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Mayo Clinic College of Medicine and Science

1 ARTICLES PUBLISHED IN JoVE

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Cancer Research

Using CRISPR/Cas9 to Knock Out GM-CSF in CAR-T Cells
Rosalie M. Sterner 1,2, Michelle J. Cox 3, Reona Sakemura 3, Saad S. Kenderian 2,3
1Mayo Clinic Medical Scientist Training Program, Mayo Clinic College of Medicine and Science, 2Department of Immunology, Mayo Clinic, 3Division of Hematology, Mayo Clinic

Here, we present a protocol to genetically edit CAR-T cells via a CRISPR/Cas9 system.

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