Daiqing Liao

Adenovirus E1B 55-kilodalton oncoprotein binds to Daxx and eliminates enhancement of p53-dependent transcription by Daxx.

PCAF is a coactivator for p73-mediated transactivation.

Sequestration of p53 in the cytoplasm by adenovirus type 12 E1B 55-kilodalton oncoprotein is required for inhibition of p53-mediated apoptosis.

Negative regulation of p53 functions by Daxx and the involvement of MDM2.

An EBF3-mediated transcriptional program that induces cell cycle arrest and apoptosis.

Repression of p53-mediated transcription by adenovirus E1B 55-kDa does not require corepressor mSin3A and histone deacetylases.

Identification of two independent SUMO-interacting motifs in Daxx: evolutionary conservation from Drosophila to humans and their biochemical functions.

Emerging roles of the EBF family of transcription factors in tumor suppression.

Inhibition of p53 by adenovirus type 12 E1B-55K deregulates cell cycle control and sensitizes tumor cells to genotoxic agents.

Downregulation of Mdm2 and Mdm4 enhances viral gene expression during adenovirus infection.

Small-molecule inhibitors of acetyltransferase p300 identified by high-throughput screening are potent anticancer agents.

p53 SUMOylation promotes its nuclear export by facilitating its release from the nuclear export receptor CRM1.

Identification and characterization of small-molecule inhibitors of lysine acetyltransferases.

Identification of histone deacetylase inhibitors with benzoylhydrazide scaffold that selectively inhibit class I histone deacetylases.

Microarray gene expression profiling reveals potential mechanisms of tumor suppression by the class I HDAC-selective benzoylhydrazide inhibitors.

Profiling technologies for the identification and characterization of small-molecule histone deacetylase inhibitors.

Intrinsic cellular signaling mechanisms determine the sensitivity of cancer cells to virus-induced apoptosis.

CBP/p300 Bromodomain Mediates Amyloid Formation.

βArrestin2 Mediates Renal Cell Carcinoma Tumor Growth.

Degradation of DAXX by adenovirus type 12 E1B-55K circumvents chemoresistance of ovarian cancer to cisplatin.

Inhibition of androgen receptor transactivation function by adenovirus type 12 E1A undermines prostate cancer cell survival.

DAXX in cancer: phenomena, processes, mechanisms and regulation.