Leda Raptis

The role of Hsp90N, a new member of the Hsp90 family, in signal transduction and neoplastic transformation.

Growth and isotopic labelling of adherent cells in small volumes of medium.

Gap junctional intercellular communication in cells isolated from urethane-induced tumors in A/J mice.

In situ electroporation of large numbers of cells using minimal volumes of material.

In situ electroporation of radioactive compounds into adherent cells.

Cell-to-cell adhesion modulates Stat3 activity in normal and breast carcinoma cells.

Adenovirus-5 E1A suppresses differentiation of 3T3 L1 preadipocytes at lower levels than required for induction of apoptosis.

Stat3 is required for full neoplastic transformation by the Simian Virus 40 large tumor antigen.

Differential effects of Stat3 inhibition in sparse vs confluent normal and breast cancer cells.

Differential effects of c-Ras upon transformation, adipocytic differentiation, and apoptosis mediated by the simian virus 40 large tumor antigen.

Synthesis, characterization and Stat3 inhibitory properties of the prototypical platinum(IV) anticancer drug, [PtCl3(NO2)(NH3)2] (CPA-7).

Electrode assemblies used for electroporation of cultured cells.

Electroporation of adherent cells in situ for the study of signal transduction and gap junctional communication.

Examination of gap junctional, intercellular communication by in situ electroporation on two co-planar indium-tin oxide electrodes.

Stat3 activity is required for gap junctional permeability in normal rat liver epithelial cells.

Cadherin-cadherin engagement promotes cell survival via Rac1/Cdc42 and signal transducer and activator of transcription-3.

Activated Rac1 requires gp130 for Stat3 activation, cell proliferation and migration.

Beyond structure, to survival: activation of Stat3 by cadherin engagement.

The simian virus 40 large tumor antigen activates cSrc and requires cSrc for full neoplastic transformation.

Housekeeping genes; expression levels may change with density of cultured cells.

Doubles game: Src-Stat3 versus p53-PTEN in cellular migration and invasion.

eIF2{alpha} Kinase PKR modulates the hypoxic response by Stat3-dependent transcriptional suppression of HIF-1{alpha}.

Characterization of the oncogenic activity of the novel TRIM59 gene in mouse cancer models.

The R(h)oads to Stat3: Stat3 activation by the Rho GTPases.

Mind the gap; regulation of gap junctional, intercellular communication by the SRC oncogene product and its effectors.

Stat3 is a positive regulator of gap junctional intercellular communication in cultured, human lung carcinoma cells.

Effects of SRC and STAT3 upon gap junctional, intercellular communication in lung cancer lines.

Automated Quantitative Analysis of p53, Cyclin D1, Ki67 and pERK Expression in Breast Carcinoma Does Not Differ from Expert Pathologist Scoring and Correlates with Clinico-Pathological Characteristics.

Engaged for survival: From cadherin ligation to STAT3 activation.

Stat3 and gap junctions in normal and lung cancer cells.

Preclinical characterization of signal transducer and activator of transcription 3 small molecule inhibitors for primary and metastatic brain cancer therapy.

Differential effects of polyoma virus middle tumor antigen mutants upon gap junctional, intercellular communication.

Regulation of HC11 mouse breast epithelial cell differentiation by the E-cadherin/Rac axis.