Steven L. Carroll

Neuregulin-1 and erbB4 immunoreactivity is associated with neuritic plaques in Alzheimer disease brain and in a transgenic model of Alzheimer disease.

Neuregulin-1 enhances motility and migration of human astrocytic glioma cells.

Lysophosphatidic acid promotes the proliferation of adult Schwann cells isolated from axotomized sciatic nerve.

Constitutive activation of the neuregulin-1/ErbB receptor signaling pathway is essential for the proliferation of a neoplastic Schwann cell line.

Hypertrophic neuropathies and malignant peripheral nerve sheath tumors in transgenic mice overexpressing glial growth factor beta3 in myelinating Schwann cells.

Constitutive activation of the neuregulin-1/erbB signaling pathway promotes the proliferation of a human peripheral neuroepithelioma cell line.

ErbB transmembrane tyrosine kinase receptors are expressed by sensory and motor neurons projecting into sciatic nerve.

Neuregulin-1beta induces neurite extension and arborization in cultured hippocampal neurons.

Tumor suppressor mutations and growth factor signaling in the pathogenesis of NF1-associated peripheral nerve sheath tumors. I. The role of tumor suppressor mutations.

Ganglion-specific patterns of diabetes-modulated gene expression are established in prevertebral and paravertebral sympathetic ganglia prior to the development of neuroaxonal dystrophy.

Improved gene delivery into neuroglial cells using a fiber-modified adenovirus vector.

Tumor suppressor mutations and growth factor signaling in the pathogenesis of NF1-associated peripheral nerve sheath tumors: II. The role of dysregulated growth factor signaling.

Neuregulin-1 enhances survival of human astrocytic glioma cells.

Activation of the neuregulin-1/ErbB signaling pathway promotes the proliferation of neoplastic Schwann cells in human malignant peripheral nerve sheath tumors.

Neuregulin growth factors and their ErbB receptors form a potential signaling network for schwannoma tumorigenesis.

Interactions between beta-neuregulin and neurotrophins in motor neuron apoptosis.

BH3-only proapoptotic Bcl-2 family members Noxa and Puma mediate neural precursor cell death.

Differential activation of c-fos and caspase-3 in hippocampal neuron subpopulations following neonatal hypoxia-ischemia.

How does the Schwann cell lineage form tumors in NF1?

Neuregulin-1 beta and neuregulin-1 alpha differentially affect the migration and invasion of malignant peripheral nerve sheath tumor cells.

Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions.

Tamoxifen inhibits malignant peripheral nerve sheath tumor growth in an estrogen receptor-independent manner.

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.

Genetically engineered mouse models shed new light on the pathogenesis of neurofibromatosis type I-related neoplasms of the peripheral nervous system.

Molecular mechanisms promoting the pathogenesis of Schwann cell neoplasms.

The pan erbB inhibitor PD168393 enhances lysosomal dysfunction-induced apoptotic death in malignant peripheral nerve sheath tumor cells.

Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis.

Combinatorial therapy with tamoxifen and trifluoperazine effectively inhibits malignant peripheral nerve sheath tumor growth by targeting complementary signaling cascades.

Classic Ras Proteins Promote Proliferation and Survival via Distinct Phosphoproteome Alterations in Neurofibromin-Null Malignant Peripheral Nerve Sheath Tumor Cells.

The Challenge of Cancer Genomics in Rare Nervous System Neoplasms: Malignant Peripheral Nerve Sheath Tumors as a Paradigm for Cross-Species Comparative Oncogenomics.

STAT1 and NF-κB Inhibitors Diminish Basal Interferon-Stimulated Gene Expression and Improve the Productive Infection of Oncolytic HSV in MPNST Cells.

Current status and recommendations for biomarkers and biobanking in neurofibromatosis.

Neuronal exosomes reveal Alzheimer's disease biomarkers in Down syndrome.

The Molecular and Morphologic Structures That Make Saltatory Conduction Possible in Peripheral Nerve.

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease.

Recent Advances in the Diagnosis and Pathogenesis of Neurofibromatosis Type 1 (NF1)-associated Peripheral Nervous System Neoplasms.

Pathology of nNOS-Expressing GABAergic Neurons in Mouse Model of Alzheimer's Disease.

Oridonin inhibits aberrant AKT activation in breast cancer.

Cutaneous neurofibromas: Current clinical and pathologic issues.

Complex Patterns of GABAergic Neuronal Deficiency and Type 2 Potassium-Chloride Cotransporter Immaturity in Human Focal Cortical Dysplasia.

The evolution and multi-molecular properties of NF1 cutaneous neurofibromas originating from C-fiber sensory endings and terminal Schwann cells at normal sites of sensory terminations in the skin.

ErbB4 promotes malignant peripheral nerve sheath tumor pathogenesis via Ras-independent mechanisms.

Mechanisms of Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) Action in Human Neoplasia.

The Proteome of the Dentate Terminal Zone of the Perforant Path Indicates Presynaptic Impairment in Alzheimer Disease.

Salinomycin targets the genome of radioresistant cells in glioblastomas.

Serum pro-BDNF levels correlate with phospho-tau staining in Alzheimer's disease.

Assessing interobserver variability and accuracy in the histological diagnosis and classification of cutaneous neurofibromass.

Each patient is a research biorepository: informatics-enabled research on surplus clinical specimens via the living BioBank.

Chemoembolizing hepatocellular carcinoma with microsphere cored with arsenic trioxide microcrystal.

Establishment and genomic characterization of a sporadic malignant peripheral nerve sheath tumor cell line.

The Potential Role of Small-Molecule PERK Inhibitor LDN-0060609 in Primary Open-Angle Glaucoma Treatment.

The Role of R-Ras Proteins in Normal and Pathologic Migration and Morphologic Change.

BH3 mimetics suppress CXCL12 expression in human malignant peripheral nerve sheath tumor cells.

R-Ras subfamily proteins elicit distinct physiologic effects and phosphoproteome alterations in neurofibromin-null MPNST cells.

Suppression of Fli-1 protects against pericyte loss and cognitive deficits in Alzheimer's disease.

The RASopathies: Biology, genetics and therapeutic options.

Priorities in Biobanking Research: A Report on the 2021 ISBER Round Table.

Developmental, neurochemical, and behavioral analyses of ErbB4 Cyt-1 knockout mice.

LPAR1 and aberrantly expressed LPAR3 differentially promote the migration and proliferation of malignant peripheral nerve sheath tumor cells.

Inhibition of Erb-B2 Receptor Tyrosine Kinase 3 and Associated Regulatory Pathways Potently Impairs Malignant Peripheral Nerve Sheath Tumor Proliferation and Survival.

Down Syndrome Biobank Consortium: A perspective.