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Hiroki Kobayashi

South Australian Health and Medical Research Institute (SAHMRI)

BIOGRAPHY

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PUBLICATIONS

Genetic editing of colonic organoids provides a molecularly distinct and orthotopic preclinical model of serrated carcinogenesis.

Gut 04, 2019 | Pubmed ID: 29666172

Cancer-associated fibroblasts in gastrointestinal cancer.

Nature reviews. Gastroenterology & hepatology 05, 2019 | Pubmed ID: 30778141

Roles of the Mesenchymal Stromal/Stem Cell Marker Meflin in Cardiac Tissue Repair and the Development of Diastolic Dysfunction.

Circulation research 08, 2019 | Pubmed ID: 31221024

Meflin-Positive Cancer-Associated Fibroblasts Inhibit Pancreatic Carcinogenesis.

Cancer research 10, 2019 | Pubmed ID: 31439548

Medium-throughput Drug Screening of Patient-derived Organoids from Colorectal Peritoneal Metastases to Direct Personalized Therapy.

Clinical cancer research : an official journal of the American Association for Cancer Research 07, 2020 | Pubmed ID: 32376656

The Balance of Stromal BMP Signaling Mediated by GREM1 and ISLR Drives Colorectal Carcinogenesis.

Gastroenterology 03, 2021 | Pubmed ID: 33197448

Stromal DLK1 promotes proliferation and inhibits differentiation of the intestinal epithelium during development.

American journal of physiology. Gastrointestinal and liver physiology 04, 2021 | Pubmed ID: 33470182

Delineating proinflammatory microenvironmental signals by ex vivo modeling of the immature intestinal stroma.

Scientific reports Mar, 2021 | Pubmed ID: 33785826

The BMP antagonist gremlin 1 contributes to the development of cortical excitatory neurons, motor balance and fear responses.

Development (Cambridge, England) 07, 2021 | Pubmed ID: 34184027

INSTITUTIONS

South Australian Health and Medical Research Institute (SAHMRI)

University of Adelaide

Nagoya University Graduate School of Medicine

JOVE ARTICLES

Portal Vein Injection of Colorectal Cancer Organoids to Study the Liver Metastasis Stroma

Hiroki Kobayashi^1,2,3,4,

Krystyna A. Gieniec^1,2,

Jia Q. Ng^1,2,

Jarrad Goyne^1,2,

Tamsin R. M. Lannagan^1,2,

Elaine M. Thomas^1,2,

Georgette Radford^1,2,

Tongtong Wang^1,2,

Nobumi Suzuki^1,2,5,

Mari Ichinose^1,2,

Josephine A. Wright²,

Laura Vrbanac^1,2,

Alastair D. Burt⁶,

Masahide Takahashi^3,4,7,

Atsushi Enomoto³,

Daniel L. Worthley²,

Susan L. Woods^1,2

¹Adelaide Medical School, University of Adelaide,

², South Australian Health and Medical Research Institute (SAHMRI),

³Department of Pathology, Nagoya University Graduate School of Medicine,

⁴Division of Molecular Pathology, Center for Neurological Disease and Cancer, Nagoya University Graduate School of Medicine,

⁵Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo,

⁶Translational and Clinical Research Institute, Newcastle University,

⁷International Center for Cell and Gene Therapy, Fujita Health University

Cancer Research

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