Karthik Nagapudi

Photo-cross-linking of type I collagen gels in the presence of smooth muscle cells: mechanical properties, cell viability, and function.

Viscoelastic and mechanical behavior of recombinant protein elastomers.

Alterations in physical cross-linking modulate mechanical properties of two-phase protein polymer networks.

Quantification of compaction-induced crystallinity reduction of a pharmaceutical solid using 19F solid-state NMR and powder X-ray diffraction.

Manufacture of pharmaceutical co-crystals using twin screw extrusion: a solvent-less and scalable process.

Fast surface crystallization of amorphous griseofulvin below T g.

Selective and potent Raf inhibitors paradoxically stimulate normal cell proliferation and tumor growth.

Manufacture and performance evaluation of a stable amorphous complex of an acidic drug molecule and Neusilin.

High-throughput 96-well solvent mediated sonic blending synthesis and on-plate solid/solution stability characterization of pharmaceutical cocrystals.

Crystal structure study and investigation of solid-state cyclization for AMG 222, a channel hydrate.

Effect of pH and excipients on structure, dynamics, and long-term stability of a model IgG1 monoclonal antibody upon freeze-drying.

Application of twin screw extrusion in the manufacture of cocrystals, part I: four case studies.

Structural studies of a non-stoichiometric channel hydrate using high resolution X-ray powder diffraction, solid-state nuclear magnetic resonance, and moisture sorption methods.

Sorbitol crystallization-induced aggregation in frozen mAb formulations.

Application of twin screw extrusion to the manufacture of cocrystals: scale-up of AMG 517-sorbic acid cocrystal production.

Amorphous solid dispersions: a robust platform to address bioavailability challenges.

Application of (19)  F time-domain NMR to measure content in fluorine-containing drug products.

Conformational isomerism in solid state of AMG 853--structure studies using solid-state nuclear magnetic resonance and X-ray diffraction.

Investigation of Phase Mixing in Amorphous Solid Dispersions of AMG 517 in HPMC-AS Using DSC, Solid-State NMR, and Solution Calorimetry.

A rational approach towards development of amorphous solid dispersions: Experimental and computational techniques.

Control Strategies for Drug Product Continuous Direct Compression-State of Control, Product Collection Strategies, and Startup/Shutdown Operations for the Production of Clinical Trial Materials and Commercial Products.

Humidity induced phase transformation of poloxamer 188 and its effect on physical stability of amorphous solid dispersion of AMG 579, a PDE10A inhibitor.

High-throughput screening and scale-up of cocrystals using resonant acoustic mixing.