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Capitolo 11

Ulteriori Ruoli del DNA

Attenuazione della trascrizione nei procarioti
Attenuazione della trascrizione nei procarioti
Transcriptional attenuation occurs when RNA transcription is prematurely terminated due to the formation of a terminator mRNA hairpin ...
Riboswitches (interruttori genici a RNA)
Riboswitches (interruttori genici a RNA)
Riboswitches are non-coding mRNA domains that regulate the transcription and translation of downstream genes without the help of proteins. Riboswitches ...
Modificazione dell'RNA
Modificazione dell'RNA
RNA editing is a post-transcriptional modification where a precursor mRNA (pre-mRNA) nucleotide sequence is changed by base insertion, deletion, or ...
Trasporto regolato dell'mRNA
Trasporto regolato dell'mRNA
In eukaryotes, transcription and translation are compartmentalized; an mRNA is first synthesized in the nucleus and then selectively transported to the ...
Leaky Scanning
Leaky Scanning
During most eukaryotic translation processes, the small 40S ribosome subunit scans an mRNA from its 5' end until it encounters the first start AUG ...
Stabilità dell'mRNA ed espressione genica
Stabilità dell'mRNA ed espressione genica
The structure and stability of mRNA molecules regulates gene expression, as mRNAs are a key step in the pathway from gene to protein. In eukaryotes, the ...
RNA Interference
RNA Interference
RNA interference (RNAi) is a process in which a small non-coding RNA molecule blocks the post-transcriptional expression of a gene by binding to its ...
MicroRNA
MicroRNA
MicroRNA (miRNA) are short, regulatory RNA transcribed from introns—non-coding regions of a gene—or intergenic regions—stretches of DNA ...
siRNA - Small Interfering RNAs
siRNA - Small Interfering RNAs
Small interfering RNAs, or siRNAs, are short regulatory RNA molecules that can silence genes post-transcriptionally, as well as the transcriptional ...
piRNA - Piwi-interacting RNAs
piRNA - Piwi-interacting RNAs
PIWI-interacting RNAs, or piRNAs, are the most abundant short non-coding RNAs. More than 20,000 genes have been found in humans that code for piRNAs while ...
CRISPR e crRNAs
CRISPR e crRNAs
Bacteria and archaea are susceptible to viral infections just like eukaryotes; therefore, they have developed a unique adaptive immune system to protect ...
lncRNA - Long Non-coding RNAs
lncRNA - Long Non-coding RNAs
In humans, more than 80% of the genome gets transcribed. However, only around 2% of the genome codes for proteins. The remaining part produces non-coding ...
RIboenzimi
RIboenzimi
The term ribozyme is used for RNA that can act as an enzyme. Ribozymes are mainly found in selected viruses, bacteria, plant organelles, and lower ...
Le condizioni sulla terra primordiale
Le condizioni sulla terra primordiale
Around 4 billion years ago, oceans began to condense on earth while volcanic eruptions released nitrogen, carbon dioxide, methane, ammonia, and hydrogen ...
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