Tomoki Aoyama

Morphological and biological heterogeneity of three tumorigenic cell lines derived from a single p53-/- osteoblast-like cell line, MMC2.

Clonal heterogeneity in differentiation potential of immortalized human mesenchymal stem cells.

A novel type of EWS-CHOP fusion gene in two cases of myxoid liposarcoma.

Mutation analyses of the NFAT1 gene in chondrosarcomas and enchondromas.

In vitro demonstration of cell-to-cell interaction in growth plate cartilage using chondrocytes established from p53-/- mice.

Expression of the chondromodulin-I gene in chondrosarcomas.

Methylation in the core-promoter region of the chondromodulin-I gene determines the cell-specific expression by regulating the binding of transcriptional activator Sp3.

Mutation analysis of the RECQL4 gene in sporadic osteosarcomas.

PGE2 signal through EP2 promotes the growth of articular chondrocytes.

Disruption of fibroblast growth factor signal pathway inhibits the growth of synovial sarcomas: potential application of signal inhibitors to molecular target therapy.

Polymorphisms of B7 (CD80 and CD86) genes do not affect disease susceptibility to sarcoidosis.

A variant of the SYT-SSX2 fusion gene in a case of synovial sarcoma.

Regeneration of osteonecrosis of canine scapho-lunate using bone marrow stromal cells: possible therapeutic approach for Kienböck disease.

Expression of claudin7 is tightly associated with epithelial structures in synovial sarcomas and regulated by an Ets family transcription factor, ELF3.

In vitro transformation of mesenchymal stem cells by oncogenic H-rasVal12.

Expression of the p16INK4A gene is associated closely with senescence of human mesenchymal stem cells and is potentially silenced by DNA methylation during in vitro expansion.

Cell-specific epigenetic regulation of ChM-I gene expression: crosstalk between DNA methylation and histone acetylation.

Expression of vascular cell adhesion molecule-1 indicates the differentiation potential of human bone marrow stromal cells.

Bilateral phlegmasia dolens associated with Trousseau's syndrome: a case report.

Neuronal differentiation of synovial sarcoma and its therapeutic application.

Inverse correlation of the up-regulation of FZD10 expression and the activation of beta-catenin in synchronous colorectal tumors.

A novel method to isolate mesenchymal stem cells from bone marrow in a closed system using a device made by nonwoven fabric.

Severe erosive arthropathy requiring surgical treatments in systemic lupus erythematosus.

Mesenchymal stem cells cultured under hypoxia escape from senescence via down-regulation of p16 and extracellular signal regulated kinase.

Absence of oncogenic mutations of RAS family genes in soft tissue sarcomas of 100 Japanese patients.

Histone modifiers, YY1 and p300, regulate the expression of cartilage-specific gene, chondromodulin-I, in mesenchymal stem cells.

Trail-walking exercise and fall risk factors in community-dwelling older adults: preliminary results of a randomized controlled trial.

Fallers choose an early transfer gaze strategy during obstacle avoidance in dual-task condition.

Seated stepping exercise in a dual-task condition improves ambulatory function with a secondary task: a randomized controlled trial.

Impact of the O-C2 angle on the oropharyngeal space in normal patients.

Involvement of cancer biomarker C7orf24 in the growth of human osteosarcoma.

Using a Smartphone while walking: a measure of dual-tasking ability as a falls risk assessment tool.

Effects of fear of falling on muscular coactivation during walking.

Effect of resistance training on physical performance and fear of falling in elderly with different levels of physical well-being.

Measurements of stepping accuracy in a multitarget stepping task as a potential indicator of fall risk in elderly individuals.

Rhythmic stepping exercise under cognitive conditions improves fall risk factors in community-dwelling older adults: Preliminary results of a cluster-randomized controlled trial.

Maladaptive turning and gaze behavior induces impaired stepping on multiple footfall targets during gait in older individuals who are at high risk of falling.

Prostaglandin E2 receptor type 2-selective agonist prevents the degeneration of articular cartilage in rabbit knees with traumatic instability.

Faster decline of physical performance in older adults with higher levels of baseline locomotive function.

Effects of a DVD-based seated dual-task stepping exercise on the fall risk factors among community-dwelling elderly adults.

