Christophe Vanpouille

Interactions between human immunodeficiency virus type 1 and vaccinia virus in human lymphoid tissue ex vivo.

Acyclovir is activated into a HIV-1 reverse transcriptase inhibitor in herpesvirus-infected human tissues.

A highly sensitive and dynamic immunofluorescent cytometric bead assay for the detection of HIV-1 p24.

Coinfecting viruses as determinants of HIV disease.

Mechanisms associated with HIV-1 resistance to acyclovir by the V75I mutation in reverse transcriptase.

The application of phosphoramidate protide technology to acyclovir confers anti-HIV inhibition.

A missed point in deciphering the viral synergy between herpes simplex virus and HIV.

Acyclovir: a new use for an old drug.

War and peace between microbes: HIV-1 interactions with coinfecting viruses.

A new class of dual-targeted antivirals: monophosphorylated acyclovir prodrug derivatives suppress both human immunodeficiency virus type 1 and herpes simplex virus type 2.

HIV-1 sexual transmission: early events of HIV-1 infection of human cervico-vaginal tissue in an optimized ex vivo model.

Contrasting roles for TLR ligands in HIV-1 pathogenesis.

Cervico-vaginal tissue ex vivo as a model to study early events in HIV-1 infection.

Topical tenofovir, a microbicide effective against HIV, inhibits herpes simplex virus-2 replication.

Semen of HIV-1-infected individuals: local shedding of herpesviruses and reprogrammed cytokine network.

Exploiting the anti-HIV-1 activity of acyclovir: suppression of primary and drug-resistant HIV isolates and potentiation of the activity by ribavirin.

Microbicides: still a long road to success.

HIV-1 imposes rigidity on blood and semen cytokine networks.

Interleukin-7 facilitates HIV-1 transmission to cervico-vaginal tissue ex vivo.

A multi-targeted drug candidate with dual anti-HIV and anti-HSV activity.

Histocultures (tissue explants) in human retrovirology.

Design, synthesis and biological evaluation of phosphorodiamidate prodrugs of antiviral and anticancer nucleosides.

A new antiviral: chimeric 3TC-AZT phosphonate efficiently inhibits HIV-1 in human tissues ex vivo.

Valacyclovir Decreases Plasma HIV-1 RNA in HSV-2 Seronegative Individuals: A Randomized Placebo-Controlled Crossover Trial.

Genital Cytomegalovirus Replication Predicts Syphilis Acquisition among HIV-1 Infected Men Who Have Sex with Men.

Distinct cytokine/chemokine network in semen and blood characterize different stages of HIV infection.

Standardization of a cytometric p24-capture bead-assay for the detection of main HIV-1 subtypes.

HIV Trafficking Between Blood and Semen During Early Untreated HIV Infection.

Monocytes but Not Lymphocytes Carrying HIV-1 on Their Surface Transmit Infection to Human Tissue Ex Vivo.

Extracellular Vesicles Carry HIV Env and Facilitate Hiv Infection of Human Lymphoid Tissue.

Vaginal Inhibits HIV-1 Replication in Human Tissues .

A common anti-cytomegalovirus drug, ganciclovir, inhibits HIV-1 replication in human tissues ex vivo.

Dual-targeted anti-TB/anti-HIV heterodimers.

Virtual Screening of Acyclovir Derivatives as Potential Antiviral Agents: Design, Synthesis, and Biological Evaluation of New Acyclic Nucleoside ProTides.

Cytomegalovirus and HIV Persistence: Pouring Gas on the Fire.

Histoculture and Infection with HIV of Functional Human Lymphoid Tissue on Gelfoam.

Human cytomegalovirus-infected cells release extracellular vesicles that carry viral surface proteins.