Mikala Egeblad

New functions for the matrix metalloproteinases in cancer progression.

Ets2-dependent stromal regulation of mouse mammary tumors.

Evidence that transgenes encoding components of the Wnt signaling pathway preferentially induce mammary cancers from progenitor cells.

Truncation of activated leukocyte cell adhesion molecule: a gateway to melanoma metastasis.

Coevolution of cancer and stromal cellular responses.

Proteolytic cleavage and phosphorylation of a tumor-associated ErbB4 isoform promote ligand-independent survival and cancer cell growth.

Sulf-2, a proangiogenic heparan sulfate endosulfatase, is upregulated in breast cancer.

Type I collagen is a genetic modifier of matrix metalloproteinase 2 in murine skeletal development.

GATA-3 links tumor differentiation and dissemination in a luminal breast cancer model.

Matrix metalloproteinase 13 is induced in fibroblasts in polyomavirus middle T antigen-driven mammary carcinoma without influencing tumor progression.

Visualizing stromal cell dynamics in different tumor microenvironments by spinning disk confocal microscopy.

Matrix crosslinking forces tumor progression by enhancing integrin signaling.

Stromal regulation of vessel stability by MMP14 and TGFbeta.

Tumors as organs: complex tissues that interface with the entire organism.

Dynamic interplay between the collagen scaffold and tumor evolution.

Preparation of mice for long-term intravital imaging of the mammary gland.

Monitoring of vital signs for long-term survival of mice under anesthesia.

Dynamic, long-term in vivo imaging of tumor-stroma interactions in mouse models of breast cancer using spinning-disk confocal microscopy.

Innate immune cells in breast cancer--from villains to heroes?

Marginating dendritic cells of the tumor microenvironment cross-present tumor antigens and stably engage tumor-specific T cells.

Imaging tumor-stroma interactions during chemotherapy reveals contributions of the microenvironment to resistance.

Caught in the act: revealing the metastatic process by live imaging.

System-wide analysis reveals a complex network of tumor-fibroblast interactions involved in tumorigenicity.

Cancer: Sugar-coated cell signalling.

Presence of insulin-like growth factor binding proteins correlates with tumor-promoting effects of matrix metalloproteinase 9 in breast cancer.

Differentiation of mammary tumors and reduction in metastasis upon Malat1 lncRNA loss.

Cancer cells induce metastasis-supporting neutrophil extracellular DNA traps.

EPCR promotes breast cancer progression by altering SPOCK1/testican 1-mediated 3D growth.

Distinct populations of inflammatory fibroblasts and myofibroblasts in pancreatic cancer.

Enhancer Reprogramming Promotes Pancreatic Cancer Metastasis.

Re-cyclin' Cell-Cycle Components to Make NETs.

Bone Talk: Activated Osteoblasts Promote Lung Cancer Growth.

Unresolved endoplasmic reticulum stress engenders immune-resistant, latent pancreatic cancer metastases.

POU2F3 is a master regulator of a tuft cell-like variant of small cell lung cancer.

Neutrophil extracellular traps produced during inflammation awaken dormant cancer cells in mice.

Transcriptomic profiles conducive to immune-mediated tumor rejection in human breast cancer skin metastases treated with Imiquimod.

Tumours pick the path to cancer inflammation.

Stressing Out about Cancer Immunotherapy.

Communication in tiny packages: Exosomes as means of tumor-stroma communication.

The entry of nanoparticles into solid tumours.

A framework for advancing our understanding of cancer-associated fibroblasts.

Targeting potential drivers of COVID-19: Neutrophil extracellular traps.

Squamous trans-differentiation of pancreatic cancer cells promotes stromal inflammation.

Neutrophil extracellular traps in COVID-19.

Nebulized in-line endotracheal dornase alfa and albuterol administered to mechanically ventilated COVID-19 patients: A case series.

Neutrophil extracellular traps contribute to immunothrombosis in COVID-19 acute respiratory distress syndrome.

Cancer cell CCR2 orchestrates suppression of the adaptive immune response.

A fluorogenic cyclic peptide for imaging and quantification of drug-induced apoptosis.

Gut Feelings Block the Flow: Microbiota Links Stress to Vascular Disease.

Nebulized in-line endotracheal dornase alfa and albuterol administered to mechanically ventilated COVID-19 patients: a case series.

Frontiers in cancer immunotherapy-a symposium report.

Patients with COVID-19: in the dark-NETs of neutrophils.

Multi-color Flow Cytometry for Comprehensive Analysis of the Tumor Immune Infiltrate in a Murine Model of Breast Cancer.

Treatment with Granulocyte-colony Stimulating Factor (G-CSF) is not associated with Increased Risk of Brain Metastasis in Patients with Stage IV Breast Cancer.

Activating a collaborative innate-adaptive immune response to control metastasis.

A Bivalent Activatable Fluorescent Probe for Screening and Intravital Imaging of Chemotherapy-Induced Cancer Cell Death.

Innate Immunity and Cancer Pathophysiology.