Objective assessment of abnormal gait in patients with rheumatoid arthritis using a smartphone.

Complex obstacle negotiation exercise can prevent falls in community-dwelling elderly Japanese aged 75 years and older.

[Cell therapy for aseptic necrosis of femoral head].

Effects of balance training on muscle coactivation during postural control in older adults: a randomized controlled trial.

Reliability and validity of gait analysis by android-based smartphone.

Community-based exercise program is cost-effective by preventing care and disability in Japanese frail older adults.

Low-intensity pulsed ultrasound inhibits messenger RNA expression of matrix metalloproteinase-13 induced by interleukin-1β in chondrocytes in an intensity-dependent manner.

Global brain atrophy is associated with physical performance and the risk of falls in older adults with cognitive impairment.

Relationship between depression and risk of malnutrition among community-dwelling young-old and old-old elderly people.

The transcription factor Sp3 regulates the expression of a metastasis-related marker of sarcoma, actin filament-associated protein 1-like 1 (AFAP1L1).

Genetically matched human iPS cells reveal that propensity for cartilage and bone differentiation differs with clones, not cell type of origin.

Reduction of atlantoaxial subluxation causes airway stenosis.

Effects of exercise level on biomarkers in a rat knee model of osteoarthritis.

Chronic kidney disease (CKD) is an independent risk factor for long-term care insurance (LTCI) need certification among older Japanese adults: a two-year prospective cohort study.

Development of measurement system for task oriented step tracking using laser range finder.

A novel infrared laser device that measures multilateral parameters of stepping performance for assessment of fall risk in elderly individuals [corrected].

Multitarget stepping program in combination with a standardized multicomponent exercise program can prevent falls in community-dwelling older adults: a randomized, controlled trial.

Arterial stiffness determined according to the cardio-ankle vascular index(CAVI) is associated with mild cognitive decline in community-dwelling elderly subjects.

Prevalence of sarcopenia in community-dwelling Japanese older adults.

Cognitive decline predicts long-term care insurance requirement certification in community-dwelling older Japanese adults: a prospective cohort study.

Self-assessment tool of disease activity of rheumatoid arthritis by using a smartphone application.

A survey examining the correlations between Japanese little league baseball coaches' knowledge of and compliance with pitch count recommendations and player elbow pain.

Age-dependent changes in skeletal muscle mass and visceral fat area in Japanese adults from 40 to 79 years-of-age.

Optimum temperature for extracellular matrix production by articular chondrocytes.

Effect of a Kinect-based exercise game on improving executive cognitive performance in community-dwelling elderly: case control study.

An exploratory clinical trial for idiopathic osteonecrosis of femoral head by cultured autologous multipotent mesenchymal stromal cells augmented with vascularized bone grafts.

Effect of physical activity on memory function in older adults with mild Alzheimer's disease and mild cognitive impairment.

Immature articular cartilage and subchondral bone covered by menisci are potentially susceptive to mechanical load.

Evaluation of reference genes for human chondrocytes cultured in several different thermal environments.

Destabilization of the medial meniscus leads to subchondral bone defects and site-specific cartilage degeneration in an experimental rat model.

Quantification of changes in gait characteristics associated with intermittent claudication in patients with lumbar spinal stenosis.

The physiological characteristics of community-dwelling elderly Japanese with airflow limitation: a cross-sectional study.

Contributions of biarticular myogenic components to the limitation of the range of motion after immobilization of rat knee joint.

Regional comparisons of porcine menisci.

Differential association of frailty with cognitive decline and sarcopenia in community-dwelling older adults.

Rehabilitation program after mesenchymal stromal cell transplantation augmented by vascularized bone grafts for idiopathic osteonecrosis of the femoral head: a preliminary study.

Culture temperature affects redifferentiation and cartilaginous extracellular matrix formation in dedifferentiated human chondrocytes.

Arterial Stiffness Predicts Cognitive Decline in Japanese Community-dwelling Elderly Subjects: A One-year Follow-up Study.

Factors associating with shuttle walking test results in community-dwelling elderly people.

Discordance in recovery between altered locomotion and muscle atrophy induced by simulated microgravity in rats.

