Seth Blackshaw

Neuronal nitric oxide synthase alternatively spliced forms: prominent functional localizations in the brain.

The development of excitatory synapses in cultured spinal neurons.

Developmental expression pattern of phototransduction components in mammalian pineal implies a light-sensing function.

Parapinopsin, a novel catfish opsin localized to the parapineal organ, defines a new gene family.

The 13-kD FK506 binding protein, FKBP13, interacts with a novel homologue of the erythrocyte membrane cytoskeletal protein 4.1.

Poly(ADP-ribose) polymerase-deficient mice are protected from streptozotocin-induced diabetes.

A novel neuron-enriched homolog of the erythrocyte membrane cytoskeletal protein 4.1.

Poly(ADP-ribosyl)ation basally activated by DNA strand breaks reflects glutamate-nitric oxide neurotransmission.

Profile of the genes expressed in the human peripheral retina, macula, and retinal pigment epithelium determined through serial analysis of gene expression (SAGE).

Applying genomics technologies to neural development.

Mutations in the inosine monophosphate dehydrogenase 1 gene (IMPDH1) cause the RP10 form of autosomal dominant retinitis pigmentosa.

The inherited blindness associated protein AIPL1 interacts with the cell cycle regulator protein NUB1.

Stem cells that know their place.

MicroSAGE is highly representative and reproducible but reveals major differences in gene expression among samples obtained from similar tissues.

Genomic analysis of mouse retinal development.

Clustering analysis of SAGE data using a Poisson approach.

Methionine adenosyltransferase:adrenergic-cAMP mechanism regulates a daily rhythm in pineal expression.

D-aspartate regulates melanocortin formation and function: behavioral alterations in D-aspartate oxidase-deficient mice.

Behavioural alterations in male mice lacking the gene for D-aspartate oxidase.

Serial analysis of gene expression (SAGE): experimental method and data analysis.

D-Aspartate and D-aspartate oxidase show selective and developmentally dynamic localization in mouse retina.

Serial analysis of gene expression (SAGE): experimental method and data analysis.

Pias3-dependent SUMOylation directs rod photoreceptor development.

New meaning in the message: noncoding RNAs and their role in retinal development.

Muscleblind-like 2: circadian expression in the mammalian pineal gland is controlled by an adrenergic-cAMP mechanism.

Profiling the human protein-DNA interactome reveals ERK2 as a transcriptional repressor of interferon signaling.

hPDI: a database of experimental human protein-DNA interactions.

A genomic atlas of mouse hypothalamic development.

The long noncoding RNA RNCR2 directs mouse retinal cell specification.

The orphan nuclear hormone receptor ERRbeta controls rod photoreceptor survival.

Three-dimensional diffusion tensor microimaging for anatomical characterization of the mouse brain.

Pias3-dependent SUMOylation controls mammalian cone photoreceptor differentiation.

Vertebrate retina and hypothalamus development.

Functional protein microarray technology.

Molecular pathways controlling development of thalamus and hypothalamus: from neural specification to circuit formation.

Dynamic spatiotemporal gene expression in embryonic mouse thalamus.

Region-specific gene expression in early postnatal mouse thalamus.

Systematic characterization of protein-DNA interactions.

Characterization of protein-DNA interactions using protein microarrays.

The Spalt family transcription factor Sall3 regulates the development of cone photoreceptors and retinal horizontal interneurons.

We contain multitudes: the protean face of retinoblastoma.

The long noncoding RNA Six3OS acts in trans to regulate retinal development by modulating Six3 activity.

Yeast one-hybrid assays for gene-centered human gene regulatory network mapping.

Regulation of CK2 by phosphorylation and O-GlcNAcylation revealed by semisynthesis.

Rapid identification of monospecific monoclonal antibodies using a human proteome microarray.

Injury-independent induction of reactive gliosis in retina by loss of function of the LIM homeodomain transcription factor Lhx2.

Botch promotes neurogenesis by antagonizing Notch.

Tanycytes of the hypothalamic median eminence form a diet-responsive neurogenic niche.

Identification of new autoantigens for primary biliary cirrhosis using human proteome microarrays.

WITHDRAWN: Functional implications of hypothalamic neurogenesis in the adult mammalian brain.

Functional implications of hypothalamic neurogenesis in the adult mammalian brain.

High-throughput RNA in situ hybridization in mouse retina.

Estrogen-related receptor β deletion modulates whole-body energy balance via estrogen-related receptor γ and attenuates neuropeptide Y gene expression.

Construction of human activity-based phosphorylation networks.

Identification of hypothalamic neuron-derived neurotrophic factor as a novel factor modulating appetite.

LHX2 is necessary for the maintenance of optic identity and for the progression of optic morphogenesis.

Bcl2-associated athanogene 3 interactome analysis reveals a new role in modulating proteasome activity.

Rax regulates hypothalamic tanycyte differentiation and barrier function in mice.

Estrogen-related receptor beta deficiency alters body composition and response to restraint stress.

Protein microarray characterization of the S-nitrosoproteome.

RNA Toxicity from the ALS/FTD C9ORF72 Expansion Is Mitigated by Antisense Intervention.

Feed your head: neurodevelopmental control of feeding and metabolism.

Stage-specific inhibition of TrkB activity leads to long-lasting and sexually dimorphic effects on body weight and hypothalamic gene expression.

Rax-CreERT2 knock-in mice: a tool for selective and conditional gene deletion in progenitor cells and radial glia of the retina and hypothalamus.

Lhx1 controls terminal differentiation and circadian function of the suprachiasmatic nucleus.

Long non-coding RNA-dependent transcriptional regulation in neuronal development and disease.

Dietary and sex-specific factors regulate hypothalamic neurogenesis in young adult mice.

