Department of Clinical Laboratory Sciences and Medical Biotechnology,
College of Medicine,
Department of Clinical Laboratory Sciences and Medical Biotechnology, College of Medicine
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Dichloromethane extracts of propolis protect cell from oxygen-glucose deprivation-induced oxidative stress via reducing apoptosis.
Food & nutrition research , 2016 | Pubmed ID: 27329777
The emergence of T790M mutation in EGFR-mutant lung adenocarcinoma patients having a history of acquired resistance to EGFR-TKI: focus on rebiopsy timing and long-term existence of T790M.
Oncotarget Jul, 2016 | Pubmed ID: 27384480
Decreased expressions of hepsin in human hepatocellular carcinomas.
Liver international : official journal of the International Association for the Study of the Liver Sep, 2006 | Pubmed ID: 16911458
Mice deficient in collapsin response mediator protein-1 exhibit impaired long-term potentiation and impaired spatial learning and memory.
The Journal of neuroscience : the official journal of the Society for Neuroscience Mar, 2007 | Pubmed ID: 17344389
Enterovirus-induced miR-141 contributes to shutoff of host protein translation by targeting the translation initiation factor eIF4E.
Cell host & microbe Jan, 2011 | Pubmed ID: 21238947
Clustered genomic alterations in chromosome 7p dictate outcomes and targeted treatment responses of lung adenocarcinoma with EGFR-activating mutations.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology Sep, 2011 | Pubmed ID: 21810691
Serine protease hepsin regulates hepatocyte size and hemodynamic retention of tumor cells by hepatocyte growth factor signaling in mice.
Hepatology (Baltimore, Md.) Nov, 2012 | Pubmed ID: 22505209
Rutin, a Flavonoid That Is a Main Component of Saussurea involucrata, Attenuates the Senescence Effect in D-Galactose Aging Mouse Model.
Evidence-based complementary and alternative medicine : eCAM , 2012 | Pubmed ID: 22952557
Potential Therapeutic Role of Z-Isochaihulactone in Lung Cancer through Induction of Apoptosis via Notch Signaling.
Evidence-based complementary and alternative medicine : eCAM , 2012 | Pubmed ID: 23049612
R26R-GR: a Cre-activable dual fluorescent protein reporter mouse.
PloS one , 2012 | Pubmed ID: 23049968
Potential Therapeutic Role of Hispidulin in Gastric Cancer through Induction of Apoptosis via NAG-1 Signaling.
Evidence-based complementary and alternative medicine : eCAM , 2013 | Pubmed ID: 24159347
3,4-Dihydroxytoluene, a metabolite of rutin, inhibits inflammatory responses in lipopolysaccharide-activated macrophages by reducing the activation of NF-κB signaling.
BMC complementary and alternative medicine Jan, 2014 | Pubmed ID: 24417898
Taiwanese Green Propolis and Propolin G Protect the Liver from the Pathogenesis of Fibrosis via Eliminating TGF-β-Induced Smad2/3 Phosphorylation.
Journal of agricultural and food chemistry Mar, 2014 | Pubmed ID: 24625297
Rutin, a flavonoid and principal component of saussurea involucrata, attenuates physical fatigue in a forced swimming mouse model.
International journal of medical sciences , 2014 | Pubmed ID: 24693223
Prior EGFR tyrosine-kinase inhibitor therapy did not influence the efficacy of subsequent pemetrexed plus platinum in advanced chemonaïve patients with EGFR-mutant lung adenocarcinoma.
OncoTargets and therapy , 2014 | Pubmed ID: 24920920
Impact of EGFR mutation detection methods on the efficacy of erlotinib in patients with advanced EGFR-wild type lung adenocarcinoma.
PloS one , 2014 | Pubmed ID: 25215536
Dynamic plasma EGFR mutation status as a predictor of EGFR-TKI efficacy in patients with EGFR-mutant lung adenocarcinoma.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer Apr, 2015 | Pubmed ID: 25514801
Identification of five driver gene mutations in patients with treatment-naïve lung adenocarcinoma in Taiwan.
PloS one , 2015 | Pubmed ID: 25789627
HOXA5 inhibits metastasis via regulating cytoskeletal remodelling and associates with prolonged survival in non-small-cell lung carcinoma.
PloS one , 2015 | Pubmed ID: 25875824
R331W Missense Mutation of Oncogene YAP1 Is a Germline Risk Allele for Lung Adenocarcinoma With Medical Actionability.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology Jul, 2015 | Pubmed ID: 26056182
Small Molecule T315 Promotes Casitas B-Lineage Lymphoma-Dependent Degradation of Epidermal Growth Factor Receptor via Y1045 Autophosphorylation.
American journal of respiratory and critical care medicine Apr, 2016 | Pubmed ID: 26583948
EGFR mutation and lobar location of lung adenocarcinoma.