Effects of the thermal environment on articular chondrocyte metabolism: a fundamental study to facilitate establishment of an effective thermotherapy for osteoarthritis.

Intermittent application of hypergravity by centrifugation attenuates disruption of rat gait induced by 2 weeks of simulated microgravity.

Functional Movement Screen for Predicting Running Injuries in 18- to 24-Year-Old Competitive Male Runners.

Mail-Based Intervention for Sarcopenia Prevention Increased Anabolic Hormone and Skeletal Muscle Mass in Community-Dwelling Japanese Older Adults: The INE (Intervention by Nutrition and Exercise) Study.

Effects of short-term gentle treadmill walking on subchondral bone in a rat model of instability-induced osteoarthritis.

Alteration of cartilage surface collagen fibers differs locally after immobilization of knee joints in rats.

The association between plantar heel pain and running surfaces in competitive long-distance male runners.

Gait measurement system for the multi-target stepping task using a laser range sensor.

Culture temperature affects human chondrocyte messenger RNA expression in monolayer and pellet culture systems.

Clinical Phenotype Classifications Based on Static Varus Alignment and Varus Thrust in Japanese Patients With Medial Knee Osteoarthritis.

Association of Varus Thrust With Pain and Stiffness and Activities of Daily Living in Patients With Medial Knee Osteoarthritis.

Spatial Change of Cruciate Ligaments in Rat Embryo Knee Joint by Three-Dimensional Reconstruction.

A 12-Week Physical and Cognitive Exercise Program Can Improve Cognitive Function and Neural Efficiency in Community-Dwelling Older Adults: A Randomized Controlled Trial.

Concept Software Based on Kinect for Assessing Dual-Task Ability of Elderly People.

Efficacy of an Exercise Game Based on Kinect in Improving Physical Performances of Fall Risk Factors in Community-Dwelling Older Adults.

The effects of short-term hypoxia on human mesenchymal stem cell proliferation, viability and p16(INK4A) mRNA expression: Investigation using a simple hypoxic culture system with a deoxidizing agent.

Clinical Impact of Coexisting Patellofemoral Osteoarthritis in Japanese Patients With Medial Knee Osteoarthritis.

Subchondral plate porosity colocalizes with the point of mechanical load during ambulation in a rat knee model of post-traumatic osteoarthritis.

A Preseason Checklist for Predicting Elbow Injury in Little League Baseball Players.

Effect of microfabricated microgroove-surface devices on the morphology of mesenchymal stem cells.

Children with flat feet have weaker toe grip strength than those having a normal arch.

Cognitive impairment is associated with the absence of fear of falling in community-dwelling frail older adults.

Exercise intervention increases expression of bone morphogenetic proteins and prevents the progression of cartilage-subchondral bone lesions in a post-traumatic rat knee model.

Sarcopenia as a Risk Factor for Cognitive Deterioration in Community-Dwelling Older Adults: A 1-Year Prospective Study.

The Effect of Exercise on the Early Stages of Mesenchymal Stromal Cell-Induced Cartilage Repair in a Rat Osteochondral Defect Model.

Remobilization causes site-specific cyst formation in immobilization-induced knee cartilage degeneration in an immobilized rat model.

Knee pain during activities of daily living and its relationship with physical activity in patients with early and severe knee osteoarthritis.

Reply to the Letter to the Editor by Mori et al.

Association between comprehensive health literacy and frailty level in community-dwelling older adults: A cross-sectional study in Japan.

Effect of Low-Intensity Pulsed Ultrasound after Mesenchymal Stromal Cell Injection to Treat Osteochondral Defects: An In Vivo Study.

Plasma brain natriuretic peptide level in older outpatients with heart failure is associated with physical frailty, especially with the slowness domain.

Association between floating toe and toe grip strength in school age children: a cross-sectional study.

Plasma microRNAs Are Potential Biomarkers of Acute Rejection After Hindlimb Transplantation in Rats.

Recipient bone marrow-derived stromal cells prolong graft survival in a rat hind limb allotransplantation model.

Physiological exercise loading suppresses post-traumatic osteoarthritis progression via an increase in bone morphogenetic proteins expression in an experimental rat knee model.

