Jean C. Lee

Novel synthetic (poly)glycerolphosphate-based antistaphylococcal conjugate vaccine.

Development of Antistaphylococcal Vaccines.

Regulation of Staphylococcus aureus capsular polysaccharide expression by agr and sarA.

Three highly conserved proteins catalyze the conversion of UDP-N-acetyl-D-glucosamine to precursors for the biosynthesis of O antigen in Pseudomonas aeruginosa O11 and capsule in Staphylococcus aureus type 5. Implications for the UDP-N-acetyl-L-fucosamine biosynthetic pathway.

Primary sequence characterization of catestatin intermediates and peptides defines proteolytic cleavage sites utilized for converting chromogranin a into active catestatin secreted from neuroendocrine chromaffin cells.

Acute tubular necrosis in a patient receiving tenofovir.

Staphylococcus aureus capsular polysaccharides.

Staphylococcus aureus strains that express serotype 5 or serotype 8 capsular polysaccharides differ in virulence.

The pathogenesis of Staphylococcus aureus infection in the diabetic NOD mouse.

Whole-genome sequencing of staphylococcus haemolyticus uncovers the extreme plasticity of its genome and the evolution of human-colonizing staphylococcal species.

Capsule-negative Staphylococcus aureus induces chronic experimental mastitis in mice.

Molecular characterization of the capsule locus from non-typeable Staphylococcus aureus.

Immunization with Staphylococcus aureus clumping factor B, a major determinant in nasal carriage, reduces nasal colonization in a murine model.

CD4+ T cells and CXC chemokines modulate the pathogenesis of Staphylococcus aureus wound infections.

Capsular polysaccharide masks clumping factor A-mediated adherence of Staphylococcus aureus to fibrinogen and platelets.

Structural and biological characterization of a capsular polysaccharide produced by Staphylococcus haemolyticus.

Comparison of virulence in community-associated methicillin-resistant Staphylococcus aureus pulsotypes USA300 and USA400 in a rat model of pneumonia.

IFN-gamma regulated chemokine production determines the outcome of Staphylococcus aureus infection.

Intrafamilial outbreak of subcutaneous abscesses caused by PVL-positive methicillin-sensitive Staphylococcus aureus.

NorB, an efflux pump in Staphylococcus aureus strain MW2, contributes to bacterial fitness in abscesses.

Vaccination and passive immunisation against Staphylococcus aureus.

Antibodies to capsular polysaccharide and clumping factor A prevent mastitis and the emergence of unencapsulated and small-colony variants of Staphylococcus aureus in mice.

Defects in innate immunity predispose C57BL/6J-Leprdb/Leprdb mice to infection by Staphylococcus aureus.

Staphylococcal vaccines and immunotherapies.

Proteolytic fragments of chromogranins A and B represent major soluble components of chromaffin granules, illustrated by two-dimensional proteomics with NH(2)-terminal Edman peptide sequencing and MALDI-TOF MS.

The effectiveness of the controlled release of gentamicin from polyelectrolyte multilayers in the treatment of Staphylococcus aureus infection in a rabbit bone model.

Characterization of the structure and biological functions of a capsular polysaccharide produced by Staphylococcus saprophyticus.

Animal and human antibodies to distinct Staphylococcus aureus antigens mutually neutralize opsonic killing and protection in mice.

The zwitterionic cell wall teichoic acid of Staphylococcus aureus provokes skin abscesses in mice by a novel CD4+ T-cell-dependent mechanism.

Reduced neutrophil apoptosis in diabetic mice during staphylococcal infection leads to prolonged Tnfα production and reduced neutrophil clearance.

A microfluidic platform for rapid, stress-induced antibiotic susceptibility testing of Staphylococcus aureus.

Staphylococcus aureus NorD, a putative efflux pump coregulated with the Opp1 oligopeptide permease, contributes selectively to fitness in vivo.

Opsonic and protective properties of antibodies raised to conjugate vaccines targeting six Staphylococcus aureus antigens.

Production of capsular polysaccharide does not influence Staphylococcus aureus vancomycin susceptibility.

Protein Antigens Increase the Protective Efficacy of a Capsule-Based Vaccine against Staphylococcus aureus in a Rat Model of Osteomyelitis.

Extended Staphylococcus aureus persistence in cystic fibrosis is associated with bacterial adaptation.

Acapsular clinical Staphylococcus aureus isolates lack agr function.

Prevention of Staphylococcus aureus Infections by Glycoprotein Vaccines Synthesized in Escherichia coli.