Molecular Cell Biology of Autophagy
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Activation of ULK Kinase and Autophagy by GABARAP Trafficking from the Centrosome Is Regulated by WAC and GM130.
Molecular cell Dec, 2015 | Pubmed ID: 26687599
TBC1D14 regulates autophagy via the TRAPP complex and ATG9 traffic.
The EMBO journal Feb, 2016 | Pubmed ID: 26711178
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
Autophagy Jan, 2016 | Pubmed ID: 26799652
GABARAP activates ULK1 and traffics from the centrosome dependent on Golgi partners WAC and GOLGA2/GM130.
Autophagy May, 2016 | Pubmed ID: 26986052
Clec16a is Critical for Autolysosome Function and Purkinje Cell Survival.
Scientific reports , 2016 | Pubmed ID: 26987296
Digesting the Expanding Mechanisms of Autophagy.
Trends in cell biology Aug, 2016 | Pubmed ID: 27050762
TBC1D14 and TRAPP - Regulating autophagy through ATG9.
Cell cycle (Georgetown, Tex.) Jul, 2016 | Pubmed ID: 27105289
TBC1D14 sets the TRAPP for ATG9.
Autophagy Jul, 2016 | Pubmed ID: 27171758
An siRNA screen for ATG protein depletion reveals the extent of the unconventional functions of the autophagy proteome in virus replication.
The Journal of cell biology Aug, 2016 | Pubmed ID: 27573464
Rabs and GAPs in starvation-induced autophagy.
Small GTPases Oct, 2016 | Pubmed ID: 27669114
Autophagy Captures the Nobel Prize.
Cell Dec, 2016 | Pubmed ID: 27912049
So Long Tom!
Traffic (Copenhagen, Denmark) Jan, 2017 | Pubmed ID: 28008716
Molecular Mechanisms of Autophagy-Part B.
Journal of molecular biology Feb, 2017 | Pubmed ID: 28087262
Fundamental mechanisms deliver the Nobel Prize to Ohsumi.
Traffic (Copenhagen, Denmark) Feb, 2017 | Pubmed ID: 28097732
A switch from canonical to noncanonical autophagy shapes B cell responses.
Science (New York, N.Y.) Feb, 2017 | Pubmed ID: 28183981
Quantifying Autophagic Structures in Mammalian Cells Using Confocal Microscopy.
Methods in enzymology , 2017 | Pubmed ID: 28253957
ATG4B contains a C-terminal LIR motif important for binding and efficient cleavage of mammalian orthologs of yeast Atg8.
Autophagy May, 2017 | Pubmed ID: 28287329
Molecular Pathways Controlling Autophagy in Pancreatic Cancer.
Frontiers in oncology , 2017 | Pubmed ID: 28316954
Editorial overview: Celebrating the advances in cell biology from China.
Traffic (Copenhagen, Denmark) Jun, 2017 | Pubmed ID: 28513089
Molecular definitions of autophagy and related processes.
The EMBO journal Jul, 2017 | Pubmed ID: 28596378
Centriolar Satellites Control GABARAP Ubiquitination and GABARAP-Mediated Autophagy.
Current biology : CB Jul, 2017 | Pubmed ID: 28712572
Autophagy pathway: Cellular and molecular mechanisms.
Autophagy , 2018 | Pubmed ID: 28933638
Control of GABARAP-mediated autophagy by the Golgi complex, centrosome and centriolar satellites.
Biology of the cell Jan, 2018 | Pubmed ID: 28990689
Membrane dynamics and organelle biogenesis-lipid pipelines and vesicular carriers.
BMC biology 10, 2017 | Pubmed ID: 29089042
Centrosome to autophagosome signaling: Specific GABARAP regulation by centriolar satellites.
Autophagy , 2017 | Pubmed ID: 29099272
Vps34 PI 3-kinase inactivation enhances insulin sensitivity through reprogramming of mitochondrial metabolism.
Nature communications Nov, 2017 | Pubmed ID: 29180704
A molecular perspective of mammalian autophagosome biogenesis.
The Journal of biological chemistry Apr, 2018 | Pubmed ID: 29371398
SNAREing an ARP requires a LIR.
The Journal of cell biology Mar, 2018 | Pubmed ID: 29449316
mTOR independent alteration in ULK1 Ser758 phosphorylation following chronic LRRK2 kinase inhibition.
Bioscience reports Apr, 2018 | Pubmed ID: 29563162
Identification and Validation of Novel Autophagy Regulators Using an Endogenous Readout siGENOME Screen.
Methods in molecular biology (Clifton, N.J.) , 2019 | Pubmed ID: 30610710
Autophagy Pathway Mapping to Elucidate the Function of Novel Autophagy Regulators Identified by High-Throughput Screening.
Methods in molecular biology (Clifton, N.J.) , 2019 | Pubmed ID: 30610711
MDH1 and MPP7 Regulate Autophagy in Pancreatic Ductal Adenocarcinoma.
Cancer research Apr, 2019 | Pubmed ID: 30765601
Members of the autophagy class III phosphatidylinositol 3-kinase complex I interact with GABARAP and GABARAPL1 via LIR motifs.
