Department of Pathology,
Department of Cell Biology and Neurobiology
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Neuregulin-1 and erbB4 immunoreactivity is associated with neuritic plaques in Alzheimer disease brain and in a transgenic model of Alzheimer disease.
Journal of neuropathology and experimental neurology Jan, 2003 | Pubmed ID: 12528817
Neuregulin-1 enhances motility and migration of human astrocytic glioma cells.
The Journal of biological chemistry Jun, 2003 | Pubmed ID: 12600989
Lysophosphatidic acid promotes the proliferation of adult Schwann cells isolated from axotomized sciatic nerve.
Journal of neuropathology and experimental neurology May, 2003 | Pubmed ID: 12769191
Constitutive activation of the neuregulin-1/ErbB receptor signaling pathway is essential for the proliferation of a neoplastic Schwann cell line.
Glia Aug, 2003 | Pubmed ID: 12838503
Hypertrophic neuropathies and malignant peripheral nerve sheath tumors in transgenic mice overexpressing glial growth factor beta3 in myelinating Schwann cells.
The Journal of neuroscience : the official journal of the Society for Neuroscience Aug, 2003 | Pubmed ID: 12917360
Constitutive activation of the neuregulin-1/erbB signaling pathway promotes the proliferation of a human peripheral neuroepithelioma cell line.
Journal of neuro-oncology Feb, 2004 | Pubmed ID: 15015657
ErbB transmembrane tyrosine kinase receptors are expressed by sensory and motor neurons projecting into sciatic nerve.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society Oct, 2004 | Pubmed ID: 15385576
Neuregulin-1beta induces neurite extension and arborization in cultured hippocampal neurons.
Molecular and cellular neurosciences Dec, 2004 | Pubmed ID: 15555917
Tumor suppressor mutations and growth factor signaling in the pathogenesis of NF1-associated peripheral nerve sheath tumors. I. The role of tumor suppressor mutations.
Journal of neuropathology and experimental neurology Nov, 2004 | Pubmed ID: 15581179
Ganglion-specific patterns of diabetes-modulated gene expression are established in prevertebral and paravertebral sympathetic ganglia prior to the development of neuroaxonal dystrophy.
Journal of neuropathology and experimental neurology Nov, 2004 | Pubmed ID: 15581182
Improved gene delivery into neuroglial cells using a fiber-modified adenovirus vector.
Biochemical and biophysical research communications Mar, 2005 | Pubmed ID: 15708001
Tumor suppressor mutations and growth factor signaling in the pathogenesis of NF1-associated peripheral nerve sheath tumors: II. The role of dysregulated growth factor signaling.
Journal of neuropathology and experimental neurology Jan, 2005 | Pubmed ID: 15715079
Neuregulin-1 enhances survival of human astrocytic glioma cells.
Glia Aug, 2005 | Pubmed ID: 15812817
Activation of the neuregulin-1/ErbB signaling pathway promotes the proliferation of neoplastic Schwann cells in human malignant peripheral nerve sheath tumors.
Oncogene Aug, 2005 | Pubmed ID: 15897877
Neuregulin growth factors and their ErbB receptors form a potential signaling network for schwannoma tumorigenesis.
Journal of neuropathology and experimental neurology Feb, 2006 | Pubmed ID: 16462207
Interactions between beta-neuregulin and neurotrophins in motor neuron apoptosis.
Journal of neurochemistry Apr, 2006 | Pubmed ID: 16524373
BH3-only proapoptotic Bcl-2 family members Noxa and Puma mediate neural precursor cell death.
The Journal of neuroscience : the official journal of the Society for Neuroscience Jul, 2006 | Pubmed ID: 16822983
Differential activation of c-fos and caspase-3 in hippocampal neuron subpopulations following neonatal hypoxia-ischemia.
Journal of neuroscience research Apr, 2008 | Pubmed ID: 18030677
How does the Schwann cell lineage form tumors in NF1?
