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MRC Protein Phosphorylation and Ubiquitylation Unit,
School of Life Sciences,
MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences
Francesca Tonelli has not added Biography.
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The roles of sphingosine kinase 1 and 2 in regulating the metabolome and survival of prostate cancer cells.
Biomolecules Jun, 2013 | Pubmed ID: 24970170
Phosphoproteomics reveals that Parkinson's disease kinase LRRK2 regulates a subset of Rab GTPases.
eLife Jan, 2016 | Pubmed ID: 26824392
Phos-tag analysis of Rab10 phosphorylation by LRRK2: a powerful assay for assessing kinase function and inhibitors.
The Biochemical journal Sep, 2016 | Pubmed ID: 27474410
Systematic proteomic analysis of LRRK2-mediated Rab GTPase phosphorylation establishes a connection to ciliogenesis.
eLife 11, 2017 | Pubmed ID: 29125462
Development of phospho-specific Rab protein antibodies to monitor activity of the LRRK2 Parkinson's disease kinase.
The Biochemical journal 01, 2018 | Pubmed ID: 29127256
Rab29 activation of the Parkinson's disease-associated LRRK2 kinase.
The EMBO journal 01, 2018 | Pubmed ID: 29212815
The Parkinson's disease VPS35[D620N] mutation enhances LRRK2-mediated Rab protein phosphorylation in mouse and human.
The Biochemical journal 06, 2018 | Pubmed ID: 29743203
A pathway for Parkinson's Disease LRRK2 kinase to block primary cilia and Sonic hedgehog signaling in the brain.
eLife 11, 2018 | Pubmed ID: 30398148
A chemical-genetics approach to study the role of atypical Protein Kinase C in .
Development (Cambridge, England) 01, 2019 | Pubmed ID: 30635282
PPM1H phosphatase counteracts LRRK2 signaling by selectively dephosphorylating Rab proteins.
eLife 10, 2019 | Pubmed ID: 31663853
University of Dundee
Ying Fan*,1,
Francesca Tonelli*,1,
Shalini Padmanabhan2,
Marco A.S. Baptista2,
Lindsey Riley2,
Danielle Smith3,
Connie Marras4,
Andrew Howden5,
Dario R. Alessi1,
Esther Sammler1,6
1MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee,
2, The Michael J. Fox Foundation for Parkinson's Research,
3Department of Medical and Molecular Genetics, Indiana University School of Medicine,
4Morton and Gloria Shulman Movement Disorders Centre and the Edmond J. Safra Program in Parkinson's Disease, Toronto Western Hospital, University of Toronto,
5Division of Cell Signalling and Immunology, School of Life Sciences, University of Dundee,
6Division of Molecular and Clinical Medicine, School of Medicine, Ninewells Hospital and Medical School, University of Dundee
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