Carcinogenesis Feb, 2016 | Pubmed ID: 26645716
Predilection of contralateral upper lung metastasis in upper lobe lung adenocarcinoma patients.
Journal of thoracic disease Jan, 2016 | Pubmed ID: 26904216
JAG1 Is Associated with Poor Survival through Inducing Metastasis in Lung Cancer.
PloS one , 2016 | Pubmed ID: 26930648
Coexistence of EGFR T790M mutation and common activating mutations in pretreatment non-small cell lung cancer: A systematic review and meta-analysis.
Lung cancer (Amsterdam, Netherlands) Apr, 2016 | Pubmed ID: 26973206
SPANXA suppresses EMT by inhibiting c-JUN/SNAI2 signaling in lung adenocarcinoma.
Oncotarget Jul, 2016 | Pubmed ID: 27323831
Molecular gene signature and prognosis of non-small cell lung cancer.
Oncotarget Aug, 2016 | Pubmed ID: 27437769
Higher frequency but random distribution of EGFR mutation subtypes in familial lung cancer patients.
Oncotarget Aug, 2016 | Pubmed ID: 27449093
Implementation and Quality Control of Lung Cancer EGFR Genetic Testing by MALDI-TOF Mass Spectrometry in Taiwan Clinical Practice.
Scientific reports 08, 2016 | Pubmed ID: 27480787
Gene expression of MAGE-A3 and PRAME tumor antigens and EGFR mutational status in Taiwanese non-small cell lung cancer patients.
Asia-Pacific journal of clinical oncology Oct, 2017 | Pubmed ID: 27519286
Rapid Sputum Multiplex Detection of the M. tuberculosis Complex (MTBC) and Resistance Mutations for Eight Antibiotics by Nucleotide MALDI-TOF MS.
Scientific reports Jan, 2017 | Pubmed ID: 28134321
FAM198B is Associated with Prolonged Survival and Inhibits Metastasis in Lung Adenocarcinoma via Blockage of ERK-Mediated MMP-1 Expression.
Clinical cancer research : an official journal of the American Association for Cancer Research Dec, 2017 | Pubmed ID: 29217529
Application of single nucleotide extension and MALDI-TOF mass spectrometry in proofreading and DNA repair assay.
DNA repair 01, 2018 | Pubmed ID: 29223016
Intercalated Treatment Following Rebiopsy Is Associated with a Shorter Progression-Free Survival of Osimertinib Treatment.
Cancer research and treatment : official journal of Korean Cancer Association Dec, 2017 | Pubmed ID: 29228521
EGFR mutation, smoking, and gender in advanced lung adenocarcinoma.
Oncotarget Nov, 2017 | Pubmed ID: 29228697
Outcomes in patients with non-small-cell lung cancer and acquired Thr790Met mutation treated with osimertinib: a genomic study.
The Lancet. Respiratory medicine 02, 2018 | Pubmed ID: 29249325
The Association of Acquired T790M Mutation with Clinical Characteristics after Resistance to First-Line Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor in Lung Adenocarcinoma.
Cancer research and treatment : official journal of Korean Cancer Association Jan, 2018 | Pubmed ID: 29334606
DNA polymerase I proofreading exonuclease activity is required for endonuclease V repair pathway both in vitro and in vivo.
DNA repair 04, 2018 | Pubmed ID: 29522920
Characteristics and Predictive Value of PD-L1 Status in Real-World Non-Small Cell Lung Cancer Patients.
Journal of immunotherapy (Hagerstown, Md. : 1997) Jul/Aug, 2018 | Pubmed ID: 29683890
Novel therapeutic drug identification and gene correlation for fatty liver disease using high-content screening: Proof of concept.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences May, 2018 | Pubmed ID: 29800612
Tumor PD-L1 Expression and Clinical Outcomes in Advanced-stage Non-Small Cell Lung Cancer Patients Treated with Nivolumab or Pembrolizumab: Real-World Data in Taiwan.
Journal of Cancer , 2018 | Pubmed ID: 29805708
Clinicopathological and genomic comparisons between different histologic components in combined small cell lung cancer and non-small cell lung cancer.
Lung cancer (Amsterdam, Netherlands) 11, 2018 | Pubmed ID: 30429033
Mutational monitoring of EGFR T790M in cfDNA for clinical outcome prediction in EGFR-mutant lung adenocarcinoma.
PloS one , 2018 | Pubmed ID: 30444875
Perinatal polychlorinated biphenyls and polychlorinated dibenzofurans exposure are associated with DNA methylation changes lasting to early adulthood: Findings from Yucheng second generation.
Environmental research 03, 2019 | Pubmed ID: 30640082
High PD-L1 expression correlates with primary resistance to EGFR-TKIs in treatment naïve advanced EGFR-mutant lung adenocarcinoma patients.
Lung cancer (Amsterdam, Netherlands) 01, 2019 | Pubmed ID: 30642549
Improved Dried Blood Spot-Based Metabolomics Analysis by a Postcolumn Infused-Internal Standard Assisted Liquid Chromatography-Electrospray Ionization Mass Spectrometry Method.
