Human Genetics and Cognitive Functions,
CNRS URA 2182 'Genes,
synapses and cognition',
CNRS URA 2182 'Genes, synapses and cognition'
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Genetic markers in psychiatric genetics.
Methods in molecular medicine , 2003 | Pubmed ID: 12298376
Mutations of the X-linked genes encoding neuroligins NLGN3 and NLGN4 are associated with autism.
Nature genetics May, 2003 | Pubmed ID: 12669065
[Genetics of autism: from genome scans to candidate genes].
Médecine sciences : M/S Nov, 2003 | Pubmed ID: 14648479
Frequency and transmission of glutamate receptors GRIK2 and GRIK3 polymorphisms in patients with obsessive compulsive disorder.
Neuroreport Mar, 2004 | Pubmed ID: 15094479
Expression and genetic variability of PCDH11Y, a gene specific to Homo sapiens and candidate for susceptibility to psychiatric disorders.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics Jan, 2006 | Pubmed ID: 16331680
No human tryptophan hydroxylase-2 gene R441H mutation in a large cohort of psychiatric patients and control subjects.
Biological psychiatry Jul, 2006 | Pubmed ID: 16581035
Searching for ways out of the autism maze: genetic, epigenetic and environmental clues.
Trends in neurosciences Jul, 2006 | Pubmed ID: 16808981
Fragile X syndrome and autism at the intersection of genetic and neural networks.
Nature neuroscience Oct, 2006 | Pubmed ID: 17001341
Mutations in the gene encoding the synaptic scaffolding protein SHANK3 are associated with autism spectrum disorders.
Nature genetics Jan, 2007 | Pubmed ID: 17173049
Mapping autism risk loci using genetic linkage and chromosomal rearrangements.
Nature genetics Mar, 2007 | Pubmed ID: 17322880
[Genetics and business: in defence of free speech!].
Médecine sciences : M/S May, 2007 | Pubmed ID: 17502073
[Alterations in synapsis formation and function in autism disorders].
Médecine sciences : M/S Jan, 2008 | Pubmed ID: 18198104
Reduced social interaction and ultrasonic communication in a mouse model of monogenic heritable autism.
Proceedings of the National Academy of Sciences of the United States of America Feb, 2008 | Pubmed ID: 18227507
Analysis of X chromosome inactivation in autism spectrum disorders.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics Sep, 2008 | Pubmed ID: 18361425
An investigation of ribosomal protein L10 gene in autism spectrum disorders.
BMC medical genetics , 2009 | Pubmed ID: 19166581
A synaptic trek to autism.
Current opinion in neurobiology Apr, 2009 | Pubmed ID: 19545994
Reduced 3-O-methyl-dopa levels in OCD patients and their unaffected parents is associated with the low activity M158 COMT allele.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics Mar, 2010 | Pubmed ID: 19676096
[Autism: more evidence of a genetic cause].
Bulletin de l'Académie nationale de médecine Feb, 2009 | Pubmed ID: 19718887
Functional impact of global rare copy number variation in autism spectrum disorders.
Nature Jul, 2010 | Pubmed ID: 20531469
Mutation screening of NOS1AP gene in a large sample of psychiatric patients and controls.
BMC medical genetics , 2010 | Pubmed ID: 20602773
Key role for gene dosage and synaptic homeostasis in autism spectrum disorders.
Trends in genetics : TIG Aug, 2010 | Pubmed ID: 20609491
Identification of pathway-biased and deleterious melatonin receptor mutants in autism spectrum disorders and in the general population.
PloS one , 2010 | Pubmed ID: 20657642
A genome-wide scan for common alleles affecting risk for autism.
Human molecular genetics Oct, 2010 | Pubmed ID: 20663923
Production of soluble, active acetyl serotonin methyl transferase in Leishmania tarentolae.
Protein expression and purification Jan, 2011 | Pubmed ID: 20688166
Against le packing: a consensus statement.
Journal of the American Academy of Child and Adolescent Psychiatry Feb, 2011 | Pubmed ID: 21241956
Mutation screening of ASMT, the last enzyme of the melatonin pathway, in a large sample of patients with intellectual disability.
BMC medical genetics , 2011 | Pubmed ID: 21251267
Behavioral profiles of mouse models for autism spectrum disorders.
Autism research : official journal of the International Society for Autism Research Feb, 2011 | Pubmed ID: 21328568
Variations of the candidate SEZ6L2 gene on Chromosome 16p11.2 in patients with autism spectrum disorders and in human populations.
PloS one , 2011 | Pubmed ID: 21394203
Dynamics in enzymatic protein complexes offer a novel principle for the regulation of melatonin synthesis in the human pineal gland.
Journal of pineal research Aug, 2011 | Pubmed ID: 21517958
Genetic variations of the melatonin pathway in patients with attention-deficit and hyperactivity disorders.
Journal of pineal research Nov, 2011 | Pubmed ID: 21615493
A novel approach of homozygous haplotype sharing identifies candidate genes in autism spectrum disorder.
Human genetics Oct, 2011 | Pubmed ID: 21996756
Adult male mice emit context-specific ultrasonic vocalizations that are modulated by prior isolation or group rearing environment.
PloS one , 2012 | Pubmed ID: 22238608
Genetic variants of FOXP2 and KIAA0319/TTRAP/THEM2 locus are associated with altered brain activation in distinct language-related regions.
The Journal of neuroscience : the official journal of the Society for Neuroscience Jan, 2012 | Pubmed ID: 22262880
Genetic and functional analyses of SHANK2 mutations suggest a multiple hit model of autism spectrum disorders.