Glia Nov, 2008 | Pubmed ID: 18803326
Neuregulin-1 beta and neuregulin-1 alpha differentially affect the migration and invasion of malignant peripheral nerve sheath tumor cells.
Glia Nov, 2009 | Pubmed ID: 19306381
Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions.
Nature genetics Mar, 2010 | Pubmed ID: 20154673
Tamoxifen inhibits malignant peripheral nerve sheath tumor growth in an estrogen receptor-independent manner.
Neuro-oncology Jan, 2011 | Pubmed ID: 21075781
Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
Nature genetics May, 2011 | Pubmed ID: 21460841
Genetically engineered mouse models shed new light on the pathogenesis of neurofibromatosis type I-related neoplasms of the peripheral nervous system.
Brain research bulletin Aug, 2011 | Pubmed ID: 21855613
Molecular mechanisms promoting the pathogenesis of Schwann cell neoplasms.
Acta neuropathologica Dec, 2011 | Pubmed ID: 22160322
The pan erbB inhibitor PD168393 enhances lysosomal dysfunction-induced apoptotic death in malignant peripheral nerve sheath tumor cells.
Neuro-oncology Jan, 2012 | Pubmed ID: 22259051
Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis.
Nature genetics Nov, 2012 | Pubmed ID: 23143602
Combinatorial therapy with tamoxifen and trifluoperazine effectively inhibits malignant peripheral nerve sheath tumor growth by targeting complementary signaling cascades.
Journal of neuropathology and experimental neurology Nov, 2014 | Pubmed ID: 25289889
Classic Ras Proteins Promote Proliferation and Survival via Distinct Phosphoproteome Alterations in Neurofibromin-Null Malignant Peripheral Nerve Sheath Tumor Cells.
Journal of neuropathology and experimental neurology Jun, 2015 | Pubmed ID: 25946318
The Challenge of Cancer Genomics in Rare Nervous System Neoplasms: Malignant Peripheral Nerve Sheath Tumors as a Paradigm for Cross-Species Comparative Oncogenomics.
The American journal of pathology Mar, 2016 | Pubmed ID: 26740486
STAT1 and NF-κB Inhibitors Diminish Basal Interferon-Stimulated Gene Expression and Improve the Productive Infection of Oncolytic HSV in MPNST Cells.
Molecular cancer research : MCR 05, 2016 | Pubmed ID: 26883073
Current status and recommendations for biomarkers and biobanking in neurofibromatosis.
Neurology Aug, 2016 | Pubmed ID: 27527649
Neuronal exosomes reveal Alzheimer's disease biomarkers in Down syndrome.
Alzheimer's & dementia : the journal of the Alzheimer's Association May, 2017 | Pubmed ID: 27755974
The Molecular and Morphologic Structures That Make Saltatory Conduction Possible in Peripheral Nerve.
Journal of neuropathology and experimental neurology 04, 2017 | Pubmed ID: 28340093
Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease.
Nature genetics 09, 2017 | Pubmed ID: 28714976
Recent Advances in the Diagnosis and Pathogenesis of Neurofibromatosis Type 1 (NF1)-associated Peripheral Nervous System Neoplasms.
Advances in anatomic pathology Sep, 2018 | Pubmed ID: 29762158
Pathology of nNOS-Expressing GABAergic Neurons in Mouse Model of Alzheimer's Disease.
Neuroscience 08, 2018 | Pubmed ID: 29782905
Oridonin inhibits aberrant AKT activation in breast cancer.
Oncotarget May, 2018 | Pubmed ID: 29844859
Cutaneous neurofibromas: Current clinical and pathologic issues.
Neurology 07, 2018 | Pubmed ID: 29987130
Complex Patterns of GABAergic Neuronal Deficiency and Type 2 Potassium-Chloride Cotransporter Immaturity in Human Focal Cortical Dysplasia.