Characterization of the SUMO-binding activity of the myeloproliferative and mental retardation (MYM)-type zinc fingers in ZNF261 and ZNF198.

Serine racemase regulated by binding to stargazin and PSD-95: potential N-methyl-D-aspartate-α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (NMDA-AMPA) glutamate neurotransmission cross-talk.

Notch3 interactome analysis identified WWP2 as a negative regulator of Notch3 signaling in ovarian cancer.

The LIM homeodomain factor Lhx2 is required for hypothalamic tanycyte specification and differentiation.

A conserved regulatory logic controls temporal identity in mouse neural progenitors.

Patterning, specification, and differentiation in the developing hypothalamus.

Identification of SUMO E3 ligase-specific substrates using the HuProt human proteome microarray.

Constructing the suprachiasmatic nucleus: a watchmaker's perspective on the central clockworks.

EphA4 is Involved in Sleep Regulation but Not in the Electrophysiological Response to Sleep Deprivation.

Lhx2 Is an Essential Factor for Retinal Gliogenesis and Notch Signaling.

The nutrient sensor OGT in PVN neurons regulates feeding.

Penetrance of Congenital Heart Disease in a Mouse Model of Down Syndrome Depends on a Trisomic Potentiator of a Disomic Modifier.

Multiple intrinsic factors act in concert with Lhx2 to direct retinal gliogenesis.

Control of lens development by Lhx2-regulated neuroretinal FGFs.

The NIH Protein Capture Reagents Program (PCRP): a standardized protein affinity reagent toolbox.

The stage-dependent roles of Ldb1 and functional redundancy with Ldb2 in mammalian retinogenesis.

A nuclease that mediates cell death induced by DNA damage and poly(ADP-ribose) polymerase-1.

An LHX1-Regulated Transcriptional Network Controls Sleep/Wake Coupling and Thermal Resistance of the Central Circadian Clockworks.

The long non-coding RNA NEAT1 is responsive to neuronal activity and is associated with hyperexcitability states.

Global Analysis of SUMO-Binding Proteins Identifies SUMOylation as a Key Regulator of the INO80 Chromatin Remodeling Complex.

Assessing the model transferability for prediction of transcription factor binding sites based on chromatin accessibility.

Understanding the Role of lncRNAs in Nervous System Development.

Lhx6-positive GABA-releasing neurons of the zona incerta promote sleep.

Pax6 is essential for the generation of late-born retinal neurons and for inhibition of photoreceptor-fate during late stages of retinogenesis.

In Vivo Electroporation of Developing Mouse Retina.

Global Identification of Small Ubiquitin-related Modifier (SUMO) Substrates Reveals Crosstalk between SUMOylation and Phosphorylation Promotes Cell Migration.

Regulation and function of neurogenesis in the adult mammalian hypothalamus.

ATAC-Seq analysis reveals a widespread decrease of chromatin accessibility in age-related macular degeneration.

A toolbox of immunoprecipitation-grade monoclonal antibodies to human transcription factors.

Ldb1- and Rnf12-dependent regulation of Lhx2 controls the relative balance between neurogenesis and gliogenesis in the retina.

Foxd1 is required for terminal differentiation of anterior hypothalamic neuronal subtypes.

Antibody Specificity Profiling Using Protein Microarrays.

Asymmetric vasopressin signaling spatially organizes the master circadian clock.

Canonical Wnt signaling regulates patterning, differentiation and nucleogenesis in mouse hypothalamus and prethalamus.

Disruption of stromal hedgehog signaling initiates RNF5-mediated proteasomal degradation of PTEN and accelerates pancreatic tumor growth.

Conditional deletion of Des1 in the mouse retina does not impair the visual cycle in cones.

Epigenomic profiling of retinal progenitors reveals LHX2 is required for developmental regulation of open chromatin.

The selective estrogen receptor modulator raloxifene mitigates the effect of all--retinal toxicity in photoreceptor degeneration.

Single-Cell RNA-Seq Analysis of Retinal Development Identifies NFI Factors as Regulating Mitotic Exit and Late-Born Cell Specification.

Reactive microglia and IL1β/IL-1R1-signaling mediate neuroprotection in excitotoxin-damaged mouse retina.

Matrix-metalloproteinase expression and gelatinase activity in the avian retina and their influence on Müller glia proliferation.

Global Analysis of Intercellular Homeodomain Protein Transfer.

PanoView: An iterative clustering method for single-cell RNA sequencing data.

Clarin-1 expression in adult mouse and human retina highlights a role of Müller glia in Usher syndrome.

Photic generation of 11--retinal in bovine retinal pigment epithelium.

ASCOT identifies key regulators of neuronal subtype-specific splicing.

Tanycyte ablation in the arcuate nucleus and median eminence increases obesity susceptibility by increasing body fat content in male mice.

NF-κB signaling regulates the formation of proliferating Müller glia-derived progenitor cells in the avian retina.

Single-Cell Analysis of Human Retina Identifies Evolutionarily Conserved and Species-Specific Mechanisms Controlling Development.

Epigenetic hallmarks of age-related macular degeneration are recapitulated in a photosensitive mouse model.

The cellular and molecular landscape of hypothalamic patterning and differentiation from embryonic to late postnatal development.

Zeb2 regulates the balance between retinal interneurons and Müller glia by inhibition of BMP-Smad signaling.

Gene regulatory networks controlling vertebrate retinal regeneration.

Gene regulatory networks controlling differentiation, survival, and diversification of hypothalamic Lhx6-expressing GABAergic neurons.

Turning lead into gold: reprogramming retinal cells to cure blindness.

Temperature and species-dependent regulation of browning in retrobulbar fat.

Midkine is neuroprotective and influences glial reactivity and the formation of Müller glia-derived progenitor cells in chick and mouse retinas.