CHUQ Research Centre
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Treatment with minocycline after disease onset alters astrocyte reactivity and increases microgliosis in SOD1 mutant mice.
Experimental neurology Mar, 2011 | Pubmed ID: 21168408
Induction of peripherin expression in subsets of brain neurons after lesion injury or cerebral ischemia.
Brain research Aug, 2002 | Pubmed ID: 12137917
Minocycline slows disease progression in a mouse model of amyotrophic lateral sclerosis.
Neurobiology of disease Aug, 2002 | Pubmed ID: 12270689
Differential effects of dihydropyridine calcium channel blockers in kainic acid-induced experimental seizures in rats.
Epilepsy research Jan, 2003 | Pubmed ID: 12536054
Pathways to motor neuron degeneration in transgenic mouse models.
Biochimie Nov, 2002 | Pubmed ID: 12595144
Intra-axonal recording from large sensory myelinated axons: demonstration of impaired membrane conductances in early experimental diabetes.
Diabetologia Feb, 2003 | Pubmed ID: 12627320
Cell cycle regulators in the neuronal death pathway of amyotrophic lateral sclerosis caused by mutant superoxide dismutase 1.
The Journal of neuroscience : the official journal of the Society for Neuroscience Mar, 2003 | Pubmed ID: 12657672
Efficient three-drug cocktail for disease induced by mutant superoxide dismutase.
Annals of neurology Apr, 2003 | Pubmed ID: 12666110
Up-regulation of peripherin is associated with alterations in synaptic plasticity in CA1 and CA3 regions of hippocampus.
Neurobiology of disease Mar, 2005 | Pubmed ID: 15686970
Cytoskeletal defects in amyotrophic lateral sclerosis (motor neuron disease).
Novartis Foundation symposium , 2005 | Pubmed ID: 15773754
Transgenic mouse models of amyotrophic lateral sclerosis.
Biochimica et biophysica acta Nov-Dec, 2006 | Pubmed ID: 16675207
Differential neuroprotective effects of a minocycline-based drug cocktail in transient and permanent focal cerebral ischemia.
Experimental neurology Mar, 2007 | Pubmed ID: 17234187
Selective ablation of proliferating microglial cells exacerbates ischemic injury in the brain.
The Journal of neuroscience : the official journal of the Society for Neuroscience Mar, 2007 | Pubmed ID: 17344397
Real-time imaging of astrocyte response to quantum dots: in vivo screening model system for biocompatibility of nanoparticles.
Nano letters Aug, 2007 | Pubmed ID: 17638392
Inflammation in ischemic brain injury: timing is important.
Critical reviews in neurobiology , 2006 | Pubmed ID: 17725517
Live imaging of neuroinflammation reveals sex and estrogen effects on astrocyte response to ischemic injury.
Stroke; a journal of cerebral circulation Mar, 2008 | Pubmed ID: 18258827
Als2 mRNA splicing variants detected in KO mice rescue severe motor dysfunction phenotype in Als2 knock-down zebrafish.
Human molecular genetics Sep, 2008 | Pubmed ID: 18558633
Chapter 6 Animal models of motor neuron death.
Handbook of clinical neurology / edited by P.J. Vinken and G.W. Bruyn , 2007 | Pubmed ID: 18808891
Live imaging of amyotrophic lateral sclerosis pathogenesis: disease onset is characterized by marked induction of GFAP in Schwann cells.
Glia Aug, 2009 | Pubmed ID: 19115383
Inflammation, plasticity and real-time imaging after cerebral ischemia.
Acta neuropathologica May, 2009 | Pubmed ID: 19225790
Microglial response to gold nanoparticles.
ACS nano May, 2010 | Pubmed ID: 20329742
Lipopolysaccharide-QD micelles induce marked induction of TLR2 and lipid droplet accumulation in olfactory bulb microglia.
Molecular pharmaceutics Aug, 2010 | Pubmed ID: 20459083
Distinct biochemical signatures characterize peripherin isoform expression in both traumatic neuronal injury and motor neuron disease.
Journal of neurochemistry Aug, 2010 | Pubmed ID: 20533992
Involvement of TLR2 in recognition of acute gammaherpesvirus-68 infection.
PloS one , 2010 | Pubmed ID: 21060793
PCSK9 reduces the protein levels of the LDL receptor in mouse brain during development and after ischemic stroke.
Journal of lipid research Jul, 2011 | Pubmed ID: 21518694
Model System for Live Imaging of Neuronal Responses to Injury and Repair.
Molecular imaging Apr, 2011 | Pubmed ID: 21524377
Pathological hallmarks of amyotrophic lateral sclerosis/frontotemporal lobar degeneration in transgenic mice produced with TDP-43 genomic fragments.
Brain : a journal of neurology Sep, 2011 | Pubmed ID: 21752789
Accumulation of dietary docosahexaenoic acid in the brain attenuates acute immune response and development of postischemic neuronal damage.
Stroke; a journal of cerebral circulation Oct, 2011 | Pubmed ID: 21852616
The role of the MYD88-dependent pathway in MPTP-induced brain dopaminergic degeneration.
Journal of neuroinflammation , 2011 | Pubmed ID: 21989292
Deregulation of TDP-43 in amyotrophic lateral sclerosis triggers nuclear factor κB-mediated pathogenic pathways.
The Journal of experimental medicine Nov, 2011 | Pubmed ID: 22084410
Model system for live imaging of neuronal responses to injury and repair.
Molecular imaging Dec, 2011 | Pubmed ID: 22201534
Real-time imaging after cerebral ischemia: model systems for visualization of inflammation and neuronal repair.
Methods in enzymology , 2012 | Pubmed ID: 22341222
Galectin-3 is required for resident microglia activation and proliferation in response to ischemic injury.
The Journal of neuroscience : the official journal of the Society for Neuroscience Jul, 2012 | Pubmed ID: 22836271
Toll-like receptor 2 deficiency leads to delayed exacerbation of ischemic injury.
Journal of neuroinflammation , 2012 | Pubmed ID: 22873409