Pavel Georgiev

P element-mediated duplications of genomic regions in Drosophila melanogaster.

The su(Hw) insulator can disrupt enhancer-promoter interactions when located more than 20 kilobases away from the Drosophila achaete-scute complex.

TAFII40 protein is encoded by the e(y)1 gene: biological consequences of mutations.

Attachment of HeT-A sequences to chromosomal termini in Drosophila melanogaster may occur by different mechanisms.

The novel transcription factor e(y)2 interacts with TAF(II)40 and potentiates transcription activation on chromatin templates.

Heterochromatin protein 1 is involved in control of telomere elongation in Drosophila melanogaster.

The gypsy insulators flanking yellow enhancers do not form a separate transcriptional domain in Drosophila melanogaster: the enhancers can activate an isolated yellow promoter.

Enhancer of terminal gene conversion, a new mutation in Drosophila melanogaster that induces telomere elongation by gene conversion.

Transvection at the end of the truncated chromosome in Drosophila melanogaster.

An endogenous Su(Hw) insulator separates the yellow gene from the Achaete-scute gene complex in Drosophila.

The Mod(mdg4) component of the Su(Hw) insulator inserted in the P transposon can repress its mobility in Drosophila melanogaster.

Interaction between the GAGA factor and Mod(mdg4) proteins promotes insulator bypass in Drosophila.

Drosophila Su(Hw) insulator can stimulate transcription of a weakened yellow promoter over a distance.

A novel multidomain transcription coactivator SAYP can also repress transcription in heterochromatin.

The Ku protein complex is involved in length regulation of Drosophila telomeres.

The Mcp element from the bithorax complex contains an insulator that is capable of pairwise interactions and can facilitate enhancer-promoter communication.

Drosophila telomeres: the non-telomerase alternative.

Pairing between gypsy insulators facilitates the enhancer action in trans throughout the Drosophila genome.

Handling three regulatory elements in one transgene: combined use of cre-lox, FLP-FRT, and I-Scel recombination systems.

Transposition of Regulatory Elements by P-Element-Mediated Rearrangements in Drosophila melanogaster.

Study of long-distance functional interactions between Su(Hw) insulators that can regulate enhancer-promoter communication in Drosophila melanogaster.

Telomere elongation is under the control of the RNAi-based mechanism in the Drosophila germline.

Two isoforms of Drosophila TRF2 are involved in embryonic development, premeiotic chromatin condensation, and proper differentiation of germ cells of both sexes.

Integrity of the Mod(mdg4)-67.2 BTB domain is critical to insulator function in Drosophila melanogaster.

Study of the functional interaction between Mcp insulators from the Drosophila bithorax complex: effects of insulator pairing on enhancer-promoter communication.

Evolutionarily conserved E(y)2/Sus1 protein is essential for the barrier activity of Su(Hw)-dependent insulators in Drosophila.

Long-distance interactions between regulatory elements are suppressed at the end of a terminally deficient chromosome in Drosophila melanogaster.

Characterization of Drosophila telomeric retroelement TAHRE: transcription, transpositions, and RNAi-based regulation of expression.

New properties of Drosophila fab-7 insulator.

Drosophila gypsy insulator and yellow enhancers regulate activity of yellow promoter through the same regulatory element.

Red flag on the white reporter: a versatile insulator abuts the white gene in Drosophila and is omnipresent in mini-white constructs.

'Insulator bodies' are aggregates of proteins but not of insulators.

Functional interaction between the Fab-7 and Fab-8 boundaries and the upstream promoter region in the Drosophila Abd-B gene.

Enhancer-promoter communication is regulated by insulator pairing in a Drosophila model bigenic locus.

Orientation-dependent interaction between Drosophila insulators is a property of this class of regulatory elements.

Zeste can facilitate long-range enhancer-promoter communication and insulator bypass in Drosophila melanogaster.

Drosophila mini-white model system: new insights into positive position effects and the role of transcriptional terminators and gypsy insulator in transgene shielding.

E(y)2/Sus1 is required for blocking PRE silencing by the Wari insulator in Drosophila melanogaster.

Interaction between a pair of gypsy insulators or between heterologous gypsy and Wari insulators modulates Flp site-specific recombination in Drosophila melanogaster.

Insulators, not Polycomb response elements, are required for long-range interactions between Polycomb targets in Drosophila melanogaster.

Selective interactions of boundaries with upstream region of Abd-B promoter in Drosophila bithorax complex and role of dCTCF in this process.

Drosophila BTB/POZ domains of "ttk group" can form multimers and selectively interact with each other.

Insulators form gene loops by interacting with promoters in Drosophila.

SUMO conjugation is required for the assembly of Drosophila Su(Hw) and Mod(mdg4) into insulator bodies that facilitate insulator complex formation.

Insulator protein Su(Hw) recruits SAGA and Brahma complexes and constitutes part of Origin Recognition Complex-binding sites in the Drosophila genome.

New properties of Drosophila scs and scs' insulators.

Effective blocking of the white enhancer requires cooperation between two main mechanisms suggested for the insulator function.

Chromatin insulators and long-distance interactions in Drosophila.

Making connections: insulators organize eukaryotic chromosomes into independent cis-regulatory networks.

Transcription through enhancers suppresses their activity in Drosophila.

