Institute for Biomedical Engineering - Biointerface Laboratory,
Helmholtz Institute for Biomedical Engineering,
Biointerface Group,
Helmholtz Institute for Biomedical Engineering, Biointerface Group
Willi Jahnen-Dechent has not added Biography.
If you are Willi Jahnen-Dechent and would like to personalize this page please email our Author Liaison for assistance.
Erratum for Maler et al., "Key Role of the Scavenger Receptor MARCO in Mediating Adenovirus Infection and Subsequent Innate Responses of Macrophages".
mBio 09, 2017 | Pubmed ID: 28951479
Systemic inhibition of spontaneous calcification by the serum protein alpha 2-HS glycoprotein/fetuin.
Zeitschrift fur Kardiologie , 2001 | Pubmed ID: 11374033
alpha 2-HS glycoprotein/fetuin, a transforming growth factor-beta/bone morphogenetic protein antagonist, regulates postnatal bone growth and remodeling.
The Journal of biological chemistry May, 2002 | Pubmed ID: 11901155
Improved insulin sensitivity and resistance to weight gain in mice null for the Ahsg gene.
Diabetes Aug, 2002 | Pubmed ID: 12145157
Novel insights into uremic vascular calcification: role of matrix Gla protein and alpha-2-Heremans Schmid glycoprotein/fetuin.
Blood purification , 2002 | Pubmed ID: 12207096
Fine mapping of the H-kininogen binding site in plasma prekallikrein apple domain 2.
International immunopharmacology Dec, 2002 | Pubmed ID: 12489801
Structural basis of calcification inhibition by alpha 2-HS glycoprotein/fetuin-A. Formation of colloidal calciprotein particles.
The Journal of biological chemistry Apr, 2003 | Pubmed ID: 12556469
Association of low fetuin-A (AHSG) concentrations in serum with cardiovascular mortality in patients on dialysis: a cross-sectional study.
Lancet Mar, 2003 | Pubmed ID: 12642050
Deficiencies of calcium-regulatory proteins in dialysis patients: a novel concept of cardiovascular calcification in uremia.
Kidney international. Supplement May, 2003 | Pubmed ID: 12694317
Modulation of angiogenic functions in human macrophages by biomaterials.
Biomaterials Sep, 2003 | Pubmed ID: 12809767
The serum protein alpha 2-Heremans-Schmid glycoprotein/fetuin-A is a systemically acting inhibitor of ectopic calcification.
The Journal of clinical investigation Aug, 2003 | Pubmed ID: 12897203
Tissue distribution and activity testing suggest a similar but not identical function of fetuin-B and fetuin-A.
The Biochemical journal Nov, 2003 | Pubmed ID: 12943536
Functional expression of HGF and HGF receptor/c-met in adult human mesenchymal stem cells suggests a role in cell mobilization, tissue repair, and wound healing.
Stem cells (Dayton, Ohio) , 2004 | Pubmed ID: 15153617
Alpha 2-HS glycoprotein (fetuin-A) modulates murine skin tumorigenesis.
International journal of oncology Aug, 2004 | Pubmed ID: 15254728
alpha2HS-glycoprotein, an antagonist of transforming growth factor beta in vivo, inhibits intestinal tumor progression.
Cancer research Sep, 2004 | Pubmed ID: 15374947
Human vascular smooth muscle cells undergo vesicle-mediated calcification in response to changes in extracellular calcium and phosphate concentrations: a potential mechanism for accelerated vascular calcification in ESRD.
Journal of the American Society of Nephrology : JASN Nov, 2004 | Pubmed ID: 15504939
In vitro behavior of a porous TiO2/perlite composite and its surface modification with fibronectin.
Biomaterials Jun, 2005 | Pubmed ID: 15603777
The serum glycoprotein fetuin-A promotes Lewis lung carcinoma tumorigenesis via adhesive-dependent and adhesive-independent mechanisms.
Cancer research Jan, 2005 | Pubmed ID: 15695392
Do not be misguided by guidelines: the calcium x phosphate product can be a Trojan horse.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association Apr, 2005 | Pubmed ID: 15728269
Role of calcification inhibitors in the pathogenesis of vascular calcification in chronic kidney disease (CKD).