Journal of neuropathology and experimental neurology 04, 2019 | Pubmed ID: 30856249
The evolution and multi-molecular properties of NF1 cutaneous neurofibromas originating from C-fiber sensory endings and terminal Schwann cells at normal sites of sensory terminations in the skin.
PloS one , 2019 | Pubmed ID: 31107888
ErbB4 promotes malignant peripheral nerve sheath tumor pathogenesis via Ras-independent mechanisms.
Cell communication and signaling : CCS 07, 2019 | Pubmed ID: 31291965
Mechanisms of Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) Action in Human Neoplasia.
The American journal of pathology 10, 2019 | Pubmed ID: 31351986
The Proteome of the Dentate Terminal Zone of the Perforant Path Indicates Presynaptic Impairment in Alzheimer Disease.
Molecular & cellular proteomics : MCP 01, 2020 | Pubmed ID: 31699905
Salinomycin targets the genome of radioresistant cells in glioblastomas.
Neuro-oncology 02, 2020 | Pubmed ID: 31784742
Serum pro-BDNF levels correlate with phospho-tau staining in Alzheimer's disease.
Neurobiology of aging 03, 2020 | Pubmed ID: 31882186
Assessing interobserver variability and accuracy in the histological diagnosis and classification of cutaneous neurofibromass.
Neuro-oncology advances Jul, 2020 | Pubmed ID: 32642737
Each patient is a research biorepository: informatics-enabled research on surplus clinical specimens via the living BioBank.
Journal of the American Medical Informatics Association : JAMIA 01, 2021 | Pubmed ID: 33166379
Chemoembolizing hepatocellular carcinoma with microsphere cored with arsenic trioxide microcrystal.
Drug delivery Nov, 2020 | Pubmed ID: 33307843
Establishment and genomic characterization of a sporadic malignant peripheral nerve sheath tumor cell line.
Scientific reports Mar, 2021 | Pubmed ID: 33707600
The Potential Role of Small-Molecule PERK Inhibitor LDN-0060609 in Primary Open-Angle Glaucoma Treatment.
International journal of molecular sciences Apr, 2021 | Pubmed ID: 33925820
The Role of R-Ras Proteins in Normal and Pathologic Migration and Morphologic Change.
The American journal of pathology Sep, 2021 | Pubmed ID: 34111428
BH3 mimetics suppress CXCL12 expression in human malignant peripheral nerve sheath tumor cells.
Oncotarget Jan, 2017 | Pubmed ID: 28055968
R-Ras subfamily proteins elicit distinct physiologic effects and phosphoproteome alterations in neurofibromin-null MPNST cells.
Cell communication and signaling : CCS Sep, 2021 | Pubmed ID: 34530870
Suppression of Fli-1 protects against pericyte loss and cognitive deficits in Alzheimer's disease.
Molecular therapy : the journal of the American Society of Gene Therapy Apr, 2022 | Pubmed ID: 35038582
The RASopathies: Biology, genetics and therapeutic options.
Advances in cancer research , 2022 | Pubmed ID: 35101235
Priorities in Biobanking Research: A Report on the 2021 ISBER Round Table.
Biopreservation and biobanking Feb, 2023 | Pubmed ID: 35507966
Developmental, neurochemical, and behavioral analyses of ErbB4 Cyt-1 knockout mice.
Journal of neurochemistry Jun, 2022 | Pubmed ID: 35523590
LPAR1 and aberrantly expressed LPAR3 differentially promote the migration and proliferation of malignant peripheral nerve sheath tumor cells.
Glia Mar, 2023 | Pubmed ID: 36416236
Inhibition of Erb-B2 Receptor Tyrosine Kinase 3 and Associated Regulatory Pathways Potently Impairs Malignant Peripheral Nerve Sheath Tumor Proliferation and Survival.
The American journal of pathology Sep, 2023 | Pubmed ID: 37328102
Down Syndrome Biobank Consortium: A perspective.
Alzheimer's & dementia : the journal of the Alzheimer's Association Mar, 2024 | Pubmed ID: 38270275
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