Relationship Between Pedometer-Based Physical Activity and Physical Function in Patients With Osteoarthritis of the Knee: A Cross-Sectional Study.

Effect of Capacitive and Resistive electric transfer on haemoglobin saturation and tissue temperature.

The efficacy of a scaffold-free Bio 3D conduit developed from human fibroblasts on peripheral nerve regeneration in a rat sciatic nerve model.

Generating linear regression model to predict motor functions by use of laser range finder during TUG.

Coexisting lateral tibiofemoral osteoarthritis is associated with worse knee pain in patients with mild medial osteoarthritis.

A clinical trial for Kienböck disease by cultured autologous multipotent mesenchymal stromal cells augmented with vascularized bone grafts: A report of five cases.

Preoperative gluteus medius muscle atrophy as a predictor of walking ability after total hip arthroplasty.

Changes in clinical symptoms and functional disability in patients with coexisting patellofemoral and tibiofemoral osteoarthritis: a 1-year prospective cohort study.

Association of bilateral flat feet with knee pain and disability in patients with knee osteoarthritis: A cross-sectional study.

Cartilage formation in the pelvic skeleton during the embryonic and early-fetal period.

Repeatability and agreement of ultrasonography with computed tomography for evaluating forefoot structure in the coronal plane.

Pathohistological investigation of osteochondral tissue obtained during total knee arthroplasty after osteochondral autologous transfer: a case report.

Association of frontal plane knee alignment with foot posture in patients with medial knee osteoarthritis.

Subjective cognitive decline and fall risk in community-dwelling older adults with or without objective cognitive decline.

Interdependence of physical inactivity, loss of muscle mass and low dietary intake: Extrapulmonary manifestations in older chronic obstructive pulmonary disease patients.

Association between mild cognitive impairment and trajectory-based spatial parameters during timed up and go test using a laser range sensor.

MicroRNAs are potential objective and early biomarkers for acute rejection of transplanted limbs in a rat model.

Association of varus thrust with prevalent patellofemoral osteoarthritis: A cross-sectional study.

Association of low back pain with muscle stiffness and muscle mass of the lumbar back muscles, and sagittal spinal alignment in young and middle-aged medical workers.

Low back pain and causative movements in pregnancy: a prospective cohort study.

Varus thrust visualized during gait was associated with inverted foot in patients with knee osteoarthritis: An exploratory study.

Relationship between agility and lower limb muscle strength, targeting university badminton players.

Biomechanical characteristics of stair ambulation in patients with knee OA: A systematic review with meta-analysis toward a better definition of clinical hallmarks.

Comparison of the effects of kilohertz- and low-frequency electric stimulations: A systematic review with meta-analysis.

Relationship between transverse arch height and foot muscles evaluated by ultrasound imaging device.

Psychological health is associated with knee pain and physical function in patients with knee osteoarthritis: an exploratory cross-sectional study.

Inverted Rearfoot posture in subjects with coexisting patellofemoral osteoarthritis in medial knee osteoarthritis: an exploratory study.

Effect of Capacitive and Resistive electric transfer on changes in muscle flexibility and lumbopelvic alignment after fatiguing exercise.

The Association of Variations in Hip and Pelvic Geometry With Pregnancy-Related Sacroiliac Joint Pain Based on a Longitudinal Analysis.

Interaction between low back pain and knee pain contributes to disability level in individuals with knee osteoarthritis: a cross-sectional study.

Ultrasound Parameters for Human Osteoarthritic Subchondral Bone ex Vivo: Comparison with Micro-Computed Tomography Parameters.

Development of a questionnaire survey to evaluate lower limb function of patients with knee osteoarthritis.

Forefoot transverse arch height asymmetry is associated with foot injuries in athletes participating in college track events.

Home exercise therapy to improve muscle strength and joint flexibility effectively treats pre-radiographic knee OA in community-dwelling elderly: a randomized controlled trial.

Three-dimensional motion analysis for comprehensive understanding of gait characteristics after sciatic nerve lesion in rodents.

Effectiveness of mesenchymal stem cells for treating patients with knee osteoarthritis: a meta-analysis toward the establishment of effective regenerative rehabilitation.

