Accedi

Jiangsu university

2 ARTICLES PUBLISHED IN JoVE

Bioengineering

Bioinspired Soft Robot with Incorporated Microelectrodes

Ting Wang^1,2, Bianca Migliori^1,3, Beatrice Miccoli^1,4, Su Ryon Shin¹

¹Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, ²School of Medicine, Jiangsu University, ³Tech4Health and Neuroscience Institutes, NYU Langone Health, ⁴Department of Electronics and Telecommunication, Politecnico di Torino

A bioinspired scaffold is fabricated by a soft photolithography technique using mechanically robust and electrically conductive hydrogels. The micropatterned hydrogels provide directional cardiomyocyte cell alignment, resulting in a tailored direction of actuation. Flexible microelectrodes are also integrated into the scaffold to bring electrical controllability for a self-actuating cardiac tissue.

JoVE Core

Direct Reprogramming of Mouse Fibroblasts into Melanocytes

Yi-Xuan Zhang^1,2, Li-Ping Liu^1,2, Ming Jin^1,2, Hui Sun^1,2, Han-Lin Zhang^1,2, Yu-Mei Li^1,2

¹Institute for Regenerative Medicine, Jiangsu University, ²Department of Dermatology, Affiliated Hospital of Jiangsu University

Here, we describe an optimized direct reprogramming system for melanocytes and a high-efficiency, concentrated virus packaging system that ensures smooth direct reprogramming.