Kidney international Jun, 2005 | Pubmed ID: 15882271
Multifunctional roles for serum protein fetuin-a in inhibition of human vascular smooth muscle cell calcification.
Journal of the American Society of Nephrology : JASN Oct, 2005 | Pubmed ID: 16093453
Fetuin-A, a hepatocyte-specific protein that binds Plasmodium berghei thrombospondin-related adhesive protein: a potential role in infectivity.
Infection and immunity Sep, 2005 | Pubmed ID: 16113307
The effect of surface modification of a porous TiO2/perlite composite on the ingrowth of bone tissue in vivo.
Biomaterials Mar, 2006 | Pubmed ID: 16139880
Myocardial stiffness, cardiac remodeling, and diastolic dysfunction in calcification-prone fetuin-A-deficient mice.
Journal of the American Society of Nephrology : JASN Nov, 2005 | Pubmed ID: 16177000
CCAAT enhancer binding protein beta and hepatocyte nuclear factor 3beta are necessary and sufficient to mediate dexamethasone-induced up-regulation of alpha2HS-glycoprotein/fetuin-A gene expression.
Journal of molecular endocrinology Apr, 2006 | Pubmed ID: 16595698
Proteolytic processing by matrix metalloproteinases and phosphorylation by protein kinase CK2 of fetuin-A, the major globulin of fetal calf serum.
Biochimie Mar, 2007 | Pubmed ID: 17110014
Fetuin-A (AHSG) prevents extraosseous calcification induced by uraemia and phosphate challenge in mice.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association Jun, 2007 | Pubmed ID: 17389622
Vascular calcification and fetuin-A deficiency in chronic kidney disease.
Trends in cardiovascular medicine May, 2007 | Pubmed ID: 17482094
Assessment of stem cell/biomaterial combinations for stem cell-based tissue engineering.
Biomaterials Jan, 2008 | Pubmed ID: 17935776
Size-dependent cytotoxicity of gold nanoparticles.
Small (Weinheim an der Bergstrasse, Germany) Nov, 2007 | Pubmed ID: 17963284
Mineral chaperones: a role for fetuin-A and osteopontin in the inhibition and regression of pathologic calcification.
Journal of molecular medicine (Berlin, Germany) Apr, 2008 | Pubmed ID: 18080808
Hierarchical role of fetuin-A and acidic serum proteins in the formation and stabilization of calcium phosphate particles.
The Journal of biological chemistry May, 2008 | Pubmed ID: 18364352
Histidine-rich glycoprotein protects from systemic Candida infection.
PLoS pathogens Aug, 2008 | Pubmed ID: 18797515
Function follows form: shape complementarity and nanoparticle toxicity.
Nanomedicine (London, England) Oct, 2008 | Pubmed ID: 18817462
A shielding topology stabilizes the early stage protein-mineral complexes of fetuin-A and calcium phosphate: a time-resolved small-angle X-ray study.
Chembiochem : a European journal of chemical biology Mar, 2009 | Pubmed ID: 19222044
Type 3 cystatins; fetuins, kininogen and histidine-rich glycoprotein.
Frontiers in bioscience : a journal and virtual library , 2009 | Pubmed ID: 19273244
Fetuin-A protects against atherosclerotic calcification in CKD.
Journal of the American Society of Nephrology : JASN Jun, 2009 | Pubmed ID: 19389852
Secretion of fibrinolytic enzymes facilitates human mesenchymal stem cell invasion into fibrin clots.
Cells, tissues, organs , 2010 | Pubmed ID: 19390164
Gold nanoparticles of diameter 1.4 nm trigger necrosis by oxidative stress and mitochondrial damage.
Small (Weinheim an der Bergstrasse, Germany) Sep, 2009 | Pubmed ID: 19642089
The physiologic development of fetuin-a serum concentrations in children.
Pediatric research Dec, 2009 | Pubmed ID: 19690510
Sevelamer and the bone-vascular axis in chronic kidney disease: bone turnover, inflammation, and calcification regulation.
