Matthias Heinig

Institute of Computational Biology, Helmholtz Zentrum München

Affiliated withHelmholtz Zentrum München Technical University of Munich German Centre for Cardiovascular Research (DZHK), partner site Munich Heart Alliance

Research Area

Genetics

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title	2024

Other Publications

Article	Year
Alternative Splicing Signatures in RNA-seq Data: Percent Spliced in (PSI). Current protocols in human genetics\| PubMed ID: 26439713	2015
Meta-analysis identifies seven susceptibility loci involved in the atopic march. Nature communications\| PubMed ID: 26542096	2015
A roadmap of constitutive NF-κB activity in Hodgkin lymphoma: Dominant roles of p50 and p52 revealed by genome-wide analyses. Genome medicine\| PubMed ID: 26988706	2016
Comparison of Cox Model Methods in A Low-dimensional Setting with Few Events. Genomics, proteomics & bioinformatics\| PubMed ID: 27224515	2016
Principles of microRNA Regulation Revealed Through Modeling microRNA Expression Quantitative Trait Loci. Genetics\| PubMed ID: 27260304	2016
52 Genetic Loci Influencing Myocardial Mass. Journal of the American College of Cardiology\| PubMed ID: 27659466	2016
Epigenetics and Control of RNAs. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 27933526	2017
Transcriptome-wide co-expression analysis identifies LRRC2 as a novel mediator of mitochondrial and cardiac function. PloS one\| PubMed ID: 28158196	2017
Regulation of body weight and energy homeostasis by neuronal cell adhesion molecule 1. Nature neuroscience\| PubMed ID: 28628102	2017
Natural genetic variation of the cardiac transcriptome in non-diseased donors and patients with dilated cardiomyopathy. Genome biology\| PubMed ID: 28903782	2017
Cadm2 regulates body weight and energy homeostasis in mice. Molecular metabolism\| PubMed ID: 29217450	2018
Using Gene Expression to Annotate Cardiovascular GWAS Loci. Frontiers in cardiovascular medicine\| PubMed ID: 29922679	2018
Efficient Parameter Estimation Enables the Prediction of Drug Response Using a Mechanistic Pan-Cancer Pathway Model. Cell systems\| PubMed ID: 30503647	2018
Systems Genetics Approaches in Rat Identify Novel Genes and Gene Networks Associated With Cardiac Conduction. Journal of the American Heart Association\| PubMed ID: 30608189	2018
Association of Human Promoter Variants with the Occurrence of Knee-Osteoarthritis in a Case Control Association Study. International journal of molecular sciences\| PubMed ID: 30893847	2019
Inflammatory macrophage memory in nonsteroidal anti-inflammatory drug-exacerbated respiratory disease. The Journal of allergy and clinical immunology\| PubMed ID: 32540397	2021
Identification and characterization of distinct brown adipocyte subtypes in C57BL/6J mice. Life science alliance\| PubMed ID: 33257475	2021
scPower accelerates and optimizes the design of multi-sample single cell transcriptomic studies. Nature communications\| PubMed ID: 34785648	2021
Polygenic risk for coronary artery disease in the Scottish and English population. BMC cardiovascular disorders\| PubMed ID: 34876023	2021
Genetic variation influencing DNA methylation provides insights into molecular mechanisms regulating genomic function. Nature genetics\| PubMed ID: 34980917	2022
Tissue-specific multi-omics analysis of atrial fibrillation. Nature communications\| PubMed ID: 35064145	2022
Pathogenic variants damage cell composition and single cell transcription in cardiomyopathies. Science (New York, N.Y.)\| PubMed ID: 35926050	2022
Probing cell identity hierarchies by fate titration and collision during direct reprogramming. Molecular systems biology\| PubMed ID: 36106915	2022
A proteome-scale map of the SARS-CoV-2-human contactome. Nature biotechnology\| PubMed ID: 36217029	2023
Network reconstruction for trans acting genetic loci using multi-omics data and prior information. Genome medicine\| PubMed ID: 36344995	2022
DeepSom: a CNN-based approach to somatic variant calling in WGS samples without a matched normal. Bioinformatics (Oxford, England)\| PubMed ID: 36637201	2023
Predictive model of transcriptional elongation control identifies trans regulatory factors from chromatin signatures. Nucleic acids research\| PubMed ID: 36727445	2023
Machine learning reveals STAT motifs as predictors for GR-mediated gene repression. Computational and structural biotechnology journal\| PubMed ID: 36879886	2023
Identification of genetic variants that impact gene co-expression relationships using large-scale single-cell data. Genome biology\| PubMed ID: 37072791	2023
Darier's disease exhibits a unique cutaneous microbial dysbiosis associated with inflammation and body malodour. Microbiome\| PubMed ID: 37496039	2023
An arrhythmogenic metabolite in atrial fibrillation. Journal of translational medicine\| PubMed ID: 37620858	2023
Correction: Darier's disease exhibits a unique cutaneous microbial dysbiosis associated with inflammation and body malodour. Microbiome\| PubMed ID: 37705089	2023
Speos: an ensemble graph representation learning framework to predict core gene candidates for complex diseases. Nature communications\| PubMed ID: 37938585	2023
Single-Cell Dissection of the Immune Response After Acute Myocardial Infarction. Circulation. Genomic and precision medicine\| PubMed ID: 38752343	2024
Multiomic analyses uncover immunological signatures in acute and chronic coronary syndromes. Nature medicine\| PubMed ID: 38773340	2024
Plasmacytoid dendritic cells control homeostasis of megakaryopoiesis. Nature\| PubMed ID: 38987596	2024
Differential Analysis of Protein-DNA Binding Using ChIP-Seq Data. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 39141230	2024