Dorsal Root Ganglion Injection and Dorsal Root Crush Injury as a Model for Sensory Axon RegenerationMenghon Cheah 1, James W. Fawcett 1, Melissa R. Andrews 2,3
1John van Geest Center for Brain Repair, University of Cambridge, 2School of Medicine, University of St. Andrews, 3Department of Biological Sciences, University of Southampton
This protocol presents the use of a dorsal root ganglion (DRG) injection with a viral vector and a concurrent dorsal root crush injury in an adult rat as a model to study sensory axon regeneration. This model is suitable for investigating the use of gene therapy to promote sensory axon regeneration.
