Automated Counterflow Centrifugal System for Small-Scale Cell ProcessingAnqi Li 1,2, Stephen Wilson 3, Ian Fitzpatrick 3, Mehri Barabadi 1,2, Siow Teng Chan 1, Mirja Krause 1,2, Gina Diamanta Kusuma 1,2, David James 3, Rebecca Lim 1,2,4
1The Ritchie Centre, Hudson Institute of Medical Research, 2Department of Obstetrics and Gynaecology, Monash University, 3Scinogy, 4Australian Regenerative Medicine Institute, Monash University
Automation is key to upscaling and cost management in cell manufacturing. This manuscript describes the use of a counterflow centrifugal cell processing device for automating the buffer exchange and cell concentration steps for small-scale bioprocessing.