PLoS genetics Feb, 2012 | Pubmed ID: 22346768
SHANK1 Deletions in Males with Autism Spectrum Disorder.
American journal of human genetics May, 2012 | Pubmed ID: 22503632
Genetic and functional abnormalities of the melatonin biosynthesis pathway in patients with bipolar disorder.
Human molecular genetics Sep, 2012 | Pubmed ID: 22694957
Autistic-like behaviours and hyperactivity in mice lacking ProSAP1/Shank2.
Nature Jun, 2012 | Pubmed ID: 22699619
High-functioning autism spectrum disorder and fragile X syndrome: report of two affected sisters.
Molecular autism , 2012 | Pubmed ID: 22738402
Crystal structure and functional mapping of human ASMT, the last enzyme of the melatonin synthesis pathway.
Journal of pineal research Jan, 2013 | Pubmed ID: 22775292
Significant correlation between a set of genetic polymorphisms and a functional brain network revealed by feature selection and sparse Partial Least Squares.
NeuroImage Oct, 2012 | Pubmed ID: 22781162
Individual common variants exert weak effects on the risk for autism spectrum disorderspi.
Human molecular genetics Jul, 2012 | Pubmed ID: 22843504
Development of an autism severity score for mice using Nlgn4 null mutants as a construct-valid model of heritable monogenic autism.
Behavioural brain research Aug, 2013 | Pubmed ID: 23183221
Sequencing ASMT identifies rare mutations in Chinese Han patients with autism.
PloS one , 2013 | Pubmed ID: 23349736
Contactin 4, -5 and -6 differentially regulate neuritogenesis while they display identical PTPRG binding sites.
Biology open Mar, 2013 | Pubmed ID: 23519440
Progress toward treatments for synaptic defects in autism.
Nature medicine Jun, 2013 | Pubmed ID: 23744158
The genetic landscapes of autism spectrum disorders.
Annual review of genomics and human genetics , 2013 | Pubmed ID: 23875794
The Autism ProSAP1/Shank2 mouse model displays quantitative and structural abnormalities in ultrasonic vocalisations.
Behavioural brain research Nov, 2013 | Pubmed ID: 23994547
The emerging role of SHANK genes in neuropsychiatric disorders.
Developmental neurobiology Feb, 2014 | Pubmed ID: 24124131
Heterozygous FA2H mutations in autism spectrum disorders.
BMC medical genetics , 2013 | Pubmed ID: 24299421
Neurobiology of autism gene products: towards pathogenesis and drug targets.
Psychopharmacology Mar, 2014 | Pubmed ID: 24419271
Common variants in genes of the postsynaptic FMRP signalling pathway are risk factors for autism spectrum disorders.
Human genetics Jun, 2014 | Pubmed ID: 24442360
Screening, intervention and outcome in autism and other developmental disorders: the role of randomized controlled trials.
Journal of autism and developmental disorders Aug, 2014 | Pubmed ID: 24554162
Heterogeneous pattern of selective pressure for PRRT2 in human populations, but no association with autism spectrum disorders.
PloS one , 2014 | Pubmed ID: 24594579
Convergence of genes and cellular pathways dysregulated in autism spectrum disorders.
American journal of human genetics May, 2014 | Pubmed ID: 24768552
Genetic and Environmental Influences on the Visual Word Form and Fusiform Face Areas.
Cerebral cortex (New York, N.Y. : 1991) Sep, 2015 | Pubmed ID: 24825786
Vitamin d in the general population of young adults with autism in the faroe islands.
Journal of autism and developmental disorders Dec, 2014 | Pubmed ID: 24927807
Meta-analysis of SHANK Mutations in Autism Spectrum Disorders: a gradient of severity in cognitive impairments.
PLoS genetics Sep, 2014 | Pubmed ID: 25188300
Social communication in mice--are there optimal cage conditions?
PloS one , 2015 | Pubmed ID: 25806942
Neuroanatomical Diversity of Corpus Callosum and Brain Volume in Autism: Meta-analysis, Analysis of the Autism Brain Imaging Data Exchange Project, and Simulation.
Biological psychiatry Jul, 2015 | Pubmed ID: 25850620
The genetics and neurobiology of ESSENCE: The third Birgit Olsson lecture.
Nordic journal of psychiatry May, 2015 | Pubmed ID: 25971862
From the genetic architecture to synaptic plasticity in autism spectrum disorder.
Nature reviews. Neuroscience Aug, 2015 | Pubmed ID: 26289574
11q24.2-25 micro-rearrangements in autism spectrum disorders: Relation to brain structures.
American journal of medical genetics. Part A Sep, 2015 | Pubmed ID: 26334118
A de novo microdeletion of SEMA5A in a boy with autism spectrum disorder and intellectual disability.
European journal of human genetics : EJHG Sep, 2015 | Pubmed ID: 26395558
Laura Gouder1,2,3,
Jean-Yves Tinevez4,
Hany Goubran-Botros1,2,3,
Alexandra Benchoua5,
Thomas Bourgeron1,2,3,
Isabelle Cloëz-Tayarani1,2,3
1Human Genetics and Cognitive Functions, Institut Pasteur,
2CNRS URA 2182 'Genes, synapses and cognition', Institut Pasteur,
3Human Genetics and Cognitive Functions, Université Paris Diderot, Sorbonne Paris Cité,
4Plateforme d' Imagerie Dynamique, Imagopole, CiTech, Institut Pasteur,
5Neuroplasticity and Therapeutics, CECS, I-STEM, AFM, Evry
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