Solomon H. Snyder Department of Neuroscience,
Department of Neurology,
Department of Ophthalmology,
Center for High-Throughput Biology,
Institute for Cell Engineering
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Neuronal nitric oxide synthase alternatively spliced forms: prominent functional localizations in the brain.
Proceedings of the National Academy of Sciences of the United States of America Apr, 1997 | Pubmed ID: 9096405
The development of excitatory synapses in cultured spinal neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience Oct, 1997 | Pubmed ID: 9295380
Developmental expression pattern of phototransduction components in mammalian pineal implies a light-sensing function.
The Journal of neuroscience : the official journal of the Society for Neuroscience Nov, 1997 | Pubmed ID: 9334383
Parapinopsin, a novel catfish opsin localized to the parapineal organ, defines a new gene family.
The Journal of neuroscience : the official journal of the Society for Neuroscience Nov, 1997 | Pubmed ID: 9334384
The 13-kD FK506 binding protein, FKBP13, interacts with a novel homologue of the erythrocyte membrane cytoskeletal protein 4.1.
The Journal of cell biology Apr, 1998 | Pubmed ID: 9531554
Poly(ADP-ribose) polymerase-deficient mice are protected from streptozotocin-induced diabetes.
Proceedings of the National Academy of Sciences of the United States of America Mar, 1999 | Pubmed ID: 10077636
A novel neuron-enriched homolog of the erythrocyte membrane cytoskeletal protein 4.1.
The Journal of neuroscience : the official journal of the Society for Neuroscience Aug, 1999 | Pubmed ID: 10414974
Poly(ADP-ribosyl)ation basally activated by DNA strand breaks reflects glutamate-nitric oxide neurotransmission.
Proceedings of the National Academy of Sciences of the United States of America Feb, 2000 | Pubmed ID: 10677544
Profile of the genes expressed in the human peripheral retina, macula, and retinal pigment epithelium determined through serial analysis of gene expression (SAGE).
Proceedings of the National Academy of Sciences of the United States of America Jan, 2002 | Pubmed ID: 11756676
Applying genomics technologies to neural development.
Current opinion in neurobiology Feb, 2002 | Pubmed ID: 11861173
Mutations in the inosine monophosphate dehydrogenase 1 gene (IMPDH1) cause the RP10 form of autosomal dominant retinitis pigmentosa.
Human molecular genetics Mar, 2002 | Pubmed ID: 11875050
The inherited blindness associated protein AIPL1 interacts with the cell cycle regulator protein NUB1.
Human molecular genetics Oct, 2002 | Pubmed ID: 12374762
Stem cells that know their place.
Nature neuroscience Dec, 2002 | Pubmed ID: 12447376
MicroSAGE is highly representative and reproducible but reveals major differences in gene expression among samples obtained from similar tissues.
Genome biology , 2003 | Pubmed ID: 12620102
Genomic analysis of mouse retinal development.
PLoS biology Sep, 2004 | Pubmed ID: 15226823
Clustering analysis of SAGE data using a Poisson approach.
Genome biology , 2004 | Pubmed ID: 15239836
Methionine adenosyltransferase:adrenergic-cAMP mechanism regulates a daily rhythm in pineal expression.
The Journal of biological chemistry Jan, 2005 | Pubmed ID: 15504733
D-aspartate regulates melanocortin formation and function: behavioral alterations in D-aspartate oxidase-deficient mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience Mar, 2006 | Pubmed ID: 16525061
Behavioural alterations in male mice lacking the gene for D-aspartate oxidase.
Behavioural brain research Aug, 2006 | Pubmed ID: 16725213
Serial analysis of gene expression (SAGE): experimental method and data analysis.
Current protocols in molecular biology / edited by Frederick M. Ausubel ... [et al.] Oct, 2007 | Pubmed ID: 18265400
D-Aspartate and D-aspartate oxidase show selective and developmentally dynamic localization in mouse retina.
Experimental eye research Apr, 2008 | Pubmed ID: 18314103
Serial analysis of gene expression (SAGE): experimental method and data analysis.
Current protocols in human genetics / editorial board, Jonathan L. Haines ... [et al.] Apr, 2007 | Pubmed ID: 18428405
Pias3-dependent SUMOylation directs rod photoreceptor development.
Neuron Jan, 2009 | Pubmed ID: 19186166
New meaning in the message: noncoding RNAs and their role in retinal development.
Developmental dynamics : an official publication of the American Association of Anatomists Sep, 2009 | Pubmed ID: 19191220
Muscleblind-like 2: circadian expression in the mammalian pineal gland is controlled by an adrenergic-cAMP mechanism.