Autophagy Aug, 2019 | Pubmed ID: 30767700
Suppression of autophagy during mitosis via CUL4-RING ubiquitin ligases-mediated WIPI2 polyubiquitination and proteasomal degradation.
Autophagy Nov, 2019 | Pubmed ID: 30898011
ATG9A shapes the forming autophagosome through Arfaptin 2 and phosphatidylinositol 4-kinase IIIβ.
The Journal of cell biology May, 2019 | Pubmed ID: 30917996
A mutation in the major autophagy gene, WIPI2, associated with global developmental abnormalities.
Brain : a journal of neurology May, 2019 | Pubmed ID: 30968111
Molecular determinants regulating selective binding of autophagy adapters and receptors to ATG8 proteins.
Nature communications May, 2019 | Pubmed ID: 31053714
Axonal autophagosome maturation defect through failure of ATG9A sorting underpins pathology in AP-4 deficiency syndrome.
Autophagy Mar, 2020 | Pubmed ID: 31142229
ATG9A supplies PtdIns4P to the autophagosome initiation site.
Autophagy Sep, 2019 | Pubmed ID: 31204568
Autophagy, Inflammation, and Metabolism (AIM) Center in its second year.
Autophagy Oct, 2019 | Pubmed ID: 31234750
Expression of WIPI2B counteracts age-related decline in autophagosome biogenesis in neurons.
eLife Jul, 2019 | Pubmed ID: 31309927
Twenty years of Traffic.
Traffic (Copenhagen, Denmark) Jan, 2020 | Pubmed ID: 31854088
The Golgi as an Assembly Line to the Autophagosome.
Trends in biochemical sciences Jun, 2020 | Pubmed ID: 32307224
Emerging roles of ATG proteins and membrane lipids in autophagosome formation.
Cell discovery , 2020 | Pubmed ID: 32509328
Path to autophagy therapeutics with Beth Levine.
Nature reviews. Molecular cell biology Oct, 2020 | Pubmed ID: 32770126
The phosphatidylinositol 3-phosphate-binding protein SNX4 controls ATG9A recycling and autophagy.
Journal of cell science Feb, 2021 | Pubmed ID: 33468622
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition).
Autophagy Feb, 2021 | Pubmed ID: 33634751
Phosphorylation of the LIR Domain of SCOC Modulates ATG8 Binding Affinity and Specificity.
Journal of molecular biology Jun, 2021 | Pubmed ID: 33845085
Membrane supply and remodeling during autophagosome biogenesis.
Current opinion in cell biology Aug, 2021 | Pubmed ID: 33930785
ATG4: More Than a Protease?
Trends in cell biology Jul, 2021 | Pubmed ID: 33972154
SAMM50 acts with p62 in piecemeal basal- and OXPHOS-induced mitophagy of SAM and MICOS components.
The Journal of cell biology Aug, 2021 | Pubmed ID: 34037656
Corrigendum to Phosphorylation of the LIR Domain of SCOC Modulates ATG8 Binding Affinity and Specificity.
Journal of molecular biology Jul, 2021 | Pubmed ID: 34052024
Phosphoproteomic identification of ULK substrates reveals VPS15-dependent ULK/VPS34 interplay in the regulation of autophagy.
The EMBO journal Jul, 2021 | Pubmed ID: 34121209
ATG9A protects the plasma membrane from programmed and incidental permeabilization.
Nature cell biology Aug, 2021 | Pubmed ID: 34257406
SAMM50 is a receptor for basal piecemeal mitophagy and acts with SQSTM1/p62 in OXPHOS-induced mitophagy.
Autophagy Sep, 2021 | Pubmed ID: 34275433
Autophagy in major human diseases.
The EMBO journal Oct, 2021 | Pubmed ID: 34459017
The ingenious ULKs: expanding the repertoire of the ULK complex with phosphoproteomics.
Autophagy Dec, 2021 | Pubmed ID: 34520329
Homozygous missense variants cause a congenital disorder of autophagy with neurodevelopmental impairments of variable clinical severity and disease course.
Brain communications , 2021 | Pubmed ID: 34557665
Autophagy coordinates chondrocyte development and early joint formation in zebrafish.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Nov, 2021 | Pubmed ID: 34708458
Unraveling membrane properties at the organelle-level with LipidDyn.
Computational and structural biotechnology journal , 2022 | Pubmed ID: 35860415
ATG9A and ATG2A form a heteromeric complex essential for autophagosome formation.
Molecular cell Nov, 2022 | Pubmed ID: 36347259
Loss of NDR1/2 kinases impairs endomembrane trafficking and autophagy leading to neurodegeneration.
Life science alliance Feb, 2023 | Pubmed ID: 36446521
Membrane association of the ATG8 conjugation machinery emerges as a key regulatory feature for autophagosome biogenesis.
FEBS letters Jun, 2023 | Pubmed ID: 37259601
Autophagosome membrane expansion is mediated by the N-terminus and -membrane association of human ATG8s.
eLife Jun, 2023 | Pubmed ID: 37288820
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