Kidney international. Supplement Dec, 2009 | Pubmed ID: 19946324
Peripheral administration of fetuin-A attenuates early cerebral ischemic injury in rats.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism Mar, 2010 | Pubmed ID: 19953099
Serological cardiovascular and mortality risk predictors in dialysis patients receiving sevelamer: a prospective study.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association Aug, 2010 | Pubmed ID: 20172849
Fetuin-A and cystatin C are endogenous inhibitors of human meprin metalloproteases.
Biochemistry Oct, 2010 | Pubmed ID: 20806899
Fetuin-A is a mineral carrier protein: small angle neutron scattering provides new insight on Fetuin-A controlled calcification inhibition.
Biophysical journal Dec, 2010 | Pubmed ID: 21156141
Enhanced platelet activation mediates the accelerated angiogenic switch in mice lacking histidine-rich glycoprotein.
PloS one , 2011 | Pubmed ID: 21264222
A hepatic protein, fetuin-A, occupies a protective role in lethal systemic inflammation.
PloS one , 2011 | Pubmed ID: 21347455
Impact of sirolimus, tacrolimus and mycophenolate mofetil on osteoclastogenesis--implications for post-transplantation bone disease.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association Dec, 2011 | Pubmed ID: 21622987
Fetuin-A regulation of calcified matrix metabolism.
Circulation research Jun, 2011 | Pubmed ID: 21659653
Exposure to uremic serum induces a procalcific phenotype in human mesenchymal stem cells.
Arteriosclerosis, thrombosis, and vascular biology Sep, 2011 | Pubmed ID: 21680902
A red herring in vascular calcification: 'nanobacteria' are protein-mineral complexes involved in biomineralization.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association Nov, 2011 | Pubmed ID: 21965584
Compatibility of different polymers for cord blood-derived hematopoietic progenitor cells.
Journal of materials science. Materials in medicine Jan, 2012 | Pubmed ID: 22071984
Effect of vitamin K2 supplementation on functional vitamin K deficiency in hemodialysis patients: a randomized trial.
American journal of kidney diseases : the official journal of the National Kidney Foundation Feb, 2012 | Pubmed ID: 22169620
A fluorescent method to determine vitamin K-dependent gamma-glutamyl carboxylase activity.
Analytical biochemistry Feb, 2012 | Pubmed ID: 22210513
Cytotoxicity of gold nanoparticles.
Methods in enzymology , 2012 | Pubmed ID: 22568908
Ex vivo expansion of cord blood-CD34(+) cells using IGFBP2 and Angptl-5 impairs short-term lymphoid repopulation in vivo.
Journal of tissue engineering and regenerative medicine Dec, 2013 | Pubmed ID: 22653714
Two-dimensional polymer-based cultures expand cord blood-derived hematopoietic stem cells and support engraftment of NSG mice.
Tissue engineering. Part C, Methods Jan, 2013 | Pubmed ID: 22712684
Clearance of fetuin-A--containing calciprotein particles is mediated by scavenger receptor-A.
Circulation research Aug, 2012 | Pubmed ID: 22753077
Cord blood-hematopoietic stem cell expansion in 3D fibrin scaffolds with stromal support.
Biomaterials Oct, 2012 | Pubmed ID: 22800538
Context dependent role of the CD36--thrombospondin--histidine-rich glycoprotein axis in tumor angiogenesis and growth.
PloS one , 2012 | Pubmed ID: 22808089
Fetuin-A function in systemic mineral metabolism.
Trends in cardiovascular medicine Nov, 2012 | Pubmed ID: 22902178
Vitamin K-antagonists accelerate atherosclerotic calcification and induce a vulnerable plaque phenotype.
PloS one , 2012 | Pubmed ID: 22952653
Nanoparticle-based test measures overall propensity for calcification in serum.
Journal of the American Society of Nephrology : JASN Oct, 2012 | Pubmed ID: 22956818
Accelerated growth plate mineralization and foreshortened proximal limb bones in fetuin-A knockout mice.
PloS one , 2012 | Pubmed ID: 23091616
Fetuin-a in the developing brain.
Developmental neurobiology May, 2013 | Pubmed ID: 23109215
Embryonic stem cell-derived M2-like macrophages delay cutaneous wound healing.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society Jan-Feb, 2013 | Pubmed ID: 23126541
High-sensitivity real-time analysis of nanoparticle toxicity in green fluorescent protein-expressing zebrafish.
