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Generation of Integration-free Induced Pluripotent Stem Cells from Human Peripheral Blood Mononuclear Cells Using Episomal Vectors

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09:45 min

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January 1st, 2017

DOI :

10.3791/55091-v

January 1st, 2017

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10,466 Views

Wei Wen¹, Jian-Ping Zhang¹, Wanqiu Chen², Cameron Arakaki², Xiaolan Li¹^,², David Baylink², Gary D. Botimer³, Jing Xu¹, Weiping Yuan¹, Tao Cheng¹^,⁴^,⁵^,⁶^,⁷, Xiao-Bing Zhang¹^,²

¹State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Disease Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, ²Division of Regenerative Medicine, Department of Medicine, Loma Linda University, ³Department of Orthopaedic Surgery, Loma Linda University, ⁴Center for Stem Cell Medicine, Chinese Academy of Medical Sciences, ⁵Department of Stem Cell & Regenerative Medicine, Peking Union Medical College, ⁶Collaborative Innovation Center for Cancer Medicine, ⁷Tianjin Key Laboratory of Blood Cell Therapy and Technology

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要約

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Induced Pluripotent Stem Cells

Peripheral Blood Mononuclear Cells

Episomal Vectors

Non integrating Reprogramming

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