Department of Nephrology
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Urokinase-induced activation of the gp130/Tyk2/Stat3 pathway mediates a pro-inflammatory effect in human mesangial cells via expression of the anaphylatoxin C5a receptor.
Journal of cell science Jun, 2005 | Pubmed ID: 15944400
The continuous erythropoietin receptor activator affects different pathways of diabetic renal injury.
Journal of the American Society of Nephrology : JASN Jul, 2007 | Pubmed ID: 17554150
Urokinase induces survival or pro-apoptotic signals in human mesangial cells depending on the apoptotic stimulus.
The Biochemical journal Oct, 2008 | Pubmed ID: 18564064
Complement 5a receptor inhibition improves renal allograft survival.
Journal of the American Society of Nephrology : JASN Dec, 2008 | Pubmed ID: 18753257
Erythropoietin prevents diabetes-induced podocyte damage.
Kidney & blood pressure research , 2008 | Pubmed ID: 19096223
Podocytic PKC-alpha is regulated in murine and human diabetes and mediates nephrin endocytosis.
PloS one Apr, 2010 | Pubmed ID: 20419132
Urokinase receptor mediates mobilization, migration, and differentiation of mesenchymal stem cells.
Cardiovascular research Apr, 2011 | Pubmed ID: 21088115
Acute administration of recombinant Angiopoietin-1 ameliorates multiple-organ dysfunction syndrome and improves survival in murine sepsis.
Cytokine Aug, 2011 | Pubmed ID: 21531574
The synthetic tie2 agonist peptide vasculotide protects against vascular leakage and reduces mortality in murine abdominal sepsis.
Critical care (London, England) , 2011 | Pubmed ID: 22040774
Protein kinase C-θ is required for murine neutrophil recruitment and adhesion strengthening under flow.
Journal of immunology (Baltimore, Md. : 1950) Apr, 2012 | Pubmed ID: 22403440
Autoimmunity in CD73/Ecto-5'-nucleotidase deficient mice induces renal injury.
PloS one , 2012 | Pubmed ID: 22666342
Dual inhibition of classical protein kinase C-α and protein kinase C-β isoforms protects against experimental murine diabetic nephropathy.
Diabetes Apr, 2013 | Pubmed ID: 23434935
Renal PKC-ε deficiency attenuates acute kidney injury and ischemic allograft injury via TNF-α-dependent inhibition of apoptosis and inflammation.
American journal of physiology. Renal physiology Sep, 2014 | Pubmed ID: 25056349
A novel therapy to attenuate acute kidney injury and ischemic allograft damage after allogenic kidney transplantation in mice.
PloS one , 2015 | Pubmed ID: 25617900
Food Polyphenols Fail to Cause a Biologically Relevant Reduction of COX-2 Activity.
PloS one , 2015 | Pubmed ID: 26440517
Characterization of changes in plasma and tissue oxylipin levels in LPS and CLP induced murine sepsis.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] Feb, 2016 | Pubmed ID: 26645911
Antagonism of profibrotic microRNA-21 improves outcome of murine chronic renal allograft dysfunction.
Kidney international 09, 2017 | Pubmed ID: 28396121
Protein kinase C beta deficiency increases glucose-mediated peritoneal damage via M1 macrophage polarization and up-regulation of mesothelial protein kinase C alpha.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 06, 2019 | Pubmed ID: 30247663
CX3CL1-CX3CR1 interaction mediates macrophage-mesothelial cross talk and promotes peritoneal fibrosis.
Kidney international 06, 2019 | Pubmed ID: 30948201
The Role of TTP Phosphorylation in the Regulation of Inflammatory Cytokine Production by MK2/3.
Journal of immunology (Baltimore, Md. : 1950) 10, 2019 | Pubmed ID: 31527197
Heparanase-2 protects from LPS-mediated endothelial injury by inhibiting TLR4 signalling.
Scientific reports 09, 2019 | Pubmed ID: 31537875
Labile Heme Aggravates Renal Inflammation and Complement Activation After Ischemia Reperfusion Injury.
Frontiers in immunology , 2019 | Pubmed ID: 31921212
Calcium dobesilate reduces VEGF signaling by interfering with heparan sulfate binding site and protects from vascular complications in diabetic mice.
PloS one , 2020 | Pubmed ID: 31935212
Peritoneal dialysate-range hypertonic glucose promotes T-cell IL-17 production that induces mesothelial inflammation.
European journal of immunology 02, 2021 | Pubmed ID: 32926407
Pre-ischemic renal lavage protects against renal ischemia-reperfusion injury by attenuation of local and systemic inflammatory responses.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 12, 2020 | Pubmed ID: 33089923
SGLT2 Inhibition by Intraperitoneal Dapagliflozin Mitigates Peritoneal Fibrosis and Ultrafiltration Failure in a Mouse Model of Chronic Peritoneal Exposure to High-Glucose Dialysate.
Biomolecules 11, 2020 | Pubmed ID: 33228017
TLR4 Response to LPS Is Reinforced by Urokinase Receptor.
Frontiers in immunology , 2020 | Pubmed ID: 33362762
Author Correction: Heparanase-2 protects from LPS-mediated endothelial injury by inhibiting TLR4 signalling.
Scientific reports Jul, 2021 | Pubmed ID: 34215771
C-X3-C motif chemokine ligand 1/receptor 1 regulates the M1 polarization and chemotaxis of macrophages after hypoxia/reoxygenation injury.
Chronic diseases and translational medicine Dec, 2021 | Pubmed ID: 34786544
Pre-transplant Transcriptional Signature in Peripheral Blood Mononuclear Cells of Acute Renal Allograft Rejection.
Frontiers in medicine , 2021 | Pubmed ID: 35071278
SLAMF8 Participates in Acute Renal Transplant Rejection TLR4 Pathway on Pro-Inflammatory Macrophages.
Frontiers in immunology , 2022 | Pubmed ID: 35432371
A Single Oral Dose of Diclofenac Causes Transition of Experimental Subclinical Acute Kidney Injury to Chronic Kidney Disease.
Biomedicines May, 2022 | Pubmed ID: 35625934
Decheng Yin*,1,2,
Jian Fu*,1,3,
Rongjun Chen4,
Nelli Shushakova5,
Ida Allabauer1,
Xin-Yi Wei1,
Mario Schiffer6,
Diana Dudziak7,
Song Rong*,5,
André Hoerning*,1
1Department of Pediatric and Adolescent Medicine, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nürnberg,
2Department of Pediatric Surgery, Chengdu Women’s and Children's Central Hospital,
3The Key Laboratory of Hainan Trauma and Disaster Rescue, The first affiliated Hospital of Hainan Medical University,
4Department of Department of Pediatric Kidney, Liver, and Metabolic Diseases, Hannover Medical School,
5Department of Nephrology, Hannover Medical School,
6Department of Nephrology, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nürnberg,
7Department of Dermatology, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nürnberg