Kai-Chun Chang is a postdoctoral researcher in Dr. Adam Abate’s lab in Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco. He received a bachelor degree in Life Science with Dean’s award from National Taiwan University. After graduation, he stayed in NTU to continue his pursuit of a Ph.D. degree in Institute of Molecular and Cellular Biology.
During Dr. Chang’s Ph.D. research in Dr. Jin-Der Wen’s lab, he built a single-molecule fluorescence platform and various computational tools to study and model biological macromolecules in translational regulation. With single-molecule resolution, his work uncovers critical conformational intermediates in programmed ribosomal frameshifting. After obtaining his Ph.D. degree, he joined Dr. Abate’s lab as a postdoctoral researcher and received a fellowship from Ministry of Science and Technology, Taiwan. His current research focus is multi-omics analysis of single cells with droplet microfluidics. By applying printed droplet microfluidics (PDM), he connects various omics platforms, including optical observation, mass spec and RNA-seq on single cells. The novel workflow enables high-throughput profiling of single mammalian cells and parallel screening of metabolically engineered yeast strains.
