.

Optimal dosing of 5-aminosalicylic acid: 5 decades of choosing between politicians.

Differential contribution of IL-1Ra isoforms to allele-specific IL-1Ra mRNA accumulation.

Expanded B cell population blocks regulatory T cells and exacerbates ileitis in a murine model of Crohn disease.

Cytokine-based therapies for Crohn's disease--new paradigms.

Linkage to peroxisome proliferator-activated receptor-gamma in SAMP1/YitFc mice and in human Crohn's disease.

L-selectin, alpha 4 beta 1, and alpha 4 beta 7 integrins participate in CD4+ T cell recruitment to chronically inflamed small intestine.

Proinflammatory effects of TH2 cytokines in a murine model of chronic small intestinal inflammation.

Altered epithelial cell lineage allocation and global expansion of the crypt epithelial stem cell population are associated with ileitis in SAMP1/YitFc mice.

Activation of A2A adenosine receptor attenuates intestinal inflammation in animal models of inflammatory bowel disease.

New concepts in the pathophysiology of inflammatory bowel disease.

Targeting mucosal addressin cellular adhesion molecule (MAdCAM)-1 to noninvasively image experimental Crohn's disease.

The primary defect in experimental ileitis originates from a nonhematopoietic source.

Critical role of endothelial P-selectin glycoprotein ligand 1 in chronic murine ileitis.

Role of TL1A and its receptor DR3 in two models of chronic murine ileitis.

Novel strategies to attenuate immune activation in Crohn's disease.

Do patient preferences influence decisions on treatment for patients with steroid-refractory ulcerative colitis?

Absence of bacterially induced RELMbeta reduces injury in the dextran sodium sulfate model of colitis.

Antibody blockade of CCL25/CCR9 ameliorates early but not late chronic murine ileitis.

Cytokine therapy for Crohn's disease: advances in translational research.

Commensal bacteria exacerbate intestinal inflammation but are not essential for the development of murine ileitis.

The attrition of young physician-scientists: problems and potential solutions.

Cloning IL-1 and the birth of a new era in cytokine biology.

Report of the American Gastroenterological Association (AGA) Institute Obesity Task Force.

Immunopathogenesis of inflammatory bowel disease: current concepts.

Resistin-like molecule beta (RELMbeta/FIZZ2) is highly expressed in the ileum of SAMP1/YitFc mice and is associated with initiation of ileitis.

MNK kinases regulate multiple TLR pathways and innate proinflammatory cytokines in macrophages.

A CD8+/CD103high T cell subset regulates TNF-mediated chronic murine ileitis.

Early and late gut immune responses in IBD.

Innate and adaptive immune responses related to IBD pathogenesis.

Commensal bacteria and "oncologic surveillance": suggestions from an experimental model.

AGA Institute Future Trends Committee report: the future of gastroenterology training programs in the United States.

Emerging drugs for the treatment of ulcerative colitis.

Probiotics promote gut health through stimulation of epithelial innate immunity.

Beta7 integrin deficiency suppresses B cell homing and attenuates chronic ileitis in SAMP1/YitFc mice.

SAMP1/YitFc mouse strain: a spontaneous model of Crohn's disease-like ileitis.

Spontaneous, immune-mediated gastric inflammation in SAMP1/YitFc mice, a model of Crohn's-like gastritis.

A multicenter retrospective experience of infliximab in Crohn's disease patients: infusion reaction rates and treatment persistency.

New insights into the dichotomous role of innate cytokines in gut homeostasis and inflammation.

Probiotic bacteria regulate intestinal epithelial permeability in experimental ileitis by a TNF-dependent mechanism.

Vercirnon for the treatment of Crohn's disease.

RIP2 activity in inflammatory disease and implications for novel therapeutics.

Inhibition of leukocyte trafficking in inflammatory bowel disease.

Intestinal-Specific TNFα Overexpression Induces Crohn's-Like Ileitis in Mice.

Dysregulated NOD2 predisposes SAMP1/YitFc mice to chronic intestinal inflammation.

The tumor necrosis factor-like cytokine 1A/death receptor 3 cytokine system in intestinal inflammation.

Functional defects in NOD2 signaling in experimental and human Crohn disease.

Inflammatory bowel disease.

Occurrence of spontaneous periodontal disease in the SAMP1/YitFc murine model of Crohn disease.

The dual role of nod-like receptors in mucosal innate immunity and chronic intestinal inflammation.

Cytokines and mucosal immunity.

In vivo inhibition of RIPK2 kinase alleviates inflammatory disease.

Safety considerations when using anti-TNFα therapy to treat Crohn's disease.

Ulcerative Colitis: What is the Optimal Treatment Goal and How Do We Achieve It?

SAMP1/YitFc mice develop ileitis via loss of CCL21 and defects in dendritic cell migration.

TISSUE REGENERATION. Inhibition of the prostaglandin-degrading enzyme 15-PGDH potentiates tissue regeneration.

Stereomicroscopic 3D-pattern profiling of murine and human intestinal inflammation reveals unique structural phenotypes.

Dysregulated intrahepatic CD4(+) T-cell activation drives liver inflammation in ileitis-prone SAMP1/YitFc mice.

Association Between Inflammatory Bowel Disease and Vitamin D Deficiency: A Systematic Review and Meta-analysis.

Role of type 2 immunity in intestinal inflammation.

Pathway-based approaches to the treatment of inflammatory bowel disease.

IL-33 Drives Eosinophil Infiltration and Pathogenic Type 2 Helper T-Cell Immune Responses Leading to Chronic Experimental Ileitis.

Colitis-Associated and Sporadic Colon Cancers: Different Diseases, Different Mutations?

A Novel Role for TL1A/DR3 in Protection against Intestinal Injury and Infection.

Mucosal Interactions between Genetics, Diet, and Microbiome in Inflammatory Bowel Disease.

Clinical Effects of Gamma-Radiation-Resistant Aspergillus sydowii on Germ-Free Mice Immunologically Prone to Inflammatory Bowel Disease.

Protective Role for TWEAK/Fn14 in Regulating Acute Intestinal Inflammation and Colitis-Associated Tumorigenesis.

Fucosylation Deficiency in Mice Leads to Colitis and Adenocarcinoma.

Cytokines and intestinal inflammation.

Our Vision for the Future of Inflammatory Bowel Diseases: Research, Innovations, and Controversies.

Mesenchymal stem/stromal cell therapy for inflammatory bowel disease: an updated review with maintenance of remission.

Epithelial-specific Toll-like Receptor (TLR)5 Activation Mediates Barrier Dysfunction in Experimental Ileitis.

A novel model of colitis-associated cancer in SAMP1/YitFc mice with Crohn's disease-like ileitis.

Uncovering Pathogenic Mechanisms of Inflammatory Bowel Disease Using Mouse Models of Crohn's Disease-Like Ileitis: What is the Right Model?

A guiding map for inflammation.