David J. Sherratt

Asymmetric activation of Xer site-specific recombination by FtsK.

Osmoregulation of dimer resolution at the plasmid pJHCMW1 mwr locus by Escherichia coli XerCD recombination.

Interactions of protein complexes on supercoiled DNA: the mechanism of selective synapsis by Tn3 resolvase.

Accessory factors determine the order of strand exchange in Xer recombination at psi.

Complete nucleotide sequence of Klebsiella pneumoniae multiresistance plasmid pJHCMW1.

Functional analysis of the C-terminal domains of the site-specific recombinases XerC and XerD.

Species specificity in the activation of Xer recombination at dif by FtsK.

Spatial and temporal organization of replicating Escherichia coli chromosomes.

Bacterial chromosome dynamics.

The aminoglycoside 6'-N-acetyltransferase type Ib encoded by Tn1331 is evenly distributed within the cell's cytoplasm.

Decatenation of DNA circles by FtsK-dependent Xer site-specific recombination.

Recombination and chromosome segregation.

Engineering a 2D protein-DNA crystal.

Partition-associated incompatibility caused by random assortment of pure plasmid clusters.

Dancing around the divisome: asymmetric chromosome segregation in Escherichia coli.

Dissection of a functional interaction between the DNA translocase, FtsK, and the XerD recombinase.

Differences in resolution of mwr-containing plasmid dimers mediated by the Klebsiella pneumoniae and Escherichia coli XerC recombinases: potential implications in dissemination of antibiotic resistance genes.

Tracking of controlled Escherichia coli replication fork stalling and restart at repressor-bound DNA in vivo.

The two Escherichia coli chromosome arms locate to separate cell halves.

Regular cellular distribution of plasmids by oscillating and filament-forming ParA ATPase of plasmid pB171.

Double-stranded DNA translocation: structure and mechanism of hexameric FtsK.

Replication fork blockage by transcription factor-DNA complexes in Escherichia coli.

Sublethal concentrations of the aminoglycoside amikacin interfere with cell division without affecting chromosome dynamics.

The FtsK gamma domain directs oriented DNA translocation by interacting with KOPS.

Unlinking chromosome catenanes in vivo by site-specific recombination.

Independent positioning and action of Escherichia coli replisomes in live cells.

Visualizing genetic loci and molecular machines in living bacteria.

Molecular mechanism of sequence-directed DNA loading and translocation by FtsK.

Modulation of Escherichia coli sister chromosome cohesion by topoisomerase IV.

KOPS-guided DNA translocation by FtsK safeguards Escherichia coli chromosome segregation.

mwr Xer site-specific recombination is hypersensitive to DNA supercoiling.

FtsK translocation on DNA stops at XerCD-dif.

fpr, a deficient Xer recombination site from a Salmonella plasmid, fails to confer stability by dimer resolution: comparative studies with the pJHCMW1 mwr site.

The Escherichia coli DNA translocase FtsK.

Separating speed and ability to displace roadblocks during DNA translocation by FtsK.

A streptavidin variant with slower biotin dissociation and increased mechanostability.

Stoichiometry and architecture of active DNA replication machinery in Escherichia coli.

Independent segregation of the two arms of the Escherichia coli ori region requires neither RNA synthesis nor MreB dynamics.

Sequence-specific assembly of FtsK hexamers establishes directional translocation on DNA.

Activation of XerCD-dif recombination by the FtsK DNA translocase.

Replication and segregation of an Escherichia coli chromosome with two replication origins.

Small plasmids harboring qnrB19: a model for plasmid evolution mediated by site-specific recombination at oriT and Xer sites.

Single-molecule imaging of DNA curtains reveals mechanisms of KOPS sequence targeting by the DNA translocase FtsK.

Robustness and accuracy of cell division in Escherichia coli in diverse cell shapes.

Chromosome replication and segregation in bacteria.

In vivo architecture and action of bacterial structural maintenance of chromosome proteins.

Capturing reaction paths and intermediates in Cre-loxP recombination using single-molecule fluorescence.

Hydroxy-terminated conjugated polymer nanoparticles have near-unity bright fraction and reveal cholesterol-dependence of IGF1R nanodomains.

Breaking symmetry in SMCs.

Single-molecule DNA repair in live bacteria.

Replication-fork dynamics.

Conformational transitions during FtsK translocase activation of individual XerCD-dif recombination complexes.

High-copy bacterial plasmids diffuse in the nucleoid-free space, replicate stochastically and are randomly partitioned at cell division.

FtsK-dependent XerCD-dif recombination unlinks replication catenanes in a stepwise manner.

RecA bundles mediate homology pairing between distant sisters during DNA break repair.

Toxin Kid uncouples DNA replication and cell division to enforce retention of plasmid R1 in Escherichia coli cells.