JoVE Logo

Accedi

Tekirdag Namik Kemal University School of Medicine

1 ARTICLES PUBLISHED IN JoVE

image

Developmental Biology

Transuterine Fetal Tracheal Occlusion Model in Mice
Emrah Aydın 1,2, Rashika Joshi 3, Marc Oria 1, Foong-Yen Lim 1, Brian Michael Varisco 3, Jose Luis Peiro 1
1The Center for Fetal, Cellular & Molecular Therapy, Cincinnati Fetal Center, Division of Pediatric General and Thoracic Surgery, Cincinnati Children’s Hospital Medical Center, 2Department of Pediatric Surgery, Tekirdag Namik Kemal University School of Medicine, 3The Division of Critical Care Medicine, Department of Pediatrics, Cincinnati Children’s Hospital Medical Center

Various animal models of congenital diaphragmatic hernia and fetal tracheal occlusion present advantages and disadvantages regarding ethical issues, cost, surgical difficulty, size, survival rates, and availability of genetic tools. This model provides a new tool to study the impact of both tracheal occlusion and increased luminal pressure on lung development.

JoVE Logo

Riservatezza

Condizioni di utilizzo

Politiche

Ricerca

Didattica

CHI SIAMO

Copyright © 2024 MyJoVE Corporation. Tutti i diritti riservati