Jeanho Yun

Hypersensitivity of Brca1-deficient MEF to the DNA interstrand crosslinking agent mitomycin C is associated with defect in homologous recombination repair and aberrant S-phase arrest.

Serum amyloid A stimulates matrix-metalloproteinase-9 upregulation via formyl peptide receptor like-1-mediated signaling in human monocytic cells.

Lysophosphatidic acid stimulates cell proliferation in rat chondrocytes.

Sphingosine-1-phosphate stimulates rat primary chondrocyte proliferation.

Serum amyloid A induces WISH cell apoptosis.

Phytosphingosine-1-phosphate stimulates chemotactic migration of L2071 mouse fibroblasts via pertussis toxin-sensitive G-proteins.

Identification of novel substrates for human checkpoint kinase Chk1 and Chk2 through genome-wide screening using a consensus Chk phosphorylation motif.

Alkylating agent methyl methanesulfonate (MMS) induces a wave of global protein hyperacetylation: implications in cancer cell death.

Lysophosphatidylethanolamine stimulates chemotactic migration and cellular invasion in SK-OV3 human ovarian cancer cells: involvement of pertussis toxin-sensitive G-protein coupled receptor.

Lysophosphatidylglycerol stimulates chemotactic migration in human natural killer cells.

Lysophosphatidylserine stimulates chemotactic migration in U87 human glioma cells.

Nek6 is involved in G2/M phase cell cycle arrest through DNA damage-induced phosphorylation.

Serum amyloid A induces CCL2 production via formyl peptide receptor-like 1-mediated signaling in human monocytes.

Collagen-binding motif peptide, a cleavage product of osteopontin, stimulates human neutrophil chemotaxis via pertussis toxin-sensitive G protein-mediated signaling.

Activation of formyl peptide receptor like-1 by serum amyloid A induces CCL2 production in human umbilical vein endothelial cells.

LL-37 inhibits serum amyloid A-induced IL-8 production in human neutrophils.

UV light induces premature senescence in Akt1-null mouse embryonic fibroblasts by increasing intracellular levels of ROS.

Lysophosphatidylglycerol inhibits formyl peptide receptorlike-1-stimulated chemotactic migration and IL-1beta production from human phagocytes.

Functional expression of formyl peptide receptor family in human NK cells.

A pertussis toxin sensitive G-protein-independent pathway is involved in serum amyloid A-induced formyl peptide receptor 2-mediated CCL2 production.

Fenofibrate antagonizes Chk2 activation by inducing Wip1 expression: implications for cell proliferation and tumorigenesis.

A different TRAP220 expression in distinct histologic subtypes of lung adenocarcinoma and the prognostic significance.

Nek6 overexpression antagonizes p53-induced senescence in human cancer cells.

Glucose deprivation is associated with Chk1 degradation through the ubiquitin-proteasome pathway and effective checkpoint response to replication blocks.

Nek6 suppresses the premature senescence of human cancer cells induced by camptothecin and doxorubicin treatment.

DNA damage induces down-regulation of PEPCK and G6P gene expression through degradation of PGC-1alpha.

Loss of Med1/TRAP220 promotes the invasion and metastasis of human non-small-cell lung cancer cells by modulating the expression of metastasis-related genes.

Melatonin suppresses doxorubicin-induced premature senescence of A549 lung cancer cells by ameliorating mitochondrial dysfunction.

p21(WAF¹/C¹P¹) deficiency induces mitochondrial dysfunction in HCT116 colon cancer cells.

The inhibition of Nek6 function sensitizes human cancer cells to premature senescence upon serum reduction or anticancer drug treatment.

p53 interferes with microtubule-stabilizing agent-induced apoptosis in prostate and colorectal cancer cells.

Mitohormesis.

Clinical Significance of Peroxisome Proliferator-Activated Receptor γ and TRAP220 in Patients with Operable Colorectal Cancer.

Targeted inhibition of mitochondrial Hsp90 induces mitochondrial elongation in Hep3B hepatocellular carcinoma cells undergoing apoptosis by increasing the ROS level.

Measuring In Vivo Mitophagy.

Akt3 knockdown induces mitochondrial dysfunction in human cancer cells.

HO-1 inhibits preadipocyte proliferation and differentiation at the onset of obesity via ROS dependent activation of Akt2.

Ethanol extract of the seed of Zizyphus jujuba var. spinosa potentiates hippocampal synaptic transmission through mitogen-activated protein kinase, adenylyl cyclase, and protein kinase A pathways.

Emerging role of mitophagy in human diseases and physiology.

Checkpoint-dependent phosphorylation of Med1/TRAP220 in response to DNA damage.

Cooperation between p21 and Akt is required for p53-dependent cellular senescence.

Downregulation of Drp1, a fission regulator, is associated with human lung and colon cancers.