Department of Biology
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The ubiquitous chromatin protein DEK alters the structure of DNA by introducing positive supercoils.
The Journal of biological chemistry Jul, 2002 | Pubmed ID: 11997399
Structure-specific binding of the proto-oncogene protein DEK to DNA.
Nucleic acids research Dec, 2003 | Pubmed ID: 14627833
Functional domains of the ubiquitous chromatin protein DEK.
Molecular and cellular biology Jul, 2004 | Pubmed ID: 15199153
The DEK protein--an abundant and ubiquitous constituent of mammalian chromatin.
Gene Dec, 2004 | Pubmed ID: 15563827
The SAF-box domain of chromatin protein DEK.
Nucleic acids research , 2005 | Pubmed ID: 15722484
HP1 binds specifically to Lys26-methylated histone H1.4, whereas simultaneous Ser27 phosphorylation blocks HP1 binding.
The Journal of biological chemistry Nov, 2005 | Pubmed ID: 16127177
Chromatin dynamics during epigenetic reprogramming in the mouse germ line.
Nature Apr, 2008 | Pubmed ID: 18354397
Arginine methylation of the B cell antigen receptor promotes differentiation.
The Journal of experimental medicine Apr, 2010 | Pubmed ID: 20231378
Markers of murine embryonic and neural stem cells, neurons and astrocytes: reference points for developmental neurotoxicity testing.
ALTEX , 2010 | Pubmed ID: 20390237
Histone H2A C-terminus regulates chromatin dynamics, remodeling, and histone H1 binding.
PLoS genetics , 2010 | Pubmed ID: 21170357
Rapid, complete and large-scale generation of post-mitotic neurons from the human LUHMES cell line.
Journal of neurochemistry Dec, 2011 | Pubmed ID: 21434924
The DEK oncoprotein is a Su(var) that is essential to heterochromatin integrity.
Genes & development Apr, 2011 | Pubmed ID: 21460035
Methylation of H2AR29 is a novel repressive PRMT6 target.
Epigenetics & chromatin , 2011 | Pubmed ID: 21774791
Extensive transcriptional regulation of chromatin modifiers during human neurodevelopment.
PloS one , 2012 | Pubmed ID: 22590590
Epigenetic changes and disturbed neural development in a human embryonic stem cell-based model relating to the fetal valproate syndrome.
Human molecular genetics Sep, 2012 | Pubmed ID: 22723015
Human embryonic stem cell-derived test systems for developmental neurotoxicity: a transcriptomics approach.
Archives of toxicology Jan, 2013 | Pubmed ID: 23179753
Targeting histone modifications--epigenetics in cancer.
Current opinion in cell biology Apr, 2013 | Pubmed ID: 23347561
90K, an interferon-stimulated gene product, reduces the infectivity of HIV-1.
Retrovirology , 2013 | Pubmed ID: 24156545
Design principles of concentration-dependent transcriptome deviations in drug-exposed differentiating stem cells.
Chemical research in toxicology Mar, 2014 | Pubmed ID: 24383497
From transient transcriptome responses to disturbed neurodevelopment: role of histone acetylation and methylation as epigenetic switch between reversible and irreversible drug effects.
Archives of toxicology Jul, 2014 | Pubmed ID: 24935251
Lineage-specific regulation of epigenetic modifier genes in human liver and brain.
PloS one , 2014 | Pubmed ID: 25054330
Toxicogenomics directory of chemically exposed human hepatocytes.
Archives of toxicology Dec, 2014 | Pubmed ID: 25399406
Vaibhav Shinde*,1,
Stefanie Klima*,2,
Perumal Srinivasan Sureshkumar1,
Kesavan Meganathan1,
Smita Jagtap1,
Eugen Rempel3,
Jörg Rahnenführer3,
Jan Georg Hengstler4,
Tanja Waldmann2,
Jürgen Hescheler1,
Marcel Leist*,2,
Agapios Sachinidis*,1
1Center of Physiology and Pathophysiology, Institute of Neurophysiology, University of Cologne,
2Department of Biology, University of Konstanz,
3Department of Statistics, Technical University of Dortmund,
4Leibniz Research Centre for Working Environment and Human Factors, Technical University of Dortmund
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