Small (Weinheim an der Bergstrasse, Germany) Mar, 2013 | Pubmed ID: 23143852
Novel insights into osteogenesis and matrix remodelling associated with calcific uraemic arteriolopathy.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association Apr, 2013 | Pubmed ID: 23223222
The role of fetuin-A in physiological and pathological mineralization.
Calcified tissue international Oct, 2013 | Pubmed ID: 23277412
Fluorescent SNAP-tag galectin fusion proteins as novel tools in glycobiology.
Current pharmaceutical design , 2013 | Pubmed ID: 23431989
Fetuin-B, a liver-derived plasma protein is essential for fertilization.
Developmental cell Apr, 2013 | Pubmed ID: 23562279
Differential hERG ion channel activity of ultrasmall gold nanoparticles.
Proceedings of the National Academy of Sciences of the United States of America May, 2013 | Pubmed ID: 23630249
Molecularly stabilised ultrasmall gold nanoparticles: synthesis, characterization and bioactivity.
Nanoscale Jul, 2013 | Pubmed ID: 23743952
HRG regulates tumor progression, epithelial to mesenchymal transition and metastasis via platelet-induced signaling in the pre-tumorigenic microenvironment.
Angiogenesis Oct, 2013 | Pubmed ID: 23793459
Hepatocyte growth factor-loaded biomaterials for mesenchymal stem cell recruitment.
Stem cells international , 2013 | Pubmed ID: 23861688
Warfarin induces cardiovascular damage in mice.
Arteriosclerosis, thrombosis, and vascular biology Nov, 2013 | Pubmed ID: 23990204
Biofabrication under fluorocarbon: a novel freeform fabrication technique to generate high aspect ratio tissue-engineered constructs.
BioResearch open access Oct, 2013 | Pubmed ID: 24083093
In Vivo Nanotoxicity Testing using the Zebrafish Embryo Assay.
Journal of materials chemistry. B, Materials for biology and medicine Jun, 2013 | Pubmed ID: 24179674
Cell surface serine protease matriptase-2 suppresses fetuin-A/AHSG-mediated induction of hepcidin.
Biological chemistry Jan, 2015 | Pubmed ID: 25205713
Mammalian gamete fusion depends on the inhibition of ovastacin by fetuin-B.
Biological chemistry Oct, 2014 | Pubmed ID: 25205729
Arterial thrombosis is accelerated in mice deficient in histidine-rich glycoprotein.
Blood Apr, 2015 | Pubmed ID: 25691157
Cytotoxicity of Ultrasmall Gold Nanoparticles on Planktonic and Biofilm Encapsulated Gram-Positive Staphylococci.
Small (Weinheim an der Bergstrasse, Germany) Feb, 2015 | Pubmed ID: 25712910
Analysis of Ebola Virus Entry Into Macrophages.
The Journal of infectious diseases Apr, 2015 | Pubmed ID: 25877552
Calcification Propensity and Survival among Renal Transplant Recipients.
Journal of the American Society of Nephrology : JASN Apr, 2015 | Pubmed ID: 25925688
Association of high fetuin-B concentrations in serum with fertilization rate in IVF: a cross-sectional pilot study.
Human reproduction (Oxford, England) Mar, 2016 | Pubmed ID: 26759143
Letter to the Editor, concerning: "FGF23-regulated production of fetuin-A (AHSG) in osteocytes".
Bone 12, 2016 | Pubmed ID: 27260648
Down-regulation of the liver-derived plasma protein fetuin-B mediates reversible female infertility.
Molecular human reproduction 01, 2017 | Pubmed ID: 27733488
Recombinant fetuin-B protein maintains high fertilization rate in cumulus cell-free mouse oocytes.
Molecular human reproduction 01, 2017 | Pubmed ID: 27733489
Latent TGF-β binding protein-1 deficiency decreases female fertility.
Biochemical and biophysical research communications Jan, 2017 | Pubmed ID: 27956181
Prothrombin Loading of Vascular Smooth Muscle Cell-Derived Exosomes Regulates Coagulation and Calcification.
