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Generation of Human Neurons and Oligodendrocytes from Pluripotent Stem Cells for Modeling Neuron-Oligodendrocyte Interactions

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10:53 min

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November 9th, 2020

DOI :

10.3791/61778-v

November 9th, 2020

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4,394 Views

Benedetta Assetta*¹, Changyong Tang*¹^,², Jing Bian*³, Ryan O'Rourke¹, Kevin Connolly¹, Thomas Brickler³, Sundari Chetty³^,⁴, Yu-Wen Alvin Huang¹^,⁵^,⁶

¹Department of Molecular Biology, Cell Biology and Biochemistry, Brown University, ²Department of Neurology, The Third Affiliated Hospital of Sun Yat-Sen University, ³Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, ⁴Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, ⁵Department of Neurology, Warren Alpert Medical School of Brown University, ⁶Center for Translational Neuroscience, Robert J. and Nancy D. Carney Institute for Brain Science and Brown Institute for Translational Science, Brown University

章

文字起こし

要約

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Pluripotent Stem Cells

Neuron

Oligodendrocyte

Neurodegenerative Disease

Alzheimer s Disease

Neuron oligodendrocyte Interactions

HEK293T Cells

NGN2

Tetracycline Transactivator

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