Consiglio Nazionale delle Ricerche
2 ARTICLES PUBLISHED IN JoVE
Neuroscience
Flash Photolysis of Caged Compounds in the Cilia of Olfactory Sensory Neurons
Anna Boccaccio 1,2, Claudia Sagheddu 1, Anna Menini 1,3
1SISSA, International School for Advanced Studies, 2Istituto di Biofisica, Consiglio Nazionale delle Ricerche, 3SISSA Unit, Italian Institute of Technology
Photolysis of caged compounds allows the production of rapid and localized increases in the concentration of various physiologically active compounds. Here, we show how to obtain patch-clamp recordings combined with photolysis of caged cAMP or caged Ca for the study of olfactory transduction in dissociated mouse olfactory sensory neurons.
Education
Free Radicals in Chemical Biology: from Chemical Behavior to Biomarker Development
Chryssostomos Chatgilialoglu 1, Carla Ferreri 1, Annalisa Masi 1, Michele Melchiorre 1, Anna Sansone 1, Michael A. Terzidis 1, Armida Torreggiani 1
1ISOF - Bio Free Radicals, Consiglio Nazionale delle Ricerche
Radical-based biomimetic chemistry has been applied to building-up libraries necessary for biomarker development.
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