Arteriosclerosis, thrombosis, and vascular biology Mar, 2017 | Pubmed ID: 28104608
Post-weaning epiphysiolysis causes distal femur dysplasia and foreshortened hindlimbs in fetuin-A-deficient mice.
PloS one , 2017 | Pubmed ID: 29088242
Histidine-rich glycoprotein-induced vascular normalization improves EPR-mediated drug targeting to and into tumors.
Journal of controlled release : official journal of the Controlled Release Society 07, 2018 | Pubmed ID: 29730154
Targeting and Modulation of Liver Myeloid Immune Cells by Hard-Shell Microbubbles.
Advanced biosystems May, 2018 | Pubmed ID: 29876517
Cellular Clearance and Biological Activity of Calciprotein Particles Depend on Their Maturation State and Crystallinity.
Frontiers in immunology , 2018 | Pubmed ID: 30233585
Phosphate, Calcification in Blood, and Mineral Stress: The Physiologic Blood Mineral Buffering System and Its Association with Cardiovascular Risk.
International journal of nephrology , 2018 | Pubmed ID: 30245880
Fetuin-A protein distribution in mature inflamed and ischemic brain tissue.
PloS one , 2018 | Pubmed ID: 30412582
Mammalian plasma fetuin-B is a selective inhibitor of ovastacin and meprin metalloproteinases.
Scientific reports 01, 2019 | Pubmed ID: 30679641
Structure of mammalian plasma fetuin-B and its mechanism of selective metallopeptidase inhibition.
IUCrJ Mar, 2019 | Pubmed ID: 30867929
The C-terminal region of human plasma fetuin-B is dispensable for the raised-elephant-trunk mechanism of inhibition of astacin metallopeptidases.
Scientific reports 10, 2019 | Pubmed ID: 31604990
Apolipoprotein C3 induces inflammation and organ damage by alternative inflammasome activation.
Nature immunology 01, 2020 | Pubmed ID: 31819254
Lumenal calcification and microvasculopathy in fetuin-A-deficient mice lead to multiple organ morbidity.
PloS one , 2020 | Pubmed ID: 32074120
Microvasculopathy and soft tissue calcification in mice are governed by fetuin-A, magnesium and pyrophosphate.
PloS one , 2020 | Pubmed ID: 32074140
Nature's remedy to phosphate woes: calciprotein particles regulate systemic mineral metabolism.
Kidney international 04, 2020 | Pubmed ID: 32200857
Rapid calcification propensity testing in blood using a temperature controlled microfluidic polymer chip.
PloS one , 2020 | Pubmed ID: 32255786
Calciprotein particles: mineral behaving badly?
Current opinion in nephrology and hypertension 07, 2020 | Pubmed ID: 32404635
Mud in the blood: the role of protein-mineral complexes and extracellular vesicles in biomineralisation and calcification.
Journal of structural biology 10, 2020 | Pubmed ID: 32711043
Fetuin-A is a HIF target that safeguards tissue integrity during hypoxic stress.
Nature communications 01, 2021 | Pubmed ID: 33483479
Limited proteolysis by acrosin affects sperm-binding and mechanical resilience of the mouse zona pellucida.
Molecular human reproduction 03, 2021 | Pubmed ID: 33779727
Live Imaging of Calciprotein Particle Clearance and Receptor Mediated Uptake: Role of Calciprotein Monomers.
Frontiers in cell and developmental biology , 2021 | Pubmed ID: 33996793
Interleukin-1α Is a Central Regulator of Leukocyte-Endothelial Adhesion in Myocardial Infarction and in Chronic Kidney Disease.
Circulation 09, 2021 | Pubmed ID: 34192892
The E-modulus of the oocyte is a non-destructive measure of zona pellucida hardening.
Reproduction (Cambridge, England) 09, 2021 | Pubmed ID: 34320465
Development of the BioHybrid Assay: Combining Primary Human Vascular Smooth Muscle Cells and Blood to Measure Vascular Calcification Propensity.
Cells 08, 2021 | Pubmed ID: 34440866
JoVE 소개
Copyright © 2024 MyJoVE Corporation. 판권 소유