Darren H. Freed

Intermediate-term outcomes of the arterial switch operation for transposition of great arteries in neonates: alive but well?

A whole blood-based perfusate provides superior preservation of myocardial function during ex vivo heart perfusion.

Successful repair of donation after circulatory death lungs with large pulmonary embolus using the lung organ care system for ex vivo thrombolysis and subsequent clinical transplantation.

Donor heart preservation: straight up, or on the rocks?

Basic and Clinical Observations of Mevalonate Depletion on the Mevalonate Signaling Pathway.

Clinical and angiographic outcomes associated with surgical revascularization of angiographically borderline 50-69% coronary artery stenoses.

Inhibition of Viability, Proliferation, Cytokines Secretion, Surface Antigen Expression, and Adipogenic and Osteogenic Differentiation of Adipose-Derived Stem Cells by Seven-Day Exposure to 0.5 T Static Magnetic Fields.

Externally Applied Static Magnetic Field Enhances Cardiac Retention and Functional Benefit of Magnetically Iron-Labeled Adipose-Derived Stem Cells in Infarcted Hearts.

Impact of Reperfusion Calcium and pH on the Resuscitation of Hearts Donated After Circulatory Death.

Functional assessment and transplantation of the donor heart after circulatory death.

A Leukocyte Filter Does Not Provide Further Benefit During Ex Vivo Lung Perfusion.

Preservation of Myocardial Perfusion and Function by Keeping Hypertrophied Heart Empty and Beating for Valve Surgery: An In Vivo MR Study of Pig Hearts.

Extended Bridge to Heart and Lung Transplantation Using Pumpless Extracorporeal Lung Assist.

New Answers to Old Conundrums: What Antibodies, Exosomes and Inflammasomes Bring to the Conversation. Canadian National Transplant Research Program International Summit Report.

Hypoxia enhances the therapeutic potential of superparamagnetic iron oxide-labeled adipose-derived stem cells for myocardial infarction.

Driveline Site Is Not a Predictor of Infection After Ventricular Assist Device Implantation.

Inhibition of pyruvate dehydrogenase kinase improves pulmonary arterial hypertension in genetically susceptible patients.

Negative pressure ventilation decreases inflammation and lung edema during normothermic ex-vivo lung perfusion.

Steroids Limit Myocardial Edema During Ex Vivo Perfusion of Hearts Donated After Circulatory Death.

Corrigendum to "Preservation of Myocardial Perfusion and Function by Keeping Hypertrophied Heart Empty and Beating for Valve Surgery: An In Vivo MR Study of Pig Hearts".

Coronary Artery Bypass Surgery Improves Outcomes in Patients With Diabetes and Left Ventricular Dysfunction.

Transplantation of Hearts Donated after Circulatory Death.

Advanced Dilated Cardiomyopathy in a Patient With Hutterite Limb-Girdle Muscular Dystrophy: Use of a Left Ventricular Assist Device.

Ex situ liver perfusion: Organ preservation into the future.

Normothermic Ex Vivo Machine Perfusion for Liver Grafts Recovered from Donors after Circulatory Death: A Systematic Review and Meta-Analysis.

Ex vivo perfusion induces a time- and perfusate-dependent molecular repair response in explanted porcine lungs.

Preoperative Predictors of Mortality in Short-Term Continuous-Flow Ventricular Assist Devices.

Disparate Remodeling of the Extracellular Matrix and Proteoglycans in Failing Pediatric Versus Adult Hearts.

Enhanced myocardial protection in cardiac donation after circulatory death using Intralipid postconditioning in a porcine model.

Myocardial Functional Decline During Prolonged Ex Situ Heart Perfusion.

Heart Transplantation With Donation After Circulatory Death.

Clearance of transaminases during normothermic ex situ liver perfusion.

Valve-Sparing Aortic Root Replacement 3 Decades After Repair of Aortico-Left Ventricular Tunnel.

Continuous Hemodialysis Does Not Improve Graft Function During Ex Vivo Lung Perfusion Over 24 Hours.

Avoiding initial hypothermia does not improve liver graft quality in a porcine donation after circulatory death (DCD) model of normothermic perfusion.

Total parenteral nutrition in ex vivo lung perfusion: Addressing metabolism improves both inflammation and oxygenation.

Mimicking "J-Shaped" and Anisotropic Stress-Strain Behavior of Human and Porcine Aorta by Fabric-Reinforced Elastomer Composites.

Outcomes following bioprosthetic valve replacement in prior non-cardiac transplant recipients.

Cryopreservation timing is a critical process parameter in a thymic regulatory T-cell therapy manufacturing protocol.

Maintaining the permanence principle for death during in situ normothermic regional perfusion for donation after circulatory death organ recovery: A United Kingdom and Canadian proposal.

Addressing organ shortages: progress in donation after circulatory death for liver transplantation

Current techniques and the future of lung preservation.

The effects of body mass index on outcomes for patients undergoing surgical aortic valve replacement.

Immunity and Stress Responses Are Induced During Ex Situ Heart Perfusion.

A Low-Cost Perfusate Alternative for Ex Vivo Lung Perfusion.

End-Stage Liver Disease Models and Outcomes in Pediatric Patients Supported With Short-Term Continuous-Flow Ventricular Assist Devices.

Discharge and Readmission to the Pediatric Cardiac ICU in Pediatric Patients With Durable Ventricular Assist Devices.

Experimental investigation into the effect of compliance of a mock aorta on cardiac performance.

Structural Valve Deterioration Is Linked to Increased Immune Infiltrate and Chemokine Expression.

The Human Explanted Heart Program: A translational bridge for cardiovascular medicine.

Clinical transplantation using negative pressure ventilation ex situ lung perfusion with extended criteria donor lungs.

Impact of sex on cardiac remodeling and long-term outcomes, following mitral valve replacement.

A review of the immune response stimulated by xenogenic tissue heart valves.

Resveratrol attenuates stimulated T-cell activation and proliferation: potential therapy against cellular rejection in organ transplantation.

Heart donation and transplantation after circulatory determination of death: expert guidance from a Canadian consensus building process.

The Position of the Heart During Normothermic Ex Situ Heart Perfusion is an Important Factor in Preservation and Recovery of Myocardial Function.

Lung Transplantation, Pulmonary Endothelial Inflammation, and Ex-Situ Lung Perfusion: A Review.

Paracorporeal Support in Pediatric Patients: The Role of the Patient-Device Interaction.

The effects of body mass index on long-term outcomes and cardiac remodeling following mitral valve repair surgery.

Sternal Bone Marrow Harvesting and Culturing Techniques from Patients Undergoing Cardiac Surgery.

Chronic exogenous ketone supplementation blunts the decline of cardiac function in the failing heart.

Recellularization of xenograft heart valves reduces the xenoreactive immune response in an in vivo rat model.

Preclinical models of acute liver failure: a comprehensive review.