Immediate Effects of Transcutaneous Electrical Nerve Stimulation on Pain and Physical Performance in Individuals With Preradiographic Knee Osteoarthritis: A Randomized Controlled Trial.

Trunk movement asymmetry associated with pain, disability, and quadriceps strength asymmetry in individuals with knee osteoarthritis: a cross-sectional study.

Functional evaluation outcomes correlate with histomorphometric changes in the rat sciatic nerve crush injury model: A comparison between sciatic functional index and kinematic analysis.

Relative antigenicity of components in vascularized composite allotransplants: An experimental study of microRNAs expression in rat hind limb transplantation model.

Gait analysis of pregnant patients with lumbopelvic pain using inertial sensor.

Concurrent validity and measurement error of stair climb test in people with pre-radiographic to mild knee osteoarthritis.

Periodic mild heat stimuli diminish extracellular matrix synthesis in pellet cultured human chondrocytes.

Acute effects of capacitive and resistive electric transfer (CRet) on the Achilles tendon.

Effects of interaction between varus thrust and ambulatory physical activity on knee pain in individuals with knee osteoarthritis: an exploratory study with 12-month follow-up.

Relationship between forefoot structure, including the transverse arch, and forefoot pain in patients with hallux valgus.

Proximal gait adaptations in individuals with knee osteoarthritis: A systematic review and meta-analysis.

Patients with early-stage knee osteoarthritis and knee pain have decreased hip abductor muscle strength while descending stairs.

Association of low back pain with presenteeism in hospital nursing staff.

Association Between the Functional Movement Screen Scores and Injuries in Male College Basketball Players.

Quadriceps Weakness in Individuals with Coexisting Medial and Lateral Osteoarthritis.

The Efficacy of a Scaffold-free Bio 3D Conduit Developed from Autologous Dermal Fibroblasts on Peripheral Nerve Regeneration in a Canine Ulnar Nerve Injury Model: A Preclinical Proof-of-Concept Study.

Stair climbing ability in patients with early knee osteoarthritis: Defining the clinical hallmarks of early disease.

Two-Year Weight Loss but Not Body Mass Index Predicts Mortality and Disability in an Older Japanese Community-Dwelling Population.

Therapeutic effects of combined cell transplantation and locomotor training in rats with brain injury.

Relationship between varus thrust during gait and low back pain in people with knee osteoarthritis.

Pervasive game design to evaluate social interaction effects on levels of physical activity among older adults.

Effects of Social Interaction Mechanics in Pervasive Games on the Physical Activity Levels of Older Adults: Quasi-Experimental Study.

The effects of pelvic belt use on pelvic alignment during and after pregnancy: a prospective longitudinal cohort study.

Morphogenesis of the femur at different stages of normal human development.

Induced pluripotent stem cell-derived mesenchymal stem cells prolong hind limb survival in a rat vascularized composite allotransplantation model.

Pelvic alignment changes during the perinatal period.

A scaffold-free Bio 3D nerve conduit for repair of a 10-mm peripheral nerve defect in the rats.

Risk factors of low back pain and the relationship with sagittal vertebral alignment in Tanzania.

Pain catastrophizing affects stair climbing ability in individuals with knee osteoarthritis.

Low Back Pain as a Risk Factor for Recurrent Falls in People with Knee Osteoarthritis.

Detailed analysis of the transverse arch of hallux valgus feet with and without pain using weightbearing ultrasound imaging and precise force sensors.

Hip abductor muscle weakness and slowed turning motion in people with knee osteoarthritis.

Taking the Next Steps in Regenerative Rehabilitation: Establishment of a New Interdisciplinary Field.

Contralateral Limb Effect on Gait Asymmetry and Ipsilateral Pain in a Patient with Knee Osteoarthritis: A Proof-of-Concept Case Report.

Effects of deep thermotherapy on chest wall mobility of healthy elderly women.

Transcutaneous Electrical Nerve Stimulation Improves Stair Climbing Capacity in People with Knee Osteoarthritis.

Regenerative Rehabilitation for Stroke Recovery by Inducing Synergistic Effects of Cell Therapy and Neurorehabilitation on Motor Function: A Narrative Review of Pre-Clinical Studies.