Journal of neurochemistry Jul, 2009 | Pubmed ID: 19457059
Profiling the human protein-DNA interactome reveals ERK2 as a transcriptional repressor of interferon signaling.
Cell Oct, 2009 | Pubmed ID: 19879846
hPDI: a database of experimental human protein-DNA interactions.
Bioinformatics (Oxford, England) Jan, 2010 | Pubmed ID: 19900953
A genomic atlas of mouse hypothalamic development.
Nature neuroscience Jun, 2010 | Pubmed ID: 20436479
The long noncoding RNA RNCR2 directs mouse retinal cell specification.
BMC developmental biology , 2010 | Pubmed ID: 20459797
The orphan nuclear hormone receptor ERRbeta controls rod photoreceptor survival.
Proceedings of the National Academy of Sciences of the United States of America Jun, 2010 | Pubmed ID: 20534447
Three-dimensional diffusion tensor microimaging for anatomical characterization of the mouse brain.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine Jul, 2010 | Pubmed ID: 20577980
Pias3-dependent SUMOylation controls mammalian cone photoreceptor differentiation.
Nature neuroscience Sep, 2010 | Pubmed ID: 20729845
Vertebrate retina and hypothalamus development.
Wiley interdisciplinary reviews. Systems biology and medicine Nov-Dec, 2009 | Pubmed ID: 20836003
Functional protein microarray technology.
Wiley interdisciplinary reviews. Systems biology and medicine May-Jun, 2011 | Pubmed ID: 20872749
Molecular pathways controlling development of thalamus and hypothalamus: from neural specification to circuit formation.
The Journal of neuroscience : the official journal of the Society for Neuroscience Nov, 2010 | Pubmed ID: 21068293
Dynamic spatiotemporal gene expression in embryonic mouse thalamus.
The Journal of comparative neurology Feb, 2011 | Pubmed ID: 21192082
Region-specific gene expression in early postnatal mouse thalamus.
The Journal of comparative neurology Feb, 2011 | Pubmed ID: 21192083
Systematic characterization of protein-DNA interactions.
Cellular and molecular life sciences : CMLS May, 2011 | Pubmed ID: 21207099
Characterization of protein-DNA interactions using protein microarrays.
Cold Spring Harbor protocols May, 2011 | Pubmed ID: 21536762
The Spalt family transcription factor Sall3 regulates the development of cone photoreceptors and retinal horizontal interneurons.
Development (Cambridge, England) Jun, 2011 | Pubmed ID: 21558380
We contain multitudes: the protean face of retinoblastoma.
Cancer cell Aug, 2011 | Pubmed ID: 21840479
The long noncoding RNA Six3OS acts in trans to regulate retinal development by modulating Six3 activity.
Neural development , 2011 | Pubmed ID: 21936910
Yeast one-hybrid assays for gene-centered human gene regulatory network mapping.
Nature methods Dec, 2011 | Pubmed ID: 22037702
Regulation of CK2 by phosphorylation and O-GlcNAcylation revealed by semisynthesis.
Nature chemical biology , 2012 | Pubmed ID: 22267120
Rapid identification of monospecific monoclonal antibodies using a human proteome microarray.
Molecular & cellular proteomics : MCP Feb, 2012 | Pubmed ID: 22307071
Injury-independent induction of reactive gliosis in retina by loss of function of the LIM homeodomain transcription factor Lhx2.
Proceedings of the National Academy of Sciences of the United States of America Mar, 2012 | Pubmed ID: 22393024
Botch promotes neurogenesis by antagonizing Notch.
Developmental cell Apr, 2012 | Pubmed ID: 22445366
Tanycytes of the hypothalamic median eminence form a diet-responsive neurogenic niche.
Nature neuroscience May, 2012 | Pubmed ID: 22446882
Identification of new autoantigens for primary biliary cirrhosis using human proteome microarrays.
Molecular & cellular proteomics : MCP Sep, 2012 | Pubmed ID: 22647870
WITHDRAWN: Functional implications of hypothalamic neurogenesis in the adult mammalian brain.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience Jul, 2012 | Pubmed ID: 22814121
Functional implications of hypothalamic neurogenesis in the adult mammalian brain.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience Dec, 2012 | Pubmed ID: 22867732
High-throughput RNA in situ hybridization in mouse retina.
Methods in molecular biology (Clifton, N.J.) , 2013 | Pubmed ID: 23150371
Estrogen-related receptor β deletion modulates whole-body energy balance via estrogen-related receptor γ and attenuates neuropeptide Y gene expression.