Analytical chemistry 08, 2019 | Pubmed ID: 31361473
Metabolomics Investigation of Voriconazole-Induced Hepatotoxicity in Mice.
Chemical research in toxicology 09, 2019 | Pubmed ID: 31411454
Association between programmed death-ligand 1 expression, immune microenvironments, and clinical outcomes in epidermal growth factor receptor mutant lung adenocarcinoma patients treated with tyrosine kinase inhibitors.
European journal of cancer (Oxford, England : 1990) 01, 2020 | Pubmed ID: 31760310
Proofreading of single nucleotide insertion/deletion replication errors analyzed by MALDI-TOF mass spectrometry assay.
DNA repair 04, 2020 | Pubmed ID: 32036259
Association of Programmed Death-Ligand 1 Expression with Fusion Variants and Clinical Outcomes in Patients with Anaplastic Lymphoma Kinase-Positive Lung Adenocarcinoma Receiving Crizotinib.
The oncologist 08, 2020 | Pubmed ID: 32386255
Copy Number Alterations of Depressed Colorectal Neoplasm Predict the Survival and Response to Oxaliplatin in Proximal Colon Cancer.
Cancers Jun, 2020 | Pubmed ID: 32532105
Proteogenomics of Non-smoking Lung Cancer in East Asia Delineates Molecular Signatures of Pathogenesis and Progression.
Cell 07, 2020 | Pubmed ID: 32649875
Primary Tumor Resection Is Associated with a Better Outcome among Advanced EGFR-Mutant Lung Adenocarcinoma Patients Receiving EGFR-TKI Treatment.
Oncology , 2021 | Pubmed ID: 32894845
Measurement of uracil-DNA glycosylase activity by matrix assisted laser desorption/ionization time-of-flight mass spectrometry technique.
DNA repair 01, 2021 | Pubmed ID: 33254084
ALK variants, PD-L1 expression, and their association with outcomes in ALK-positive NSCLC patients.
Scientific reports 12, 2020 | Pubmed ID: 33273548
The impact of different first-line EGFR-TKIs on the clinical outcome of sequential osimertinib treatment in advanced NSCLC with secondary T790M.
Scientific reports 06, 2021 | Pubmed ID: 34103652
The Clinical Outcomes of Different First-Line EGFR-TKIs Plus Bevacizumab in Advanced EGFR-Mutant Lung Adenocarcinoma.
Cancer research and treatment Apr, 2022 | Pubmed ID: 34352999
Publisher Correction: The impact of different first-line EGFR-TKIs on the clinical outcome of sequential osimertinib treatment in advanced NSCLC with secondary T790M.
Scientific reports Aug, 2021 | Pubmed ID: 34462521
Transthyretin as a Biomarker to Predict and Monitor Major Depressive Disorder Identified by Whole-Genome Transcriptomic Analysis in Mouse Models.
Biomedicines Aug, 2021 | Pubmed ID: 34572310
Prognostic Characteristics and Immunotherapy Response of Patients With Nonsquamous NSCLC With Mutation in East Asian Populations: A Single-Center Cohort Study in Taiwan.
JTO clinical and research reports Feb, 2021 | Pubmed ID: 34589991
Novel Genetic Prognostic Signature for Lung Adenocarcinoma Identified by Differences in Gene Expression Profiles of Low- and High-Grade Histological Subtypes.
Biomolecules Jan, 2022 | Pubmed ID: 35204661
Genetic Deletion of HLJ1 Does Not Affect Blood Coagulation in Mice.
International journal of molecular sciences Feb, 2022 | Pubmed ID: 35216179
Kang-Yi Su*,1,2,
Steven D. Goodman*,3,
Hung-Ming Lai1,
Rong-Syuan Yen1,
Wei-Yao Hu1,
Wern-Cherng Cheng2,
Liang-In Lin1,2,
Ya-Chien Yang1,2,
Woei-Horng Fang1,2
1Department of Clinical Laboratory Sciences and Medical Biotechnology, College of Medicine, National Taiwan University,
2Department of Laboratory Medicine, National Taiwan University Hospital,
3Center for Microbial Pathogenesis, Nationwide Children's Hospital and the Department of Pediatrics, The Ohio State University
Hui-Lan Chang*,1,
Kang-Yi Su*,1,2,
Steven D. Goodman3,
Wern-Cherng Cheng2,
Liang-In Lin1,2,
Ya-Chien Yang1,2,
Sui-Yuan Chang1,2,
Woei-horng Fang1,2
1Department of Clinical Laboratory Sciences and Medical Biotechnology, College of Medicine, National Taiwan University,
2Department of Laboratory Medicine, National Taiwan University Hospital,
3Center for Microbial Pathogenesis, Nationwide Children’s Hospital and the Department of Pediatrics, The Ohio State University