Center for Systems Biology
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Near-infrared fluorescent probe for imaging of pancreatic beta cells.
Bioconjugate chemistry Jul, 2010 | Pubmed ID: 20583828
Bioorthogonal small-molecule ligands for PARP1 imaging in living cells.
Chembiochem : a European journal of chemical biology Nov, 2010 | Pubmed ID: 20967817
High-Yielding, Two-Step (18)F Labeling Strategy for (18)F-PARP1 Inhibitors.
ChemMedChem Jan, 2011 | Pubmed ID: 21207434
Synthesis and in vivo imaging of a 18F-labeled PARP1 inhibitor using a chemically orthogonal scavenger-assisted high-performance method.
Angewandte Chemie (International ed. in English) Feb, 2011 | Pubmed ID: 21328671
High-yielding, two-step 18F labeling strategy for 18F-PARP1 inhibitors.
ChemMedChem Mar, 2011 | Pubmed ID: 21360818
Towards quantitative catalytic lignin depolymerization.
Chemistry (Weinheim an der Bergstrasse, Germany) May, 2011 | Pubmed ID: 21472799
In vivo PET imaging of histone deacetylases by 18F-suberoylanilide hydroxamic acid (18F-SAHA).
Journal of medicinal chemistry Aug, 2011 | Pubmed ID: 21721525
Accurate measurement of pancreatic islet beta-cell mass using a second-generation fluorescent exendin-4 analog.
Proceedings of the National Academy of Sciences of the United States of America Aug, 2011 | Pubmed ID: 21768367
Bioorthogonal probes for polo-like kinase 1 imaging and quantification.
Angewandte Chemie (International ed. in English) Sep, 2011 | Pubmed ID: 21948435
Nanoparticle-mediated measurement of target-drug binding in cancer cells.
ACS nano Nov, 2011 | Pubmed ID: 21962084
Ubiquitous detection of gram-positive bacteria with bioorthogonal magnetofluorescent nanoparticles.
ACS nano Nov, 2011 | Pubmed ID: 21967150
Specific pathogen detection using bioorthogonal chemistry and diagnostic magnetic resonance.
Bioconjugate chemistry Dec, 2011 | Pubmed ID: 22043803
Imaging therapeutic PARP inhibition in vivo through bioorthogonally developed companion imaging agents.
Neoplasia (New York, N.Y.) Mar, 2012 | Pubmed ID: 22496617
Bioorthogonal imaging of aurora kinase A in live cells.
Angewandte Chemie (International ed. in English) Jul, 2012 | Pubmed ID: 22644700
Microfluidic cell sorter (μFCS) for on-chip capture and analysis of single cells.
Advanced healthcare materials Jul, 2012 | Pubmed ID: 23184773
Single-cell and subcellular pharmacokinetic imaging allows insight into drug action in vivo.
Nature communications , 2013 | Pubmed ID: 23422672
Phenylalanine--a biogenic ligand with flexible η6- and η6:κ1-coordination at ruthenium(II) centres.
Dalton transactions (Cambridge, England : 2003) Jun, 2013 | Pubmed ID: 23632736
A Pretargeted PET Imaging Strategy Based on Bioorthogonal Diels-Alder Click Chemistry.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine Aug, 2013 | Pubmed ID: 23708196
Targeting cathepsin E in pancreatic cancer by a small molecule allows in vivo detection.
Neoplasia (New York, N.Y.) Jul, 2013 | Pubmed ID: 23814481
Efficient (18)F-Labeling of Synthetic Exendin-4 Analogues for Imaging Beta Cells.
ChemistryOpen Aug, 2012 | Pubmed ID: 23997998
(18)F-labeled-bioorthogonal liposomes for in vivo targeting.
Bioconjugate chemistry Nov, 2013 | Pubmed ID: 24180480
The inverse electron demand Diels-Alder click reaction in radiochemistry.
Journal of labelled compounds & radiopharmaceuticals Apr, 2014 | Pubmed ID: 24347429
Metal-conjugated affinity labels: a new concept to create enantioselective artificial metalloenzymes.
ChemistryOpen Apr, 2013 | Pubmed ID: 24551533
Effect of small-molecule modification on single-cell pharmacokinetics of PARP inhibitors.
Molecular cancer therapeutics Apr, 2014 | Pubmed ID: 24552776
Efficient acid-catalyzed (18) F/(19) F fluoride exchange of BODIPY dyes.
ChemMedChem Jul, 2014 | Pubmed ID: 24596307
Building Blocks for the Construction of Bioorthogonally Reactive Peptides via Solid-Phase Peptide Synthesis.
ChemistryOpen Apr, 2014 | Pubmed ID: 24808990
In vivo imaging of GLP-1R with a targeted bimodal PET/fluorescence imaging agent.