The European journal of neuroscience Apr, 2013 | Pubmed ID: 23360481
Construction of human activity-based phosphorylation networks.
Molecular systems biology , 2013 | Pubmed ID: 23549483
Identification of hypothalamic neuron-derived neurotrophic factor as a novel factor modulating appetite.
American journal of physiology. Regulatory, integrative and comparative physiology Jun, 2013 | Pubmed ID: 23576617
LHX2 is necessary for the maintenance of optic identity and for the progression of optic morphogenesis.
The Journal of neuroscience : the official journal of the Society for Neuroscience Apr, 2013 | Pubmed ID: 23595746
Bcl2-associated athanogene 3 interactome analysis reveals a new role in modulating proteasome activity.
Molecular & cellular proteomics : MCP Oct, 2013 | Pubmed ID: 23824909
Rax regulates hypothalamic tanycyte differentiation and barrier function in mice.
The Journal of comparative neurology Aug, 2013 | Pubmed ID: 23939786
Estrogen-related receptor beta deficiency alters body composition and response to restraint stress.
BMC physiology Sep, 2013 | Pubmed ID: 24053666
Protein microarray characterization of the S-nitrosoproteome.
Molecular & cellular proteomics : MCP Oct, 2013 | Pubmed ID: 24105792
RNA Toxicity from the ALS/FTD C9ORF72 Expansion Is Mitigated by Antisense Intervention.
Neuron Oct, 2013 | Pubmed ID: 24139042
Feed your head: neurodevelopmental control of feeding and metabolism.
Annual review of physiology , 2014 | Pubmed ID: 24274739
Stage-specific inhibition of TrkB activity leads to long-lasting and sexually dimorphic effects on body weight and hypothalamic gene expression.
PloS one , 2013 | Pubmed ID: 24312242
Rax-CreERT2 knock-in mice: a tool for selective and conditional gene deletion in progenitor cells and radial glia of the retina and hypothalamus.
PloS one , 2014 | Pubmed ID: 24699247
Lhx1 controls terminal differentiation and circadian function of the suprachiasmatic nucleus.
Cell reports May, 2014 | Pubmed ID: 24767996
Long non-coding RNA-dependent transcriptional regulation in neuronal development and disease.
Frontiers in genetics , 2014 | Pubmed ID: 24936207
Dietary and sex-specific factors regulate hypothalamic neurogenesis in young adult mice.
Frontiers in neuroscience , 2014 | Pubmed ID: 24982613
Characterization of the SUMO-binding activity of the myeloproliferative and mental retardation (MYM)-type zinc fingers in ZNF261 and ZNF198.
PloS one , 2014 | Pubmed ID: 25133527
Serine racemase regulated by binding to stargazin and PSD-95: potential N-methyl-D-aspartate-α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (NMDA-AMPA) glutamate neurotransmission cross-talk.
The Journal of biological chemistry Oct, 2014 | Pubmed ID: 25164819
Notch3 interactome analysis identified WWP2 as a negative regulator of Notch3 signaling in ovarian cancer.
PLoS genetics Oct, 2014 | Pubmed ID: 25356737
The LIM homeodomain factor Lhx2 is required for hypothalamic tanycyte specification and differentiation.
The Journal of neuroscience : the official journal of the Society for Neuroscience Dec, 2014 | Pubmed ID: 25505333
A conserved regulatory logic controls temporal identity in mouse neural progenitors.
Neuron Feb, 2015 | Pubmed ID: 25654255
Patterning, specification, and differentiation in the developing hypothalamus.
Wiley interdisciplinary reviews. Developmental biology Sep-Oct, 2015 | Pubmed ID: 25820448
Identification of SUMO E3 ligase-specific substrates using the HuProt human proteome microarray.
Methods in molecular biology (Clifton, N.J.) , 2015 | Pubmed ID: 25820740
Constructing the suprachiasmatic nucleus: a watchmaker's perspective on the central clockworks.
Frontiers in systems neuroscience , 2015 | Pubmed ID: 26005407
EphA4 is Involved in Sleep Regulation but Not in the Electrophysiological Response to Sleep Deprivation.
Sleep Mar, 2016 | Pubmed ID: 26612390
Lhx2 Is an Essential Factor for Retinal Gliogenesis and Notch Signaling.
The Journal of neuroscience : the official journal of the Society for Neuroscience Feb, 2016 | Pubmed ID: 26911688
The nutrient sensor OGT in PVN neurons regulates feeding.
Science (New York, N.Y.) Mar, 2016 | Pubmed ID: 26989246
Penetrance of Congenital Heart Disease in a Mouse Model of Down Syndrome Depends on a Trisomic Potentiator of a Disomic Modifier.
