Sharon A. Tooze

Activation of ULK Kinase and Autophagy by GABARAP Trafficking from the Centrosome Is Regulated by WAC and GM130.

TBC1D14 regulates autophagy via the TRAPP complex and ATG9 traffic.

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).

GABARAP activates ULK1 and traffics from the centrosome dependent on Golgi partners WAC and GOLGA2/GM130.

Clec16a is Critical for Autolysosome Function and Purkinje Cell Survival.

Digesting the Expanding Mechanisms of Autophagy.

TBC1D14 and TRAPP - Regulating autophagy through ATG9.

TBC1D14 sets the TRAPP for ATG9.

An siRNA screen for ATG protein depletion reveals the extent of the unconventional functions of the autophagy proteome in virus replication.

Rabs and GAPs in starvation-induced autophagy.

Autophagy Captures the Nobel Prize.

So Long Tom!

Molecular Mechanisms of Autophagy-Part B.

Fundamental mechanisms deliver the Nobel Prize to Ohsumi.

A switch from canonical to noncanonical autophagy shapes B cell responses.

Quantifying Autophagic Structures in Mammalian Cells Using Confocal Microscopy.

ATG4B contains a C-terminal LIR motif important for binding and efficient cleavage of mammalian orthologs of yeast Atg8.

Molecular Pathways Controlling Autophagy in Pancreatic Cancer.

Editorial overview: Celebrating the advances in cell biology from China.

Molecular definitions of autophagy and related processes.

Centriolar Satellites Control GABARAP Ubiquitination and GABARAP-Mediated Autophagy.

Autophagy pathway: Cellular and molecular mechanisms.

Control of GABARAP-mediated autophagy by the Golgi complex, centrosome and centriolar satellites.

Membrane dynamics and organelle biogenesis-lipid pipelines and vesicular carriers.

Centrosome to autophagosome signaling: Specific GABARAP regulation by centriolar satellites.

Vps34 PI 3-kinase inactivation enhances insulin sensitivity through reprogramming of mitochondrial metabolism.

A molecular perspective of mammalian autophagosome biogenesis.

SNAREing an ARP requires a LIR.

mTOR independent alteration in ULK1 Ser758 phosphorylation following chronic LRRK2 kinase inhibition.

Identification and Validation of Novel Autophagy Regulators Using an Endogenous Readout siGENOME Screen.

Autophagy Pathway Mapping to Elucidate the Function of Novel Autophagy Regulators Identified by High-Throughput Screening.

MDH1 and MPP7 Regulate Autophagy in Pancreatic Ductal Adenocarcinoma.

Members of the autophagy class III phosphatidylinositol 3-kinase complex I interact with GABARAP and GABARAPL1 via LIR motifs.

Suppression of autophagy during mitosis via CUL4-RING ubiquitin ligases-mediated WIPI2 polyubiquitination and proteasomal degradation.

ATG9A shapes the forming autophagosome through Arfaptin 2 and phosphatidylinositol 4-kinase IIIβ.

A mutation in the major autophagy gene, WIPI2, associated with global developmental abnormalities.

Molecular determinants regulating selective binding of autophagy adapters and receptors to ATG8 proteins.

Axonal autophagosome maturation defect through failure of ATG9A sorting underpins pathology in AP-4 deficiency syndrome.

ATG9A supplies PtdIns4P to the autophagosome initiation site.

Autophagy, Inflammation, and Metabolism (AIM) Center in its second year.

Expression of WIPI2B counteracts age-related decline in autophagosome biogenesis in neurons.

Twenty years of Traffic.

The Golgi as an Assembly Line to the Autophagosome.

Emerging roles of ATG proteins and membrane lipids in autophagosome formation.

Path to autophagy therapeutics with Beth Levine.

The phosphatidylinositol 3-phosphate-binding protein SNX4 controls ATG9A recycling and autophagy.

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition).

Phosphorylation of the LIR Domain of SCOC Modulates ATG8 Binding Affinity and Specificity.

Membrane supply and remodeling during autophagosome biogenesis.

ATG4: More Than a Protease?

SAMM50 acts with p62 in piecemeal basal- and OXPHOS-induced mitophagy of SAM and MICOS components.

Corrigendum to Phosphorylation of the LIR Domain of SCOC Modulates ATG8 Binding Affinity and Specificity.

Phosphoproteomic identification of ULK substrates reveals VPS15-dependent ULK/VPS34 interplay in the regulation of autophagy.

ATG9A protects the plasma membrane from programmed and incidental permeabilization.

SAMM50 is a receptor for basal piecemeal mitophagy and acts with SQSTM1/p62 in OXPHOS-induced mitophagy.

Autophagy in major human diseases.

The ingenious ULKs: expanding the repertoire of the ULK complex with phosphoproteomics.

Homozygous missense variants cause a congenital disorder of autophagy with neurodevelopmental impairments of variable clinical severity and disease course.

Autophagy coordinates chondrocyte development and early joint formation in zebrafish.

Unraveling membrane properties at the organelle-level with LipidDyn.

ATG9A and ATG2A form a heteromeric complex essential for autophagosome formation.

Loss of NDR1/2 kinases impairs endomembrane trafficking and autophagy leading to neurodegeneration.

Membrane association of the ATG8 conjugation machinery emerges as a key regulatory feature for autophagosome biogenesis.

Autophagosome membrane expansion is mediated by the N-terminus and -membrane association of human ATG8s.