Bioconjugate chemistry Jul, 2014 | Pubmed ID: 24856928
Synthesis of the first radiolabeled 188Re N-heterocyclic carbene complex and initial studies on its potential use in radiopharmaceutical applications.
Journal of labelled compounds & radiopharmaceuticals Jun, 2014 | Pubmed ID: 24889257
PARPi-FL--a fluorescent PARP1 inhibitor for glioblastoma imaging.
Neoplasia (New York, N.Y.) May, 2014 | Pubmed ID: 24970386
A modular labeling strategy for in vivo PET and near-infrared fluorescence imaging of nanoparticle tumor targeting.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine Oct, 2014 | Pubmed ID: 25060196
Cerenkov Luminescence Imaging for Radiation Dose Calculation of a ⁹⁰Y-Labeled Gastrin-Releasing Peptide Receptor Antagonist.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine May, 2015 | Pubmed ID: 25840974
Dual-Modality Optical/PET Imaging of PARP1 in Glioblastoma.
Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging Dec, 2015 | Pubmed ID: 25895168
PET Imaging of Tumor-Associated Macrophages with 89Zr-Labeled High-Density Lipoprotein Nanoparticles.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine Aug, 2015 | Pubmed ID: 26112022
Development of a clickable bimodal fluorescent/PET probe for in vivo imaging.
EJNMMI research Dec, 2015 | Pubmed ID: 26285667
Optimization of a Pretargeted Strategy for the PET Imaging of Colorectal Carcinoma via the Modulation of Radioligand Pharmacokinetics.
Molecular pharmaceutics Oct, 2015 | Pubmed ID: 26287993
Inhibiting macrophage proliferation suppresses atherosclerotic plaque inflammation.
Science advances Apr, 2015 | Pubmed ID: 26295063
Radioiodinated PARP1 tracers for glioblastoma imaging.
EJNMMI research Dec, 2015 | Pubmed ID: 26337803
(18)F-Based Pretargeted PET Imaging Based on Bioorthogonal Diels-Alder Click Chemistry.
Bioconjugate chemistry Feb, 2016 | Pubmed ID: 26479967
Non-invasive PET Imaging of PARP1 Expression in Glioblastoma Models.
Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging Jun, 2016 | Pubmed ID: 26493053
Optical Imaging of PARP1 in Response to Radiation in Oral Squamous Cell Carcinoma.
PloS one , 2016 | Pubmed ID: 26808835
Detection and delineation of oral cancer with a PARP1 targeted optical imaging agent.
Scientific reports Feb, 2016 | Pubmed ID: 26900125
In Vivo PET Imaging of HDL in Multiple Atherosclerosis Models.
JACC. Cardiovascular imaging Aug, 2016 | Pubmed ID: 27236528
Nanoreporter PET predicts the efficacy of anti-cancer nanotherapy.
Nature communications Jun, 2016 | Pubmed ID: 27319780
Pretargeted PET Imaging Using a Site-Specifically Labeled Immunoconjugate.
Bioconjugate chemistry Aug, 2016 | Pubmed ID: 27356886
Near-Infrared Intraoperative Chemiluminescence Imaging.
ChemMedChem Sep, 2016 | Pubmed ID: 27471800
Immune cell screening of a nanoparticle library improves atherosclerosis therapy.
Proceedings of the National Academy of Sciences of the United States of America Nov, 2016 | Pubmed ID: 27791119
Imaging-guided revival of nanomedicine?
Nanomedicine (London, England) Jan, 2017 | Pubmed ID: 27876441
A Pretargeted Approach for the Multimodal PET/NIRF Imaging of Colorectal Cancer.
Theranostics , 2016 | Pubmed ID: 27924162
Polyglucose nanoparticles with renal elimination and macrophage avidity facilitate PET imaging in ischaemic heart disease.
Nature communications Jan, 2017 | Pubmed ID: 28091604
Biomarker based PET Imaging of Diffuse Intrinsic Pontine Glioma in Mouse Models.
Cancer research Jan, 2017 | Pubmed ID: 28108511
Evaluation of [(18)F]-ATRi as PET tracer for in vivo imaging of ATR in mouse models of brain cancer.
Nuclear medicine and biology Jan, 2017 | Pubmed ID: 28157626
Development of a New Folate-Derived Ga-68-Based PET Imaging Agent.
Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging Feb, 2017 | Pubmed ID: 28194631
Gabriel E. Büchel1,2,
Brandon Carney1,3,
Jun Tang1,
Brian M. Zeglis1,3,
Jörg Eppinger2,
Thomas Reiner1,4
1Department of Radiology, Memorial Sloan Kettering Cancer Center,
2KAUST Catalysis Center, King Abdullah University of Science and Technology,
3Department of Chemistry, Hunter College, and PhD Program in Chemistry, Graduate Center of City University of New York,
4Department of Radiology, Weill Cornell Medical College