Genetics 06, 2016 | Pubmed ID: 27029737
Multiple intrinsic factors act in concert with Lhx2 to direct retinal gliogenesis.
Scientific reports 09, 2016 | Pubmed ID: 27605455
Control of lens development by Lhx2-regulated neuroretinal FGFs.
Development (Cambridge, England) 11, 2016 | Pubmed ID: 27633990
The NIH Protein Capture Reagents Program (PCRP): a standardized protein affinity reagent toolbox.
Nature methods 09, 2016 | Pubmed ID: 27684578
The stage-dependent roles of Ldb1 and functional redundancy with Ldb2 in mammalian retinogenesis.
Development (Cambridge, England) 11, 2016 | Pubmed ID: 27697904
A nuclease that mediates cell death induced by DNA damage and poly(ADP-ribose) polymerase-1.
Science (New York, N.Y.) 10, 2016 | Pubmed ID: 27846469
An LHX1-Regulated Transcriptional Network Controls Sleep/Wake Coupling and Thermal Resistance of the Central Circadian Clockworks.
Current biology : CB Jan, 2017 | Pubmed ID: 28017605
The long non-coding RNA NEAT1 is responsive to neuronal activity and is associated with hyperexcitability states.
Scientific reports 01, 2017 | Pubmed ID: 28054653
Global Analysis of SUMO-Binding Proteins Identifies SUMOylation as a Key Regulator of the INO80 Chromatin Remodeling Complex.
Molecular & cellular proteomics : MCP 05, 2017 | Pubmed ID: 28254775
Assessing the model transferability for prediction of transcription factor binding sites based on chromatin accessibility.
BMC bioinformatics Jul, 2017 | Pubmed ID: 28750606
Understanding the Role of lncRNAs in Nervous System Development.
Advances in experimental medicine and biology , 2017 | Pubmed ID: 28815543
Lhx6-positive GABA-releasing neurons of the zona incerta promote sleep.
Nature 08, 2017 | Pubmed ID: 28847002
Pax6 is essential for the generation of late-born retinal neurons and for inhibition of photoreceptor-fate during late stages of retinogenesis.
Developmental biology 12, 2017 | Pubmed ID: 28993200
In Vivo Electroporation of Developing Mouse Retina.
Methods in molecular biology (Clifton, N.J.) , 2018 | Pubmed ID: 29188509
Global Identification of Small Ubiquitin-related Modifier (SUMO) Substrates Reveals Crosstalk between SUMOylation and Phosphorylation Promotes Cell Migration.
Molecular & cellular proteomics : MCP 05, 2018 | Pubmed ID: 29438996
Regulation and function of neurogenesis in the adult mammalian hypothalamus.
Progress in neurobiology 11, 2018 | Pubmed ID: 29631023
ATAC-Seq analysis reveals a widespread decrease of chromatin accessibility in age-related macular degeneration.
Nature communications 04, 2018 | Pubmed ID: 29636475
A toolbox of immunoprecipitation-grade monoclonal antibodies to human transcription factors.
Nature methods 05, 2018 | Pubmed ID: 29638227
Ldb1- and Rnf12-dependent regulation of Lhx2 controls the relative balance between neurogenesis and gliogenesis in the retina.
Development (Cambridge, England) 04, 2018 | Pubmed ID: 29650591
Foxd1 is required for terminal differentiation of anterior hypothalamic neuronal subtypes.
Developmental biology 07, 2018 | Pubmed ID: 29679559
Antibody Specificity Profiling Using Protein Microarrays.
Methods in molecular biology (Clifton, N.J.) , 2018 | Pubmed ID: 29714021
Asymmetric vasopressin signaling spatially organizes the master circadian clock.
The Journal of comparative neurology 09, 2018 | Pubmed ID: 29931690
Canonical Wnt signaling regulates patterning, differentiation and nucleogenesis in mouse hypothalamus and prethalamus.
Developmental biology 10, 2018 | Pubmed ID: 30063881
Disruption of stromal hedgehog signaling initiates RNF5-mediated proteasomal degradation of PTEN and accelerates pancreatic tumor growth.
Life science alliance Oct, 2018 | Pubmed ID: 30456390
Conditional deletion of Des1 in the mouse retina does not impair the visual cycle in cones.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 04, 2019 | Pubmed ID: 30645148
Epigenomic profiling of retinal progenitors reveals LHX2 is required for developmental regulation of open chromatin.
Communications biology , 2019 | Pubmed ID: 31044167
The selective estrogen receptor modulator raloxifene mitigates the effect of all--retinal toxicity in photoreceptor degeneration.
