Professor Shao-tao Tang received his undergraduate and a Ph.D. in Pediatric Surgery from Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. He is currently the director of the Department of Pediatric Surgery, Union Hospital of Tongji Medical College, HUST, Visiting Professor of Cincinnati Children's Hospital and Queen Mary Hospital of Hong Kong University. He is the deputy leader of the Department of Surgical Endoscopy of the Chinese society of Pediatric Surgery and is the member of the standing committee of the Pediatric Surgery Branch of the Chinese Medical Doctor Association. And he is the chairman of Hubei Pediatric Surgery Association and Wuhan Pediatric Surgery Society.
Professor Shao-tao Tang mainly engaged in clinical and basic research on congenital gastrointestinal malformations. He has successfully finished laparoscopic or robotic surgery in more than 1700 Hirschsprung's disease children. He completed the surgical separation of the first case both survival Ischiopagus tetrapus conjoined twins in China, the first case both survival of Thoraco-Omphalopagus twins and the first ex utero intrapartum treatment procedure in Hubei Province. He takes charge of four NSFC (Natural Science Foundation of China), one national key technology and development program of China during the "11th five-year plan", one national health commission industry fund and three natural science foundation of Hubei province.
Professor Shao-tao Tang's scientific interests focusing on the gene genetics of the Hirschsprung's disease and immunological pathogenesis and early diagnosis of biliary atresia. He found the new pathogenic genes NRG3 and ALK of Hirschsprung's disease and the gene polymorphism of NRG1 in the Chinese population. His group found that the new pro-inflammatory cells Th17, inflammatory T-reg cells, and RT cells were involved in the pathogenesis of biliary atresia. The original diagnosis marker MMP7 and the specific HTTS sign of biliary atresia significantly improved the early diagnosis rate.
