Department of Pathology and Molecular Medicine
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Tumor suppressor LATS1 is a negative regulator of oncogene YAP.
The Journal of biological chemistry Feb, 2008 | Pubmed ID: 18158288
Molecular characterization of human homologs of yeast MOB1.
International journal of cancer May, 2010 | Pubmed ID: 19739119
Identification of LATS transcriptional targets in HeLa cells using whole human genome oligonucleotide microarray.
Gene Jan, 2010 | Pubmed ID: 19799973
MicroRNA-193b represses cell proliferation and regulates cyclin D1 in melanoma.
The American journal of pathology May, 2010 | Pubmed ID: 20304954
LATS tumor suppressor: a new governor of cellular homeostasis.
Cell cycle (Georgetown, Tex.) Oct, 2010 | Pubmed ID: 20935475
Taxol resistance in breast cancer cells is mediated by the hippo pathway component TAZ and its downstream transcriptional targets Cyr61 and CTGF.
Cancer research Apr, 2011 | Pubmed ID: 21349946
Itch E3 ubiquitin ligase regulates large tumor suppressor 1 stability [corrected].
Proceedings of the National Academy of Sciences of the United States of America Mar, 2011 | Pubmed ID: 21383157
Molecular mechanism of size control in development and human diseases.
Cell research May, 2011 | Pubmed ID: 21483452
LATS1 tumor suppressor is a novel actin-binding protein and negative regulator of actin polymerization.
Cell research Oct, 2011 | Pubmed ID: 21808298
miR-193b Regulates Mcl-1 in Melanoma.
The American journal of pathology Nov, 2011 | Pubmed ID: 21893020
Tumour suppressor genes in chemotherapeutic drug response.
Bioscience reports Aug, 2012 | Pubmed ID: 22762204
Cell surface expression of human ether-a-go-go-related gene (hERG) channels is regulated by caveolin-3 protein via the ubiquitin ligase Nedd4-2.
The Journal of biological chemistry Sep, 2012 | Pubmed ID: 22879586
WWP1 E3 ligase targets LATS1 for ubiquitin-mediated degradation in breast cancer cells.
PloS one , 2013 | Pubmed ID: 23573293
BMP4 is a novel transcriptional target and mediator of mammary cell migration downstream of the Hippo pathway component TAZ.
Cellular signalling Aug, 2013 | Pubmed ID: 23673366
Fer protein-tyrosine kinase promotes lung adenocarcinoma cell invasion and tumor metastasis.
Molecular cancer research : MCR Aug, 2013 | Pubmed ID: 23699534
YAP-induced resistance of cancer cells to antitubulin drugs is modulated by a Hippo-independent pathway.
Cancer research Aug, 2014 | Pubmed ID: 24812269
The Hippo pathway in chemotherapeutic drug resistance.
International journal of cancer Dec, 2015 | Pubmed ID: 25348697
Roles of the Hippo pathway in lung development and tumorigenesis.
International journal of cancer Feb, 2016 | Pubmed ID: 25644176
Recombinant hamster oviductin is biologically active and exerts positive effects on sperm functions and sperm-oocyte binding.
PloS one , 2015 | Pubmed ID: 25849110
Hippo Component TAZ Functions as a Co-repressor and Negatively Regulates ΔNp63 Transcription through TEA Domain (TEAD) Transcription Factor.
The Journal of biological chemistry Jul, 2015 | Pubmed ID: 25995450
Regulation of sensitivity of tumor cells to antitubulin drugs by Cdk1-TAZ signalling.
Oncotarget Sep, 2015 | Pubmed ID: 26183396
WWTR1 (WW domain containing transcription regulator 1).
Atlas of genetics and cytogenetics in oncology and haematology Nov, 2014 | Pubmed ID: 26366208
The roles of the Hippo pathway in cancer metastasis.
Cellular signalling 11, 2016 | Pubmed ID: 27519476
TAZ induces lung cancer stem cell properties and tumorigenesis by up-regulating ALDH1A1.
Oncotarget Jun, 2017 | Pubmed ID: 28415606
Essential signaling in loss-related tumours: the therapeutic potential of CRL4 and mTOR combined inhibition.
Journal of thoracic disease Oct, 2017 | Pubmed ID: 29268334
The Hippo Pathway Component TAZ Promotes Immune Evasion in Human Cancer through PD-L1.
Cancer research Mar, 2018 | Pubmed ID: 29339539
Cysteine residues are essential for dimerization of Hippo pathway components YAP2L and TAZ.
Scientific reports Feb, 2018 | Pubmed ID: 29472569
Identification of Cdk1-LATS-Pin1 as a Novel Signaling Axis in Anti-tubulin Drug Response of Cancer Cells.
Molecular cancer research : MCR Jun, 2018 | Pubmed ID: 29523761
A LATS biosensor screen identifies VEGFR as a regulator of the Hippo pathway in angiogenesis.
Nature communications 03, 2018 | Pubmed ID: 29535383
PI3K Positively Regulates YAP and TAZ in Mammary Tumorigenesis Through Multiple Signaling Pathways.
Molecular cancer research : MCR Jun, 2018 | Pubmed ID: 29545474
The Hippo Pathway: Immunity and Cancer.
Cancers 03, 2018 | Pubmed ID: 29597279
The Hippo pathway and cancer immunity: friend or foe?
Oncoscience 03, 2018 | Pubmed ID: 29854865
TAZ enhances mammary cell proliferation in 3D culture through transcriptional regulation of IRS1.
Cellular signalling Aug, 2018 | Pubmed ID: 30138697