The Journal of biological chemistry 06, 2019 | Pubmed ID: 31073029
Single-Cell RNA-Seq Analysis of Retinal Development Identifies NFI Factors as Regulating Mitotic Exit and Late-Born Cell Specification.
Neuron 06, 2019 | Pubmed ID: 31128945
Reactive microglia and IL1β/IL-1R1-signaling mediate neuroprotection in excitotoxin-damaged mouse retina.
Journal of neuroinflammation Jun, 2019 | Pubmed ID: 31170999
Matrix-metalloproteinase expression and gelatinase activity in the avian retina and their influence on Müller glia proliferation.
Experimental neurology 10, 2019 | Pubmed ID: 31251936
Global Analysis of Intercellular Homeodomain Protein Transfer.
Cell reports 07, 2019 | Pubmed ID: 31315049
PanoView: An iterative clustering method for single-cell RNA sequencing data.
PLoS computational biology 08, 2019 | Pubmed ID: 31469823
Clarin-1 expression in adult mouse and human retina highlights a role of Müller glia in Usher syndrome.
The Journal of pathology 02, 2020 | Pubmed ID: 31625146
Photic generation of 11--retinal in bovine retinal pigment epithelium.
The Journal of biological chemistry 12, 2019 | Pubmed ID: 31694912
ASCOT identifies key regulators of neuronal subtype-specific splicing.
Nature communications 01, 2020 | Pubmed ID: 31919425
Tanycyte ablation in the arcuate nucleus and median eminence increases obesity susceptibility by increasing body fat content in male mice.
Glia Oct, 2020 | Pubmed ID: 32173924
NF-κB signaling regulates the formation of proliferating Müller glia-derived progenitor cells in the avian retina.
Development (Cambridge, England) 05, 2020 | Pubmed ID: 32291273
Single-Cell Analysis of Human Retina Identifies Evolutionarily Conserved and Species-Specific Mechanisms Controlling Development.
Developmental cell 05, 2020 | Pubmed ID: 32386599
Epigenetic hallmarks of age-related macular degeneration are recapitulated in a photosensitive mouse model.
Human molecular genetics Aug, 2020 | Pubmed ID: 32691052
The cellular and molecular landscape of hypothalamic patterning and differentiation from embryonic to late postnatal development.
Nature communications 08, 2020 | Pubmed ID: 32868762
Zeb2 regulates the balance between retinal interneurons and Müller glia by inhibition of BMP-Smad signaling.
Developmental biology 12, 2020 | Pubmed ID: 32950463
Gene regulatory networks controlling vertebrate retinal regeneration.
Science (New York, N.Y.) 11, 2020 | Pubmed ID: 33004674
Gene regulatory networks controlling differentiation, survival, and diversification of hypothalamic Lhx6-expressing GABAergic neurons.
Communications biology Jan, 2021 | Pubmed ID: 33479483
Turning lead into gold: reprogramming retinal cells to cure blindness.
The Journal of clinical investigation Feb, 2021 | Pubmed ID: 33529169
Temperature and species-dependent regulation of browning in retrobulbar fat.
Scientific reports Feb, 2021 | Pubmed ID: 33542375
Midkine is neuroprotective and influences glial reactivity and the formation of Müller glia-derived progenitor cells in chick and mouse retinas.
Glia Feb, 2021 | Pubmed ID: 33569849
1Solomon H. Snyder Department of Neuroscience, Johns Hopkins School of Medicine,
2Department of Neurology, Johns Hopkins School of Medicine,
3Department of Ophthalmology, Johns Hopkins School of Medicine,
4Center for High-Throughput Biology, Johns Hopkins School of Medicine,
5Institute for Cell Engineering, Johns Hopkins School of Medicine
1Division of Biology, California Institute of Technology,
2Solomon H. Snyder Department of Neuroscience, Neurology, and Ophthalamology, Johns Hopkins University School of Medicine,
3Department of Radiation Oncology & Molecular Radiation Sciences, Johns Hopkins University School of Medicine,
4Department of Radiation Oncology, University Of Washington Medical Center,
5Institute for Cell Engineering and High-Throughput Biology Center, Johns Hopkins University School of Medicine
1Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine,
2Department of Psychiatry and Behavioral Science, The Johns Hopkins Hospital,
3Department of Ophthalmology, The Johns Hopkins Hospital,
4Department of Neurology, The Johns Hopkins Hospital,
5Institute for Cell Engineering, Johns Hopkins University School of Medicine,
6Kavli Neuroscience Discovery Institute, Johns Hopkins University School of Medicine