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In This Article

  • Summary
  • Abstract
  • Introduction
  • Protocol
  • Representative Results
  • Discussion
  • Acknowledgements
  • Materials
  • References
  • Reprints and Permissions

Summary

Here, we present a protocol to treat chronic orchialgia by microsurgical denervation of the spermatic cord. Combined with the use of a microvascular doppler, the procedures can be more easily implemented.

Abstract

Chronic orchialgia is a common disease in department of urology and andrology. The etiology is complex, and the treatment is difficult. In severe cases, orchiectomy is even necessary. In recent years, microsurgical denervation of the spermatic cord (MDSC) is a minimally invasive and effective surgical method for the treatment of chronic orchialgia. Its greatest advantage is to preserve the testis and epididymis, avoid the possible organ resection. The key of the operation is to dissect all the fibrous tissues in the spermatic cord, while protecting the arteries (especially the testicular arteries) and several lymphatic vessels. Combined with the use of microvascular doppler in the operation, when separating the structure of spermatic cord under the microscope, the testicular arteries can be objectively and accurately protected (pulse “whistle” sound can be heard when the microvascular doppler probes the arterial surface), while artery injury and venous missed ligation can be avoided. The postoperative blood supply of the testis is also maximumly safeguarded. At the same time, we can be more fearless to cut the cremaster muscle, fatty and connective tissues surrounding the spermatic cord blood vessels and vas deferens after the arteries and lymphatic vessels being accurately protected under the microscope, finally achieve the spermatic cord completely "skeletonized" (only the testicular arteries, lymphatic vessels and vas deferens remained after the surgery). Thus we can better ensure the clinical curative effect (denervation thoroughly), avoid serious complications (testicular atrophy), and achieve better surgical results.

Introduction

Chronic orchialgia is a common disease accounting for about 2.5%–4.8% of all urology clinic visits1, which has been defined as more than 3 months of unilateral or bilateral scrotal pain interfering with daily life that ultimately leads to the pursuit of treatment2,3. The etiology is complex, and up to 50% of patients have no obvious etiology4. The exact mechanism is still unclear. Wallerian degeneration in peripheral nerves has been shown to be a potential cause of chronic pain5,6.

Protocol

The protocol was conducted in accordance with the Declaration of Helsinki, and the protocol was approved by the ethics committee of the First Affiliated Hospital of Sun Yat-sen University. Chronic orchialgia patients who failed conservative treatment were admitted and signed informed consent.

1. Instruments for operation

  1. Ensure the availability of the surgical microscope and microvascular doppler.

2. Preparation

Representative Results

In total, 26 chronic orchialgia patients were admitted to the East Division of the First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China, between March 2011 and June 2021 (Table 1). The average age of the patients was 39.9 ± 13.4 years. Within this group, 23 men underwent unilateral MDSC, and three men underwent bilateral MDSC successively. Prior to MDSC, all patients underwent spermatic cord block and had a positive response. The mixture we utilized comprises 5 mL of 2% lidocaine and .......

Discussion

Microsurgical denervation of the spermatic cord (MDSC) is a minimally invasive surgical option for treating chronic orchialgia after the failure of conservative treatments7,8. Significant reduction or elimination of pain is reported in various studies; the pain relief rate is about 80%4,10,11. Prior to MDSC, it is recommended that the patient undergo a spermatic cord blo.......

Acknowledgements

This study was supported by the Clinical Research Training Program, the East Division of the First Affiliated Hospital of Sun Yat-sen University (No.2019002, No.2019008).

....

Materials

NameCompanyCatalog NumberComments
Surgical microscopeLeicaModel M520 MC-1Leica operating microscope
Micro needle forcepsCheng-He,NingBoHC-A006microsurgery instrument
Micro scissorsCheng-He,NingBoHC-A008microsurgery instrument
Microscopic tweezersCheng-He,NingBoHC-A002microsurgery instrument
Microvascular dopplerVTIVTI 20 MHzintra-operative vascular Doppler flow detector

References

  1. Sigalos, J. T., Pastuszak, A. W. Chronic orchialgia: epidemiology, diagnosis and evaluation. Translational Andrology and Urology. 6, 37-43 (2017).
  2. Davis, B. E., Noble, M. J., Weigel, J. W., Foret, J. D., Mebust, W. K. Analysis and management o....

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