Mechanisms and proteins involved in long-distance interactions.

Highly conserved ENY2/Sus1 protein binds to Drosophila CTCF and is required for barrier activity.

Two new insulator proteins, Pita and ZIPIC, target CP190 to chromatin.

Eukaryotic enhancers: common features, regulation, and participation in diseases.

The boundary paradox in the Bithorax complex.

Functional role of dimerization and CP190 interacting domains of CTCF protein in Drosophila melanogaster.

EAST Organizes Drosophila Insulator Proteins in the Interchromosomal Nuclear Compartment and Modulates CP190 Binding to Chromatin.

Transcriptional read-through is not sufficient to induce an epigenetic switch in the silencing activity of Polycomb response elements.

EAST affects the activity of Su(Hw) insulators by two different mechanisms in Drosophila melanogaster.

Architectural proteins Pita, Zw5,and ZIPIC contain homodimerization domain and support specific long-range interactions in Drosophila.

Transvection in Drosophila: trans-interaction between yellow enhancers and promoter is strongly suppressed by a cis-promoter only in certain genomic regions.

Functional Dissection of the Blocking and Bypass Activities of the Fab-8 Boundary in the Drosophila Bithorax Complex.

Large-scale ATP-independent nucleosome unfolding by a histone chaperone.

Boundaries of loop domains (insulators): Determinants of chromosome form and function in multicellular eukaryotes.

The GAGA factor regulatory network: Identification of GAGA factor associated proteins.

Architectural protein Pita cooperates with dCTCF in organization of functional boundaries in Bithorax complex.

Presenilin-1 Delta E9 Mutant Induces STIM1-Driven Store-Operated Calcium Channel Hyperactivation in Hippocampal Neurons.

Interactions between BTB domain of CP190 and two adjacent regions in Su(Hw) are required for the insulator complex formation.

Multiple interactions are involved in a highly specific association of the Mod(mdg4)-67.2 isoform with the Su(Hw) sites in .

Opbp is a new architectural/insulator protein required for ribosomal gene expression.

Role of Su(Hw) zinc finger 10 and interaction with CP190 and Mod(mdg4) proteins in recruiting the Su(Hw) complex to chromatin sites in Drosophila.

The BEN Domain Protein Insensitive Binds to the Chromatin Boundary To Establish Proper Segmental Identity in .

Conserved sequences in the Drosophila mod(mdg4) intron promote poly(A)-independent transcription termination and trans-splicing.

The bithorax complex iab-7 Polycomb response element has a novel role in the functioning of the Fab-7 chromatin boundary.

Boundaries mediate long-distance interactions between enhancers and promoters in the Drosophila Bithorax complex.

Functional dissection of the developmentally restricted BEN domain chromatin boundary factor Insensitive.

Transcription termination sequences support the expression of transgene product secreted with milk.

The same domain of Su(Hw) is required for enhancer blocking and direct promoter repression.

Removal of extra sequences with I-SceI in combination with CRISPR/Cas9 technique for precise gene editing in Drosophila.

Complete reconstitution of bypass and blocking functions in a minimal artificial insulator from complex.

The simultaneous interaction of MSL2 with CLAMP and DNA provides redundancy in the initiation of dosage compensation in males.

Distinct Elements Confer the Blocking and Bypass Functions of the Bithorax Boundary.

Small Drosophila zinc finger C2H2 protein with an N-terminal zinc finger-associated domain demonstrates the architecture functions.

HIPP1 stabilizes the interaction between CP190 and Su(Hw) in the Drosophila insulator complex.

N-terminal domain of the architectural protein CTCF has similar structural organization and ability to self-association in bilaterian organisms.

The insulator functions of the polydactyl C2H2 zinc finger protein CTCF: Necessity versus sufficiency.

Mechanisms of Enhancer-Promoter Interactions in Higher Eukaryotes.

Mapping of functional elements of the Fab-6 boundary involved in the regulation of the Abd-B hox gene in Drosophila melanogaster.

A Non-stop identity complex (NIC) supervises enterocyte identity and protects from premature aging.

Structural basis of diversity and homodimerization specificity of zinc-finger-associated domains in Drosophila.

Mechanism and functional role of the interaction between CP190 and the architectural protein Pita in Drosophila melanogaster.

Boundaries potentiate polycomb response element-mediated silencing.

Clinical Correlations of Polycomb Repressive Complex 2 in Different Tumor Types.

Drosophila architectural protein CTCF is not essential for fly survival and is able to function independently of CP190.

Redundant enhancers in the iab-5 domain cooperatively activate Abd-B in the A5 and A6 abdominal segments of Drosophila.

Mechanisms of CP190 Interaction with Architectural Proteins in Drosophila Melanogaster.

Dimerization Activity of a Disordered N-Terminal Domain from CLAMP Protein.

Structural insights into highly similar spatial organization of zinc-finger associated domains with a very low sequence similarity.

Comparative interactome analysis of the PRE DNA-binding factors: purification of the Combgap-, Zeste-, Psq-, and Adf1-associated proteins.

Structure of the DNMT3B ADD domain suggests the absence of a DNMT3A-like autoinhibitory mechanism.

BTB domains: A structural view of evolution, multimerization, and protein-protein interactions.

Mechanisms of enhancer-promoter communication and chromosomal architecture in mammals and .