The shape of the transverse arch in high heels while standing.

Ultrasound therapy with optimal intensity facilitates peripheral nerve regeneration in rats through suppression of pro-inflammatory and nerve growth inhibitor gene expression.

Immediate effect of neuromuscular electrical stimulation on the abductor hallucis muscle: A randomized controlled trial.

Pro-angiogenic scaffold-free Bio three-dimensional conduit developed from human induced pluripotent stem cell-derived mesenchymal stem cells promotes peripheral nerve regeneration.

Effects of in vivo cyclic compressive loading on the distribution of local Col2 and superficial lubricin in rat knee cartilage.

Bio 3D Conduits Derived from Bone Marrow Stromal Cells Promote Peripheral Nerve Regeneration.

Mechanism of Peripheral Nerve Regeneration Using a Bio 3D Conduit Derived from Normal Human Dermal Fibroblasts.

Association between hip extensor muscle weakness and disability of activities of daily living in patients with early-stage knee osteoarthritis.

The effect of Capacitive and Resistive electric transfer on non-specific chronic low back pain.

A VCP modulator, KUS121, as a promising therapeutic agent for post-traumatic osteoarthritis.

Promoting Physical Activity in Japanese Older Adults Using a Social Pervasive Game: Randomized Controlled Trial.

Perception Gap in Health-Related Quality of Life Between Young Adult Survivors of Childhood Cancer and Their Family.

Low-Intensity Pulsed Ultrasound Prompts Both Functional and Histologic Improvements While Upregulating the Brain-Derived Neurotrophic Factor Expression after Sciatic Crush Injury in Rats.

Author Correction: A VCP modulator, KUS121, as a promising therapeutic agent for post-traumatic osteoarthritis.

Effect of home-based rehabilitation of purposeful activity-based electrical stimulation therapy for chronic stroke survivors: a crossover randomized controlled trial.

Interfacial polarization of in vivo rat sciatic nerve with crush injury studied via broadband dielectric spectroscopy.

Long-Term Outcome of Sciatic Nerve Regeneration Using Bio3D Conduit Fabricated from Human Fibroblasts in a Rat Sciatic Nerve Model.

Footsteps and walking trajectories during the Timed Up and Go test in young, older, and Parkinson's disease subjects.

Differential Contribution of the Medial and the Lateral Side of the Joint to Symptoms in Knee Osteoarthritis: A Radiographic and Laboratory Analysis in the Nagahama Study.

Ten-year results of mesenchymal stromal cell transplantation augmented with vascularised bone grafts for advanced osteonecrosis of the femoral head.

Health effects of immediate telework introduction during the COVID-19 era in Japan: A cross-sectional study.

Satisfaction With Web-Based Healthcare Content in Cancer Survivors: A Cross-Sectional Survey.

Increased recurrent falls experience in older adults with coexisting of sarcopenia and knee osteoarthritis: a cross-sectional study.

The effect of Liquid ice after high-intensity exercise on muscle function compared to Block ice.

Rate of force development in the quadriceps of individuals with severe knee osteoarthritis: A preliminary cross-sectional study.

Effect of a Rehabilitation Program After Mesenchymal Stromal Cell Transplantation for Advanced Osteonecrosis of the Femoral Head: A 10-Year Follow-Up Study.

Functional manifestations of early knee osteoarthritis: a systematic review and meta-analysis.

Public Opinion and Sentiment Before and at the Beginning of COVID-19 Vaccinations in Japan: Twitter Analysis.

Quantitative computed tomography-based evaluation of skeletal muscle and presence of sarcopenia in patients with chronic obstructive pulmonary disease.

The Effect of Fear of Infection and Sufficient Vaccine Reservation Information on Rapid COVID-19 Vaccination in Japan: Evidence From a Retrospective Twitter Analysis.

The influence of interest in tasks on the autonomic nervous system.

Correction to: Functional manifestations of early knee osteoarthritis: a systematic review and meta-analysis.

A first view of the effect of a trial of early mobilization on the muscle strength and activities of daily living in mechanically ventilated patients with COVID-19.